Product Name

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  • Name

    Ergonovine maleate

  • EINECS 204-953-5
  • CAS No. 129-51-1
  • Density 1.3g/cm3
  • Solubility Sparingly soluble in water and ethanol (~750 g/l) TS; practically insoluble in ether R
  • Melting Point ca. 200 C
  • Formula C19H23N3O2.C4H4O4
  • Boiling Point 635.2 ºCat 760 mmHg
  • Molecular Weight 441.484
  • Flash Point 337.9 ºC
  • Transport Information UN 1544 6
  • Appearance white or faintly yellow, crystalline powder; odourless.
  • Safety 36/37-45
  • Risk Codes 23/24/25
  • Molecular Structure Molecular Structure of 129-51-1 (Ergonovine maleate)
  • Hazard Symbols ToxicT
  • Synonyms Metriclavin;Ergonovine, maleate (1:1);Ergotrate Maleate;Ergomet;Cornocentin;Ergometrine maleate (JP14);Ergotrate;Ergometrine (TN);D-Ergonovine maleate;Ergonovine maleate (USP);Ermetrin;Ergonovine maleate (TN);Ergoline-8-.beta.-carboxamide, 9, 10-didehydro-N- ((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt);Ergometrine acid maleate;Ergotrate maleate (TN);Ergometrin maleate;Ergoline-8.beta.-carboxamide, 9,10-didehydro-N- ((S)-2-hydroxy-1-methylethyl)-6-methyl-, maleate (1:1) (salt);Ergoline-8-carboxamide, 9, 10-didehydro-N- (2-hydroxy-1-methylethyl)-6-methyl-, [8.beta.(S)]-, (Z)-2-butenedioate (1:1) (salt);Ergonovine, maleate (1:1) (salt);Ergoline-8-carboxamide,9,10-didehydro-N- [(1S)-2-hydroxy-1-methylethyl]-6-methyl-,(8a)-,(2Z)-2-butenedioate (1:1) (salt);Oxytocic;Ergometrine maleate (1:1);Ergot;Ergometrine;Ergometrine maleate;ERGOT;ERGONO-VINE, MALEATE (1:1) (SALT);CRUDE ERGOT;
  • PSA 142.96000
  • LogP 1.57520

Ergonovine maleate Specification

  Ergonovine maleate (CAS NO.129-51-1) is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
  A deadly human poison. Experimental poison by intravenous route. Experimental reproductive effects. Human systemic effects: hypermotility, diarrhea, cyanosis, thirst, tachycardia, confusion, coma, central nervous system symptoms, gangrene; circulatory changes can follow ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also individual components. Ergonovine maleate (CAS NO.129-51-1) is one kind of dangerous material, because it has toxic by inhalation, in contact with skin and if swallowed, In case of accident or if you feel unwell, seek medical advice immediately (show label where possible). And its toxicity is:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intravenous 80mg/kg (80mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 398, 1935.
infant TDLo intramuscular 40ug/kg (0.04mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
JAMA, Journal of the American Medical Association. Vol. 250, Pg. 729, 1983.
man LDLo unreported 15mg/kg (15mg/kg)   "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LD50 intravenous 8260ug/kg (8.26mg/kg)   Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972.

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