-
Name
ENDOMORPHIN-1
- EINECS
- CAS No. 189388-22-5
- Article Data9
- CAS DataBase
- Density 1.343 g/cm3
- Solubility
- Melting Point 144-146℃
- Formula C34H38N6O5
- Boiling Point 1052.765 °C at 760 mmHg
- Molecular Weight 610.713
- Flash Point 590.491 °C
- Transport Information
- Appearance Solid. (Solid powder.)
- Safety
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms L-Tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide;
- PSA 183.64000
- LogP 3.79490
Endomorphin 1 Chemical Properties
Formula :C34H38N6O5
M.W. 610.7
Solubility:soluble in water.
Chemcial structure:
Endomorphin 1 Specification
Endomorphin-1 (EM-1) should be stored at -20°C. Keep container tightly closed.Endomorphin-1 (189388-22-5) is a recently isolated endogenous peptide having potent analgesic activity and high affinity and selectivity for the mu-opioid receptor. Endomorphin-1 (189388-22-5) activates G proteins and inhibits adenylyl cyclase activity in membrane preparations from cells stably expressing the mu opioid receptor, an effect reversed by the mu receptor antagonist CTAP (D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2) . However, Endomorphin-1 appears to have no influence on cells stably expressing the delta opioid receptor.
Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) and endomorphin-2 (Tyr-Pro-Phe-Phe-NH2) are tetrapeptides with the highest known affinity and specificity for the μ opioid receptor.Endomorphin-1 is located in the nucleus of the solitary tract, the periventricular hypothalamus, and the dorsomedial hypothalamus, where it is found within histaminergic neurons and may regulate sedative and arousal behaviors.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View