-
Name
wofapyrin
- EINECS
- CAS No. 8064-79-7
- Density g/cm3
- Solubility
- Melting Point
- Formula C19H20N2O2•C13H17N3O
- Boiling Point 424.9°Cat760mmHg
- Molecular Weight 539.74
- Flash Point 174.3°C
- Transport Information
- Appearance
- Safety Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and intramuscular routes. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Wofapyrin;Pabialgin;Irgapyrine;Rheopyrine;Irgapyrin;
- PSA 70.79000
- LogP 5.46820
Irgapyrin Chemical Properties
IUPAC Name: 4-Butyl-1,2-diphenylpyrazolidine-3,5-dione ; 4-(dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one
Synonyms of Irgapyrin (CAS NO.8064-79-7) : 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, mixed with 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ; Irgapyrin ; Irgapyrine ; Pabialgin ; Rheopyrine ; Wofapyrin
CAS NO:8064-79-7
Molecular Formula:C32H37N5O3
Molecular Weight :539.6679
Molecular Structure :.png)
Flash Point: 174.3 °C
Enthalpy of Vaporization: 67.94 kJ/mol
Boiling Point: 424.9 °C at 760 mmHg
Vapour Pressure: 2E-07 mmHg at 25°C
Irgapyrin Uses
Irgapyrin (CAS NO.8064-79-7) is used as intermediate in organic synthesis.
Irgapyrin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intramuscular | 560mg/kg (560mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 79, 1977. | |
| mouse | LD50 | intraperitoneal | 412mg/kg (412mg/kg) | Dissertationes Pharmaceuticae et Pharmacologicae. Vol. 23, Pg. 363, 1971. | |
| mouse | LD50 | intravenous | 155mg/kg (155mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 387, 1953. |
| mouse | LD50 | oral | 700mg/kg (700mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Schweizerische Medizinische Wochenschrift. Vol. 79, Pg. 577, 1949. |
| rabbit | LD50 | intravenous | 145mg/kg (145mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Schweizerische Medizinische Wochenschrift. Vol. 79, Pg. 577, 1949. |
| rat | LD50 | intraperitoneal | 290mg/kg (290mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 387, 1953. |
| rat | LD50 | intravenous | 160mg/kg (160mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Schweizerische Medizinische Wochenschrift. Vol. 79, Pg. 577, 1949. |
| rat | LD50 | oral | 1375mg/kg (1375mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Schweizerische Medizinische Wochenschrift. Vol. 79, Pg. 577, 1949. |
Irgapyrin Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and intramuscular routes. When Irgapyrin (CAS NO.8064-79-7) is heated to decomposition ,it emits toxic fumes of NOx.
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