Ergonovine maleate (CAS NO.129-51-1) is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.
A deadly human poison. Experimental poison by intravenous route. Experimental reproductive effects. Human systemic effects: hypermotility, diarrhea, cyanosis, thirst, tachycardia, confusion, coma, central nervous system symptoms, gangrene; circulatory changes can follow ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also individual components. Ergonovine maleate (CAS NO.129-51-1) is one kind of dangerous material, because it has toxic by inhalation, in contact with skin and if swallowed, In case of accident or if you feel unwell, seek medical advice immediately (show label where possible). And its toxicity is:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LDLo | intravenous | 80mg/kg (80mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 398, 1935. |
infant | TDLo | intramuscular | 40ug/kg (0.04mg/kg) | GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" LUNGS, THORAX, OR RESPIRATION: CYANOSIS | JAMA, Journal of the American Medical Association. Vol. 250, Pg. 729, 1983. |
man | LDLo | unreported | 15mg/kg (15mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
mouse | LD50 | intravenous | 8260ug/kg (8.26mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972. |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View