Product Name

  • Name

    L-AP4

  • EINECS 200-258-5
  • CAS No. 23052-81-5
  • Article Data12
  • CAS DataBase
  • Density 1.628g/cm3
  • Solubility Soluble to 5 mM in water and to 100 mM in 1eq. NaOH
  • Melting Point 207-215 ºC
  • Formula C4H10 N O5 P
  • Boiling Point 491.7°Cat760mmHg
  • Molecular Weight 183.101
  • Flash Point 251.2°C
  • Transport Information
  • Appearance white to off-white crystalline powder
  • Safety 26-36
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 23052-81-5 (L-AP4)
  • Hazard Symbols IrritantXi
  • Synonyms Butanoicacid, 2-amino-4-phosphono-, (S)-; Butyric acid, 2-amino-4-phosphono-, L- (8CI);(S)-2-Amino-4-phosphonobutanoic acid; L-(+)-2-Amino-4-phosphonobutyric acid;L-2-Amino-4-phosphonobutanoic acid; L-2-Amino-4-phosphonobutyric acid; L-AP 4;L-APB; S-(+)-2-Amino-4-phosphonobutanoic acid
  • PSA 130.66000
  • LogP -0.33360

L-AP4 Chemical Properties

IUPAC Name: (2S)-2-amino-4-phosphonobutanoic acid
Synonyms: (2S)-2-Amino-4-phosphonobutanoic acid ; Butanoic acid, 2-amino-4-phosphono-, (2S)- ; (S)-2-Amino-4-phosphonobutanoic acid ; (S)-2-Amino-4-phosphono-butyric acid ; 2-Amino-4-phosphonobutanoic acid ; 2-Amino-4-phosphonobutyric acid ; 2-Amino-4-phosphono-butyric acid ; 2-Amino-4-phosphono-butyric acid(S-AP4) ; L-(+)-2-Amino-4-phosphonobutyric acid 
CAS NO: 23052-81-5
Molecular Formula of L-AP4 (CAS NO.23052-81-5) : C4H10NO5P
Molecular Weight of L-AP4 (CAS NO.23052-81-5) : 183.1
Molecular Structure of L-AP4 (CAS NO.23052-81-5) :
Product Categories: Glutamate receptor
Mol File: 23052-81-5.mol
Index of Refraction: 1.545
Surface Tension: 88.8 dyne/cm
Density: 1.628 g/cm3
Flash Point: 251.2 °C
Enthalpy of Vaporization: 83.05 kJ/mol
Boiling Point: 491.7 °C at 760 mmHg
Vapour Pressure: 5.18E-11 mmHg at 25°C
Melting point: 207-215 °C
Storage temp. 0-6°C
Appearance:white to off-white crystalline powder

L-AP4 Uses

 L-AP4 (CAS NO.23052-81-5) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors, but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions.

L-AP4 Safety Profile

Hazard Codes IrritantXi
Risk Statements 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany 3

L-AP4 Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a tightly closed container. Keep refrigerated. (Store below 4°C/39°F.)

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