Product Name

  • Name

    Flutropium bromide

  • EINECS 1533716-785-6
  • CAS No. 63516-07-4
  • Density
  • Solubility
  • Melting Point 192-193° (dec); mp 198-199° (dec)
  • Formula C24H29BrFNO3
  • Boiling Point
  • Molecular Weight 496.47
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, Br−, and Cl−.
  • Risk Codes
  • Molecular Structure Molecular Structure of 63516-07-4 (Flutropium bromide)
  • Hazard Symbols
  • Synonyms Flutropium Bromide;Flutropium;8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (3-Endo,8-Syn)-;8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (Endo,Syn)-;Ba 598br;Flubron;Ba 598;Flutropiumbromid;
  • PSA 46.53000
  • LogP 0.53800

Flutropium bromide Chemical Properties

Chemistry informtion about Flutropium Bromide Hydrate (CAS NO.63516-07-4) is:
IUPAC Name: Acetyloxy-[5'-(Acetyloxymercurio)-3',6'-Dihydroxy-3-Oxospiro[2-Benzofuran-1,9'-Xanthene]-4'-Yl]Mercury
Synonyms: Flutropium Bromide ; Flutropium ; 8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (3-Endo,8-Syn)- ; 8-Azoniabicyclo[3.2.1]Octane, 8-(2-Fluoroethyl)-3-[(Hydroxydiphenylacetyl)Oxy]-8-Methyl-, Bromide, (Endo,Syn)- ; Ba 598br ; Flubron ; Ba 598 ; Flutropiumbromid
Molecular Formula: C24H29BrFNO3
Molecular Weight: 478.39
Following is the molecular structure of Flutropium Bromide Hydrate (CAS NO.63516-07-4) is:

Flutropium bromide Uses

 Flutropium Bromide Hydrate (CAS NO.63516-07-4) is a quaternary ammonium antimuscarinic with bronchodilator properties that has been tried in the treatment of respiratory-tract.

Flutropium bromide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 53mg/kg (53mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
mouse LD50 intravenous 11mg/kg (11mg/kg) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea behavioral: ataxia Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
mouse LD50 oral 760mg/kg (760mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
mouse LD50 subcutaneous 228mg/kg (228mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat LD50 intraperitoneal 77mg/kg (77mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat LD50 intravenous 12500ug/kg (12.5mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.
rat LD50 oral 740mg/kg (740mg/kg) behavioral: convulsions or effect on seizure threshold behavioral: ataxia lungs, thorax, or respiration: dyspnea Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1348, 1986.
rat LD50 subcutaneous 615mg/kg (615mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 735, 1988.

Flutropium bromide Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, Br−, and Cl−.

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