Imidazoline supplier | CasNO.504-75-6

Name
4,5-dihydro-1H-imidazole
EINECS
CAS No. 504-75-6
Article Data39
CAS DataBase
Density 1.15g/cm³
Solubility
Melting Point 55°C
Formula C3H6 N2
Boiling Point 219.1°Cat760mmHg
Molecular Weight 70.094
Flash Point 86.3°C
Transport Information
Appearance
Safety Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 2-Imidazoline(6CI,7CI,8CI); 4,5-Dihydroimidazole; Corban 210WS; Imidazoline; D2-Imidazoline
PSA 24.39000
LogP -0.61770

Synthetic route

: 96-45-7
N,N'-ethylenethiourea

A: 504-75-6
2-imidazoline

B: 120-93-4
imidazolidone

Conditions

Conditions	Yield
With 3,3-dimethyldioxirane In methanol; acetone at 25℃;	A 53% B 15%

: 201230-82-2
carbon monoxide

: 107-15-3
ethylenediamine

A: 504-75-6
2-imidazoline

B: 120-93-4
imidazolidone

C: 109-58-0
N-β-aminoethylcarbamic acid

Conditions

Conditions	Yield
With tetracarbonyl nickel In ethanol at 160℃; for 18h;	A 28% B 10.6% C 31.7%
With tetracarbonyl nickel In ethanol at 160℃; for 18h;	A 28% B 10.6% C 31.7%

...Expand

: 290-87-9
1,3,5-Triazine

: 107-15-3
ethylenediamine

: 504-75-6
2-imidazoline

: 96-45-7
N,N'-ethylenethiourea

A: 504-75-6
2-imidazoline

B: 120-93-4
imidazolidone

C: 64205-92-1
4,5-dihydro-1H-imidazole-2-sulfonic acid

Conditions

Conditions	Yield
With dihydrogen peroxide; trifluoroacetic acid at 25℃;

...Expand

: 504-75-6
2-imidazoline

: N-butyl-2-iodobenzamide

A: 1362191-54-5
C14H17N3O

B: 1362191-28-3
C14H15N3O

Conditions

Conditions	Yield
Stage #1: 2-imidazoline; N-butyl-2-iodobenzamide With caesium carbonate; L-proline In dimethyl sulfoxide for 0.333333h; Ullmann reaction; Inert atmosphere; Stage #2: With copper(l) iodide In dimethyl sulfoxide at 120℃; for 12h; Ullmann reaction; Inert atmosphere;	A 88% B n/a

...Expand

: 504-75-6
2-imidazoline

: 13939-06-5, 199620-15-0
molybdenum hexacarbonyl

: 64121-72-8
cis-tetracarbonylbis(2-imidazoline-N)molybdenum(0)

: 64121-75-1
fac-tricarbonyltris(2-imidazoline-N)molybdenum(0)

Conditions

Conditions	Yield
In toluene byproducts: CO; N2-atmosphere; 3 equiv. of imidazoline, 100°C, 10 min (pptn.); filtration, washing (Et2O), drying (vac.); elem. anal.; bis(imidazoline)-complex from filtrate;	A 20% B 75%

...Expand

: 504-75-6
2-imidazoline

: 177662-53-2
2-methyl-5-[4-hydroxy-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-4,5-dihydro-1H-imidazol-2-yl]pyridine

: 177660-80-9
2-methyl-5-[1-[4-(methylsulfonyl)phenyl]-4-trifluoromethyl-1H-imidazol-2-yl]pyridine

Conditions

Conditions	Yield
With p-toluenesulfonic acid monohydrate In ethyl acetate; acetone; toluene	66%

: 420-12-2
thirane

: 504-75-6
2-imidazoline

: 2-imidazolinylethanethiol

Conditions

Conditions	Yield
In toluene for 48h; Heating;	62%

: 504-75-6
2-imidazoline

: 12092-47-6
di-μ-chloro-bis(1,5-cyclooctadiene)dirhodium

: 67012-40-2
chloro(cyclo-octa-1,5-diene)(2-imidazoline-N)rhodium(I)

Conditions

Conditions	Yield
In toluene N2-atmosphere; stoich. amts., refluxing for 1 h; crystn. (-20°C), addn. of hexane, collection (filtration), washing (Et2O), drying (vac.); elem. anal.;	55%

: 504-75-6
2-imidazoline

: 177662-51-0
4-[4-hydroxy-1-[4-(methylsulfonyl) phenyl]-4-(trifluoromethyl)-4,5-dihydro-1H-imidazol-2-yl]pyridine

: 177660-79-6
4-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine

Conditions

Conditions	Yield
With p-toluenesulfonic acid monohydrate In ethyl acetate; acetone; toluene	41%

: 504-75-6
2-imidazoline

: 4702-29-8
7-methoxy-1H-isochromene-1,3(4H)-dione

: (10R,10aR)-1-[2-(2-Carboxy-4-methoxy-phenyl)-acetyl]-7-methoxy-5-oxo-1,2,3,5,10,10a-hexahydro-imidazo[1,2-b]isoquinoline-10-carboxylic acid

Conditions

Conditions	Yield
In acetonitrile at 0℃; for 2h;

: 504-75-6
2-imidazoline

: 215589-24-5
4-(4-fluorophenoxy)benzonitrile

: 299206-79-4
2-[4-(4-Fluorophenoxy)phenyl]-1H-imidazole

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydroxide; p-toluenesulfonic acid monohydrate; ethylenediamine; palladium-carbon In methanol; ethylene glycol; ethyl acetate; toluene

: 504-75-6
2-imidazoline

: 2632-14-6
4-ethylphenacyl bromide

: 1094655-78-3
1-(4-ethylphenyl)-2-imidazolylethan-1-one

Conditions

Conditions	Yield
In acetonitrile

: 504-75-6
2-imidazoline

CH3: CH3

: 121-44-8
triethylamine

: 288-32-4
1H-imidazole

Conditions

Conditions	Yield
With manganese dioxide In dichloromethane; chloroform	370 mg (76%)
With manganese dioxide In dichloromethane; chloroform	370 mg (76%)

...Expand

: 504-75-6
2-imidazoline

: 4-[2-Imidazolin-2-yl]-6-(2-chlorophenyl)-2,3,4,5-tetrahydro-8H-[1]benzothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 74-88-4
methyl iodide

: 4-[1-Methyl-2-imidazolin-2-yl]-6-(2-chlorophenyl)-2,3,4,5-tetrahydro-8H-[1]benzothieno[3,2-f][1,2,4]triazolo [4,3-a][1,4]diazepine

Conditions

Conditions	Yield
In tetrahydrofuran

...Expand

: 504-75-6
2-imidazoline

: 189297-36-7
3-methyl-6-[4-hydroxy-1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-4,5-dihydro-1H-imidazol-2-yl]pyridine

: 177660-82-1
5-methyl-2-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine

Conditions

Conditions	Yield
With p-toluenesulfonic acid monohydrate In toluene

: 504-75-6
2-imidazoline

: 26787-78-0
amoxicillin

: N-[6-[[2-(acetylamino)-1-oxopropyl]amino]-1,4-dihydro-4-oxo-3-quinolinylcarbonyl]amoxicillin

Conditions

Conditions	Yield
With sodium hydroxide; triethylamine In N,N-dimethyl acetamide; water

: 504-75-6
2-imidazoline

: 87604-75-9
1-acetyl-2-imidazoline

Conditions

Conditions	Yield
In ethanol; acetic anhydride
In ethanol; acetic anhydride
In ethanol; acetic anhydride

Imidazoline Chemical Properties

IUPAC: 4,5-Dihydro-1H-imidazole
Imidazoline with CAS NO. of 504-75-6 is also called for 2-Imidazoline ; 4,5-Dihydro-1H-imidazole ; 1H-Imidazole, 4,5-dihydro- ; CHEBI:53094 ; CID68156 ; EINECS 207-999-4 ; 504-75-6 and so on.
Molecular Weight: 70.09
Molecular Formula: C₃H₆N₂
ACD/LogP: -1.08
ACD/LogD (pH 5.5): -3.08
ACD/LogD (pH 7.4): -3.07
ACD/BCF (pH 5.5): 1
ACD/BCF (pH 7.4): 1
ACD/KOC (pH 5.5): 1
ACD/KOC (pH 7.4): 1
H bond acceptors: 2
H bond donors: 1
Freely Rotating Bonds: 0
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 48.9
Isotope Atom Count: 0
Defined Atom StereoCenter Count: 0
Undefined Atom StereoCenter Count: 0
Defined Bond StereoCenter Count: 0
Undefined Bond StereoCenter Count: 0
Covalently-Bonded Unit Count: 1
Index of Refraction: 1.568
Molar Refractivity: 19.92 cm³
Molar Volume: 60.8 cm³
Surface Tension: 41.8 dyne/cm
Density: 1.15 g/cm³
Flash Point: 86.3°C
Enthalpy of Vaporization: 45.55 kJ/mol
Boiling Point: 219.1°C at 760 mmHg
Vapour Pressure: 0.122 mmHg at 25°C
The molecular structure of Imidazoline with CAS NO. of 504-75-6 :

Imidazoline Uses

Imidazoline (CAS NO.504-75-6) is found in the commercially available second generation Grubbs' catalyst.

Imidazoline Toxicity Data With Reference

ipr-mus LD50:50 mg/kg

AMRL** Aerospace Medical Research Laboratory Report.(Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)

Imidazoline Consensus Reports

Reported in EPA TSCA Inventory.

Imidazoline Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x.

Imidazoline Specification

1.Removal in wastewater treatment of Imidazoline (CAS NO.504-75-6):
Total removal:1.87 percent
Total biodegradation:0.09 percent
Total sludge adsorption:1.76 percent
Total to air:0.03 percent
(using 10000 hr Bio P,A,S)
2. Imidazoline (CAS NO.504-75-6) is a nitrogen-containing heterocycle which is derived from imidazole.The ring contains an imine bond, and the carbons at the 4 and 5 positions are singly bonded, rather than doubly bonded for the case of imidazole.

Product Name

4,5-dihydro-1H-imidazole

Synthetic route

Imidazoline Chemical Properties

Imidazoline Uses

Imidazoline Toxicity Data With Reference

Imidazoline Consensus Reports

Imidazoline Safety Profile

Imidazoline Specification

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