• Name

  Hordenine hydrochloride

• EINECS 227-892-6
• CAS No. 6027-23-2
• Article Data4
• CAS DataBase
• Density
• Solubility
• Melting Point 178 °C
• Formula C₁₀H₁₅NO^.HCl
• Boiling Point 270.2 °C at 760 mmHg
• Molecular Weight 201.696
• Flash Point 123.5 °C
• Transport Information
• Appearance
• Safety 26-36/37/39
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Hordenine hydrochloride;Hordeninehydrochloride (6CI);Phenol, 4-[2-(dimethylamino)ethyl]-, hydrochloride (9CI);Phenol, p-[2-(dimethylamino)ethyl]-, hydrochloride (8CI);N,N-Dimethyltyraminehydrochloride;
• PSA 23.47000
• LogP 2.29830

Synthetic route

N,N-dimethyl-p-hydroxyphenylacetamide

6027-23-2

2-(4-methoxyphenyl)-N,N-dimethylethylamine hydrochloride

Conditions

Conditions	Yield
Stage #1: N,N-dimethyl-p-hydroxyphenylacetamide With sodium tetrahydroborate; boron trifluoride-tetrahydrofuran complex In tetrahydrofuran at 50 - 60℃; for 4h; Stage #2: With hydrogenchloride In tetrahydrofuran; water Concentration; Reagent/catalyst;	81.2%

34603-52-6

1-[2-(dimethylamino)ethyl]-4'-methoxy-2,3-dihydro-[1,1′-biphenyl]-4(1H)-one

6027-23-2

2-(4-methoxyphenyl)-N,N-dimethylethylamine hydrochloride

Conditions

Conditions	Yield
sublimation in the presence of NH4Cl;

6027-23-2

2-(4-methoxyphenyl)-N,N-dimethylethylamine hydrochloride

539-15-1

N,N-dimethyltyramine

Conditions

Conditions	Yield
With hydrogen bromide at 120 - 130℃;	71.54%

2105-94-4

4-bromo-2-fluorophenol

1235035-65-0

2-chloro-5-((2-trimethylsilylethoxy)methoxy)pyridine

1235036-21-1

(Z)-tert-butyl 3-(3-hydroxypropyl)-6-(8-(3-((2-(trimethylsilyl)ethoxy)methyl)benzo[d]thiazol-2(3H)-ylidenecarbamoyl)-3,4-dihydroisoquinolin-2(lH)-yl)picolinate

6027-23-2

2-(4-methoxyphenyl)-N,N-dimethylethylamine hydrochloride

1235034-29-3

6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(2-dimethylaminoethyl)phenoxy)propyl)picolinic acid

Conditions

Conditions

Yield

Stage #1: 4-bromo-2-fluorophenol; (Z)-tert-butyl 3-(3-hydroxypropyl)-6-(8-(3-((2-(trimethylsilyl)ethoxy)methyl)benzo[d]thiazol-2(3H)-ylidenecarbamoyl)-3,4-dihydroisoquinolin-2(lH)-yl)picolinate With di-tert-butyl (E)-azodicarboxylate; triphenylphosphine In tetrahydrofuran for 2h; Stage #2: 2-chloro-5-((2-trimethylsilylethoxy)methoxy)pyridine With triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide In N,N-dimethyl-formamide at 100℃; Stage #3: 2-(4-methoxyphenyl)-N,N-dimethylethylamine hydrochloride

...Expand

Hordenine hydrochloride Chemical Properties

Hordenine hydrochloride Toxicity Data With Reference

Hordenine hydrochloride Safety Profile