Product Name

  • Name

    (-)-ANABASINE

  • EINECS 207-791-3
  • CAS No. 494-52-0
  • Article Data22
  • CAS DataBase
  • Density 1.054
  • Solubility
  • Melting Point 9°C
  • Formula C10H14 N2
  • Boiling Point 271 °C at 760 mmHg
  • Molecular Weight 162.235
  • Flash Point 93 ºC
  • Transport Information 3140
  • Appearance White fine crystalline powder
  • Safety Poison by ingestion, subcutaneous, and intravenous routes. Moderately toxic by skin contact. An experimental teratogen. Insecticide. Acute and subacute toxicity: increased salivation, vertigo, confusion, disturbed vision and hearing, photophobia, cold extremities, nausea, vomiting, diarrhea, syncope, colonic spasms. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes R23/24/25   
  • Molecular Structure Molecular Structure of 494-52-0 ((-)-ANABASINE)
  • Hazard Symbols
  • Synonyms Anabasine(8CI); Pyridine, 3-(2-piperidinyl)-, (S)-; (-)-2-(3'-Pyridyl)piperidine;(-)-Anabasine; (2S)-2-(Pyridin-3-yl)piperidine; (S)-(-)-Anabasine;(S)-Anabasine; Anabasin; NSC 87504; Neonicotine; Neonikotin
  • PSA 24.92000
  • LogP 2.22500

L-(-)-Anabasine Chemical Properties

MF: C10H14N2
MW: 162.23
EINECS: 207-791-3
mp：  9°C
bp：  270-272°C
density：  1,0455 g/cm3
refractive index：  1.5430
Fp：  93°C
Merck：  14,619
BRN：  82637
CAS DataBase Reference： 494-52-0(CAS DataBase Reference)
NIST Chemistry Reference： 494-52-0(NIST)
The structure of ANABASINE is: 

         


 

L-(-)-Anabasine Uses

1、Anabasine is a pyridine alkaloid found in the Tree Tobacco (Nicotiana glauca) plant, a close relative of the common tobacco plant (Nicotiana tabacum). It is similar to nicotine. Its principal (historical) industrial use is as an insecticide.
2、Anabasine is present in trace amounts in tobacco smoke, and can be used as an indicator of a person's exposure to tobacco smoke.

 

L-(-)-Anabasine Toxicity Data With Reference

1、RTECS#: CAS# 494-52-0: BV4375000
2、LD50/LC50: RTECS: Not available. 
3、Carcinogenicity: L(-)-Anabasine - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
4、Other: The toxicological properties have not been fully investigated. Experimental teratogen. See actual entry in RTECS for complete information. 
   		      
   

 

    
   

 

    
   

 

    

L-(-)-Anabasine Safety Profile

Hazard Codes：  T
Risk Statements： Very Toxic in contact with skin；Very Toxic if swallowed
Safety Statements： Wear suitable protective clothing；Wear suitable gloves
RIDADR：  3140
RTECS：  BV4375000
HazardClass：  6.1
PackingGroup：  I
Hazardous Substances Data： 494-52-0(Hazardous Substances Data)
Poison by ingestion, subcutaneous, and intravenous routes. Moderately toxic by skin contact. An experimental teratogen. Insecticide. Acute and subacute toxicity: increased salivation, vertigo, confusion, disturbed vision and hearing, photophobia, cold extremities, nausea, vomiting, diarrhea, syncope, colonic spasms. When heated to decomposition it emits toxic fumes of NOx.

L-(-)-Anabasine Specification

1、Fire Fighting Measures 
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustible liquid. 
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
2、Handling and Storage 
Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. 
Storage: Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. 

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