Product Name

  • Name

    LEUPEPTIN

  • EINECS
  • CAS No. 24365-47-7
  • Article Data3
  • CAS DataBase
  • Density 1.21g/cm3
  • Solubility
  • Melting Point
  • Formula C20H38 N6 O4
  • Boiling Point °Cat760mmHg
  • Molecular Weight 426.56
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 24365-47-7 (LEUPEPTIN)
  • Hazard Symbols
  • Synonyms Valeramide,2-(2-acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methyl-(8CI);Acetyl-L-leucyl-L-leucylargininal;Leupeptin Ac-LL;
  • PSA 166.27000
  • LogP 2.37870

Leupeptin ac-ll Chemical Properties

IUPAC Name: 2-[[(2S)-2-Acetamido-4-methylpentanoyl]amino]-N-[5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Molecular Formula: C20H38N6O4
Molecular Weight: 426.64g/mol
Density:1.21g/cm3
Freely Rotating Bonds: 14
Polar Surface Area: 96.84 Å2
Index of Refraction: 1.557
Molar Refractivity: 113.24 cm3
Molar Volume: 351.5 cm3
Polarizability: 44.89× 10-24cm3
Surface Tension: 43.9 dyne/cm
The Cas Register Number of Leupeptin ac-ll is 24365-47-7 .The chemical synonyms of Leupeptin ac-ll (CAS No.24365-47-7) are 2-(2-Acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-methylval ; 2-(2-Acetamido-4-methylvaleramido)-n-(1-formyl-4-guanidinobutyl)-4-valeramid ; Leupeptinac-ll ; L-Leucinamide,n-acetyl-l-leucyl-n-(4-((aminoiminomethyl)amino)-1-formylbutyl ; N-Acetyl-l-leucyl-l-leucyl-l-argininal ; NK-381 ; AC-llr-cho ; Ac-leu-leu-arg-cho .The molecular structure of Leupeptin ac-ll (CAS No.24365-47-7) is.

Leupeptin ac-ll Toxicity Data With Reference

1.    

orl-rat LD50:720 mg/kg

     JZKEDZ    Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 3 (1977),9.
2.    

scu-rat LD50:1100 mg/kg

     JZKEDZ    Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 3 (1977),9.
3.    

ivn-rat LD50:80 mg/kg

     JZKEDZ    Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 3 (1977),9.
4.    

orl-mus LD50:740 mg/kg

     JZKEDZ    Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 3 (1977),9.
5.    

scu-mus LD50:540 mg/kg

     JZKEDZ    Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 3 (1977),9.
6.    

ivn-mus LD50:74 mg/kg

     JZKEDZ    Jitchuken, Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Preclinical Reports. 3 (1977),9.

Leupeptin ac-ll Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.

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