Product Name

  • Name

    Isepamicine

  • EINECS 261-143-4
  • CAS No. 58152-03-7
  • Article Data2
  • CAS DataBase
  • Density 1.53g/cm3
  • Solubility
  • Melting Point
  • Formula C22H43 N5 O12
  • Boiling Point 926.8°Cat760mmHg
  • Molecular Weight 569.61
  • Flash Point 514.3°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 58152-03-7 (Isepamicine)
  • Hazard Symbols
  • Synonyms D-Streptamine,O-6-amino-6-deoxy-a-D-glucopyranosyl-(1®4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(1®6)]-N1-(3-amino-2-hydroxy-1-oxopropyl)-2-deoxy-, (S)-;HAPA-B; Isepamicin; Isepamicine; Sch 21420
  • PSA 297.72000
  • LogP -4.64170

Isepamicine Chemical Properties

Product Name: Isepamicine
The MF of Isepamicine (CAS NO.58152-03-7) is C22H43N5O12.

           
The MW of Isepamicine (CAS NO.58152-03-7) is 569.6.
Synonyms of Isepamicine (CAS NO.58152-03-7): (s)-Y-1-Oxopropyl)-2-deoxy ; Hapa-b ; Hapa-gentamycinb ; Isepamicin ; Sch21420 ; Thyl-3-(methylamino)-beta-l-arabinopyranosyl-(1-6))-n(sup1)-(3-amino-2-hydrox ; (S)-O-6-Amino-6-deoxy-alpha-D-glucopyranosyl-(1->4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1->6)]-1,3-diamino-N1-(3-aminolactoyl)-1,2,3-trideoxy-D-scyllo-inositol
Index of Refraction: 1.641 
EINECS: 261-143-4 
Density: 1.53 g/ml
Flash Point: 514.3 °C
Boiling Point: 926.8 °C

Isepamicine Uses

  Isepamicine (CAS NO.58152-03-7) is semi-synthetic aminoglycoside antibiotics used for Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and other susceptible ones caused by sepsis, chronic bronchitis, bronchiectasis, infection, pneumonia, peritonitis and so on.

Isepamicine Production

Raw materials Ammonium hydroxide-->Trifluoroacetic acid-->Isepamicin sulfate
 

Isepamicine Toxicity Data With Reference

1.    

ipr-mus LD50:5000 mg/kg

     DRFUD4    Drugs of the Future. 4 (1979),525.
2.    

ivn-mus LD50:330 mg/kg

     DRFUD4    Drugs of the Future. 4 (1979),525.

Isepamicine Safety Profile

Poison by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.

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