Product Name: Monomycin
CAS NO:54597-56-7
Classification Code : Drug / Therapeutic Agent ;Natural Product
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LDLo | subcutaneous | 600mg/kg (600mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA GASTROINTESTINAL: NAUSEA OR VOMITING | Antibiotiki. Vol. 5(4), Pg. 10, 1960. |
mouse | LD | oral | > 2gm/kg (2000mg/kg) | Antibiotiki. Vol. 5(4), Pg. 10, 1960. | |
mouse | LD50 | intraperitoneal | 510mg/kg (510mg/kg) | "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 433, 1967. | |
mouse | LD50 | intravenous | 77mg/kg (77mg/kg) | Archivum Immunologiae et Therapiae Experimentalis. Vol. 10, Pg. 947, 1962. | |
mouse | LD50 | subcutaneous | 615mg/kg (615mg/kg) | "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 433, 1967. | |
rabbit | LDLo | intravenous | 250mg/kg (250mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITH APPROPRIATE ANESTHESIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA | Antibiotiki. Vol. 5(4), Pg |
Poison by intravenous route. Monomycin (CAS NO:54597-56-7) is moderately toxic by intraperitoneal and subcutaneous routes.
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