IUPAC Name: [(2R,3S,4S,5R)-3,4-Dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl]methanesulfonate
Empirical Formula of Mannosulfan (CAS NO.7518-35-6): C10H22O14S4
Molecular Weight: 494.5333 g/mol
Index of Refraction: 1.536
Density: 1.65 g/cm3
Flash Point: 482.3 °C
Enthalpy of Vaporization: 144.28 kJ/mol
Boiling Point: 873.8 °C at 760 mmHg
Structure of Mannosulfan (CAS NO.7518-35-6):
Mannosulfan (CAS NO.7518-35-6) is an alkylating agent used in the treatment of cancer.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 1730mg/kg (1730mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 961, 1973. | |
mouse | LD50 | oral | > 5gm/kg (5000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 961, 1973. | |
mouse | LD50 | unreported | 2300mg/kg (2300mg/kg) | Therapia Hungarica. Vol. 19, Pg. 10, 1971. | |
rat | LD50 | intraperitoneal | 2300mg/kg (2300mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 961, 1973. | |
rat | LD50 | oral | > 5gm/kg (5000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 961, 1973. | |
rat | LD50 | unreported | 2gm/kg (2000mg/kg) | Therapia Hungarica. Vol. 19, Pg. 10, 1971. |
Moderately toxic by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES.
Mannosulfan , its cas register number is 7518-35-6. It also can be called 1,2,5,6-Tetramesyl-D-mannitol ; Tetra-o-methyl-sulphonyl-D-mannitol ; and D-Mannitol 1,2,5,6-tetramethanesulfonate .
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