The Sequence of Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (CAS NO.163913-87-9): Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys
Molecular Formula: C118H177N35O29S
Molecular Weight: 2581.98
Appearance: White to off-white powder
Solubility: <1mg/ml soluble in water, methanol, DMSO or dimethyl formamide
Storage: Store at -20°C. Recommended to reconstitute the lyophilized MOG in sterile 18 MΩ-cm H2O of not less than 100 µg/ml. This solution can then be further diluted to other aqueous solutions.
Safety Statements: 22-24/25
S22: Do not breathe dust
S24/25: Avoid contact with skin and eyes
Myelin oligodendrocyte glycoprotein (MOG) is found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes and has been implicated as an important autoantigen in multiple sclerosis (MS). This peptide induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice.
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