Product Name

  • Name

    Levoxadrol

  • EINECS
  • CAS No. 23257-58-1
  • Density g/cm3
  • Solubility
  • Melting Point 248-254 °C
  • Formula C20H23 N O2 . Cl H
  • Boiling Point 468.4°Cat760mmHg
  • Molecular Weight 345.90
  • Flash Point 237.1°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 23257-58-1 (Levoxadrol)
  • Hazard Symbols
  • Synonyms Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-, hydrochloride (8CI); Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-, hydrochloride, [R-(R*,R*)]-; Piperidine,2-[(4R)-2,2-diphenyl-1,3-dioxolan-4-yl]-, hydrochloride, (2R)- (9CI); CL 912C;Levoxadrol hydrochloride; Levoxan; NIH 10374; NSC 526062; NSC 526063
  • PSA 30.49000
  • LogP 4.57600

Levoxadrol hydrochloride Chemical Properties

Molecular Structure of Levoxadrol hydrochloride (CAS NO. 23257-58-1):

IUPAC Name: (2R)-2-Methyl-2-[(4R)-4-methyl-2,2-diphenyl-1,3-dioxolan-4-yl]piperidine hydrochloride  
Molecular Formula: C22H28ClNO2
Molecular Weight: 373.916220 g/mol
H-Bond Donor: 2
H-Bond Acceptor: 3
Canonical SMILES: CC1(CCCCN1)C2(COC(O2)(C3=CC=CC=C3)C4=CC=CC=C4)C.Cl
Isomeric SMILES: C[C@@]1(CCCCN1)[C@@]2(COC(O2)(C3=CC=CC=C3)C4=CC=CC=C4)C.Cl
InChI: InChI=1S/C22H27NO2.ClH/c1-20(15-9-10-16-23-20)21(2)17-24-22(25-21,18-11-5-3-6-12-18)19-13-7-4-8-14-19;/h3-8,11-14,23H,9-10,15-17H2,1-2H3;1H/t20-,21+;/m1./s1
InChIKey: FAVXTRMOUJUBQT-BHDTVMLSSA-N
Flash Point: 237.1 °C
Enthalpy of Vaporization: 74.45 kJ/mol
Boiling Point: 468.4 °C at 760 mmHg
Vapour Pressure of Levoxadrol hydrochloride (CAS NO. 23257-58-1): 3.6E-09 mmHg at 25 °C

Levoxadrol hydrochloride Toxicity Data With Reference

1.    

orl-rat LD50:310 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 153 (1965),105.
2.    

orl-mus LD60:230 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 153 (1965),105.
3.    

ivn-rbt LD50:25 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 153 (1965),105.

Levoxadrol hydrochloride Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and HCl.

Levoxadrol hydrochloride Specification

  Levoxadrol hydrochloride with cas registry number of 23257-58-1 is also known as (-)-2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine hydrochloride ; CL 912C ; Levoxadrol HCl ; Levoxadrol hydrochloride [USAN] ; Levoxan ; NSC 526063 ; Relane ; U 22559A ; U-22,304A ; UNII-3ARD9VMM81 ; l-2,2-Diphenyl-4-(2-piperidyl)-1,3-dioxolane hydrochloride ; l-2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine hydrochloride ; l-Dioxadrol hydrochloride ; Piperidine, 2-(2,2-diphenyl-1,3-dioxolan-4-yl)-, hydrochloride ; Piperidine, 2-(2,2-diphenyl-1,3-dioxolan-4-yl)-, hydrochloride, l- .

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