Product Name

  • Name

    N-(Benzyloxycarbonyloxy)succinimide

  • EINECS 236-075-3
  • CAS No. 13139-17-8
  • Article Data25
  • CAS DataBase
  • Density 1.38 g/cm3
  • Solubility acetone: 0.1 g/mL, clear
  • Melting Point 80-82 °C(lit.)
  • Formula C12H11NO5
  • Boiling Point 369 °C at 760 mmHg
  • Molecular Weight 249.223
  • Flash Point 177 °C
  • Transport Information
  • Appearance white crystal powde
  • Safety 22-24/25-36-26
  • Risk Codes 43-24/25-36/37/38-20/21/22
  • Molecular Structure Molecular Structure of 13139-17-8 (N-(Benzyloxycarbonyloxy)succinimide)
  • Hazard Symbols IrritantXi,HarmfulXn
  • Synonyms Succinimide, N-(carboxyoxy)-, benzyl ester(8CI);1-[[(Benzyloxy)carbonyl]oxy]-2,5-pyrrolidinedione;Benzyl2,5-dioxopyrrolid-1-yl carbonate;Benzyl N-succinimidyl carbonate;Benzyl succinimidyl carbonate;N-(N-Benzyloxycarbonyloxy)succinimide;N-Benzyloxycarbonyloxysuccinamide;Benzyloxycarbonyloxysuccinimide;Z-OSu;Cbz-OSu;
  • PSA 72.91000
  • LogP 1.34170

Synthetic route

1-hydroxy-pyrrolidine-2,5-dione
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

benzyl chloroformate
501-53-1

benzyl chloroformate

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; ethyl acetate at 15℃; for 19h; Large scale;90.5%
With TEA In 1,2-dimethoxyethane25%
With triethylamine In acetonitrile at 5℃; for 1h;
dicyclohexylamine salt of N-hydroxysuccinimide
82911-72-6

dicyclohexylamine salt of N-hydroxysuccinimide

benzyl chloroformate
501-53-1

benzyl chloroformate

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

Conditions
ConditionsYield
In chloroform90%
succinic acid anhydride
108-30-5

succinic acid anhydride

benzyl chloroformate
501-53-1

benzyl chloroformate

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

Conditions
ConditionsYield
Stage #1: succinic acid anhydride With hydroxylamine sulfate In water Alkaline conditions;
Stage #2: With phosphoric acid In water; toluene Reflux; Alkaline conditions;
Stage #3: benzyl chloroformate In toluene for 2h; Reagent/catalyst;		52.7%
di(succinimido) carbonate
74124-79-1

di(succinimido) carbonate

benzyl alcohol
100-51-6

benzyl alcohol

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

Conditions
ConditionsYield
With triethylamine In acetonitrile at 20℃; Substitution;
With triethylamine In acetonitrile at 20℃; for 0.75 - 1h; Product distribution / selectivity;
N-cyclohexyl-cyclohexanamine
101-83-7

N-cyclohexyl-cyclohexanamine

chromium oxide activated nickel catalyst

chromium oxide activated nickel catalyst

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 95 percent / acetone
2: 90 percent / CHCl3
View Scheme
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

5-Carbamimidoyl-1H-indole-2-carboxylic acid ethyl ester
199609-28-4

5-Carbamimidoyl-1H-indole-2-carboxylic acid ethyl ester

5-(Benzyloxycarbonylamino-imino-methyl)-1H-indole-2-carboxylic acid ethyl ester
199609-35-3

5-(Benzyloxycarbonylamino-imino-methyl)-1H-indole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide Ambient temperature;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

ethanolamine
141-43-5

ethanolamine

benzyl 2-hydroxyethylcarbamate
77987-49-6

benzyl 2-hydroxyethylcarbamate

Conditions
ConditionsYield
With sodium carbonate In water; acetone at 20℃; for 4h;100%
With TEA In tetrahydrofuran for 5h;92%
In 1,4-dioxane; water for 12h;89%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

5-hydroxypentylamine
2508-29-4

5-hydroxypentylamine

5-<(benzyloxycarbonyl)amino>pentanol
87905-98-4

5-<(benzyloxycarbonyl)amino>pentanol

Conditions
ConditionsYield
With sodium hydroxide In water; acetone at 20℃; for 4h;100%
In tetrahydrofuran at 20℃; for 19h; Acylation;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

(2S)-2-(2-methoxyethyl)piperidine
103639-57-2

(2S)-2-(2-methoxyethyl)piperidine

benzyl (2S)-2-(2-hydroxyethyl)piperidine-1-carboxylate
190967-63-6

benzyl (2S)-2-(2-hydroxyethyl)piperidine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 23℃; for 18h;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

4-Aminobutanol
13325-10-5

4-Aminobutanol

benzyl 4-hydroxybutylcarbamate
17996-13-3

benzyl 4-hydroxybutylcarbamate

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetone at 20℃; for 4h;100%
With triethylamine In acetone at 20℃; for 7h;92.8%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

D-allylglycine
54594-06-8

D-allylglycine

(R)-2-(benzyloxycarbonylamino)pent-4-enoic acid
127474-54-8

(R)-2-(benzyloxycarbonylamino)pent-4-enoic acid

Conditions
ConditionsYield
With water; triethylamine In 1,4-dioxane at 20℃;100%
With triethylamine In tetrahydrofuran; water at 20℃;76%
With sodium hydroxide; sodium hydrogencarbonate In 1,4-dioxane; water at 0℃;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

L-allylglycine
16338-48-0

L-allylglycine

(S)-2-(benzyloxycarbonylamino)pent-4-enoic acid
78553-51-2

(S)-2-(benzyloxycarbonylamino)pent-4-enoic acid

Conditions
ConditionsYield
With water; triethylamine In 1,4-dioxane100%
Stage #1: N-(Benzyloxycarbonyloxy)succinimide; L-allylglycine With sodium hydroxide In water; acetone
Stage #2: With sodium hydrogencarbonate In water; acetone for 20h;		95%
With sodium hydroxide; sodium hydrogencarbonate In 1,4-dioxane; water at 0℃;
6-amino-2-hydroxymethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester

6-amino-2-hydroxymethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

(2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol
916763-94-5

(2R,1'S,3S,4S)-Nα-Boc-3,4-(Z-aminomethano)prolinol

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetone for 3h;100%
4-[(3-amino-2-hydroxypropyl)oxy]benzonitrile
227940-77-4

4-[(3-amino-2-hydroxypropyl)oxy]benzonitrile

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

benzyl 3-(4-cyanophenoxy)-2-hydroxypropylcarbamate

benzyl 3-(4-cyanophenoxy)-2-hydroxypropylcarbamate

Conditions
ConditionsYield
With triethylamine In chloroform at 0 - 20℃;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

L-tert-Leucine
20859-02-3

L-tert-Leucine

(S)-N-carbobenzoxy-tert-butylleucine
62965-10-0

(S)-N-carbobenzoxy-tert-butylleucine

Conditions
ConditionsYield
With triethylamine In methanol at 20℃; for 14h;100%
1,2,3,6-tetrahydropyridine
694-05-3

1,2,3,6-tetrahydropyridine

N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

1-benzyloxycarbonyl-1,2,3,6-tetrahydropyridine
66207-23-6

1-benzyloxycarbonyl-1,2,3,6-tetrahydropyridine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃;100%
With triethylamine In dichloromethane at 20 - 30℃; for 16h;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate
773826-73-6

tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate

1,1-dimethylethyl 3-hydroxy-4-[({[(phenylmethyl)oxy]carbonyl}amino)methyl]-1-pyrrolidinecarboxylate
872716-50-2

1,1-dimethylethyl 3-hydroxy-4-[({[(phenylmethyl)oxy]carbonyl}amino)methyl]-1-pyrrolidinecarboxylate

Conditions
ConditionsYield
In dichloromethane at 0℃; for 1h;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

3-methyl-piperazine-1-carboxylic acid tert-butyl ester
120737-59-9

3-methyl-piperazine-1-carboxylic acid tert-butyl ester

O-benzyl carbamate
621-84-1

O-benzyl carbamate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane; water100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

diisopropylethylamine (DIPEA)

diisopropylethylamine (DIPEA)

(S)-methyl pipecolinate hydrochloride
18650-39-0

(S)-methyl pipecolinate hydrochloride

(S)-1-(Benzyloxycarbonyl)-2-piperidine-carboxylic Acid Methyl Ester
60369-19-9, 60343-61-5

(S)-1-(Benzyloxycarbonyl)-2-piperidine-carboxylic Acid Methyl Ester

Conditions
ConditionsYield
In dichloromethane (DCM); hexane; ethyl acetate100%
...Expand
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

2-amino-2-methylpropanesulfonic acid sodium salt
60155-08-0

2-amino-2-methylpropanesulfonic acid sodium salt

sodium 2-(benzyloxycarbonylamino)-2-methylpropane-1-sulfonate
1037833-06-9

sodium 2-(benzyloxycarbonylamino)-2-methylpropane-1-sulfonate

Conditions
ConditionsYield
In tetrahydrofuran; water at 20℃; for 16h;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

3',4'-dideoxy-2-hydroxyneamine dicarbonate

3',4'-dideoxy-2-hydroxyneamine dicarbonate

1,3,2',6'-tetra-N-benzyloxycarbonyl-3',4'-dideoxy-2-hydroxyneamine
959918-76-4

1,3,2',6'-tetra-N-benzyloxycarbonyl-3',4'-dideoxy-2-hydroxyneamine

Conditions
ConditionsYield
With triethylamine In 1,2-dimethoxyethane; water at 45℃; Product distribution / selectivity;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

1,4,7,10-tetraazacyclododecan
294-90-6

1,4,7,10-tetraazacyclododecan

1,4,7,10-tetraaza-cyclododecane-1,7-dicarboxylic acid dibenzyl ester
162148-45-0

1,4,7,10-tetraaza-cyclododecane-1,7-dicarboxylic acid dibenzyl ester

Conditions
ConditionsYield
In chloroform at 20℃; for 48h;100%
In chloroform at 20℃; for 0.5h; Inert atmosphere;100%
In chloroform at 20℃; for 48h;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

tert-butyl (3R,4R)-N-tert-butyloxycarbonyl-4-aminopyrrolidine-3-carboxylate
797038-63-2

tert-butyl (3R,4R)-N-tert-butyloxycarbonyl-4-aminopyrrolidine-3-carboxylate

(3R,4R)-di-tert-butyl 4-(benzyloxycarbonylamino)pyrrolidine-1,3-dicarboxylate
1033881-73-0

(3R,4R)-di-tert-butyl 4-(benzyloxycarbonylamino)pyrrolidine-1,3-dicarboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 3h;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

D-phenylalanine ester
756458-80-7

D-phenylalanine ester

JM 3459-130

JM 3459-130

Conditions
ConditionsYield
With 4-methyl-morpholine In dichloromethane at 0 - 20℃;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

3,3'-Diamino-N-methyldipropylamine
105-83-9

3,3'-Diamino-N-methyldipropylamine

C23H31N3O4
1307864-23-8

C23H31N3O4

Conditions
ConditionsYield
In chloroform at 20℃; for 16h;100%
In chloroform at 20℃; for 16h;
In chloroform at 20℃; for 16h;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

N,N-dimethylethylenediamine
108-00-9

N,N-dimethylethylenediamine

(2-dimethylamino-ethyl)-carbamic acid benzyl ester

(2-dimethylamino-ethyl)-carbamic acid benzyl ester

Conditions
ConditionsYield
In chloroform at 0 - 20℃; for 2h; Inert atmosphere;100%
In chloroform at 0 - 20℃; for 2h; Inert atmosphere;
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

C30H51N3O5
1376616-31-7

C30H51N3O5

(1S,2S,4S)-4-(2-carbamoyl-2-methylpropyl-carbamoyl)-2-hydroxy-1-{(S)-2-[4-methoxy-3-(3-methoxypropoxy)-benzyl]-3-methylbutyl}-5-methylhexyl-carbamic acid benzyl ester
1236549-06-6

(1S,2S,4S)-4-(2-carbamoyl-2-methylpropyl-carbamoyl)-2-hydroxy-1-{(S)-2-[4-methoxy-3-(3-methoxypropoxy)-benzyl]-3-methylbutyl}-5-methylhexyl-carbamic acid benzyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 1h;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

1-tert-butyl 2-methyl (2S,4S)-4-(aminomethyl)pyrrolidine-1,2-dicarboxylate

1-tert-butyl 2-methyl (2S,4S)-4-(aminomethyl)pyrrolidine-1,2-dicarboxylate

1-tert-butyl 2-methyl (2S,4S)-4-({[(benzyloxy)carbonyl]amino}methyl)pyrrolidine-1,2-dicarboxylate

1-tert-butyl 2-methyl (2S,4S)-4-({[(benzyloxy)carbonyl]amino}methyl)pyrrolidine-1,2-dicarboxylate

Conditions
ConditionsYield
In dichloromethane for 48h;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

Citrulline
372-75-8

Citrulline

Nα-benzyloxy-carbonyl-L-citrulline
6692-89-3

Nα-benzyloxy-carbonyl-L-citrulline

Conditions
ConditionsYield
Stage #1: Citrulline With sodium hydrogencarbonate In water at 20℃; for 1h;
Stage #2: N-(Benzyloxycarbonyloxy)succinimide In 1,2-dimethoxyethane; water at 20℃;		100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

β-D-galactopyranosyl-(1→4)-2-(t-butyloxycarbonylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-2-deoxy-2-trifluoroacetamido-D-glucopyranoside-(1→3)-β-D-galactopyranosyl-(1→4)-2-amino-2-deoxy-α,β-D-glucopyranoside

β-D-galactopyranosyl-(1→4)-2-(t-butyloxycarbonylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-2-deoxy-2-trifluoroacetamido-D-glucopyranoside-(1→3)-β-D-galactopyranosyl-(1→4)-2-amino-2-deoxy-α,β-D-glucopyranoside

β-D-galactopyranosyl-(1→4)-2-deoxy-2-(t-butyloxycarbonylamino)-β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-2-deoxy-2-trifluoroacetamido-D-glucopyranoside-(1→3)-β-D-galactopyranosyl-(1→4)-2-(benzyloxycarbonylamino)-2-deoxy-α,β-D-glucopyranoside

β-D-galactopyranosyl-(1→4)-2-deoxy-2-(t-butyloxycarbonylamino)-β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-2-deoxy-2-trifluoroacetamido-D-glucopyranoside-(1→3)-β-D-galactopyranosyl-(1→4)-2-(benzyloxycarbonylamino)-2-deoxy-α,β-D-glucopyranoside

Conditions
ConditionsYield
With sodium hydrogencarbonate In water at 37℃; for 1h; Inert atmosphere;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

(2S)-2-amino-3-(2-nitrophenyl)propanoic acid
1991-82-8, 35378-63-3, 19883-75-1

(2S)-2-amino-3-(2-nitrophenyl)propanoic acid

(S)-2-(((benzyloxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid

(S)-2-(((benzyloxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile at 20℃;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

4-nitro-3-phenyl-L-alanine
949-99-5

4-nitro-3-phenyl-L-alanine

(S)-2-(((benzyloxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid
17224-90-7

(S)-2-(((benzyloxy)carbonyl)amino)-3-(4-nitrophenyl)propanoic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile at 20℃;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

(2S)-2-amino-3-(3-nitrophenyl)propanoic acid
19883-74-0

(2S)-2-amino-3-(3-nitrophenyl)propanoic acid

(S)-2-(((benzyloxy)carbonyl)amino)-3-(3-nitrophenyl)propanoic acid

(S)-2-(((benzyloxy)carbonyl)amino)-3-(3-nitrophenyl)propanoic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; acetonitrile at 20℃;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

C14H17NO2

C14H17NO2

C22H23NO4

C22H23NO4

Conditions
ConditionsYield
With sodium hydrogencarbonate at 20℃;100%
With sodium hydrogencarbonate at 20℃;100%
With sodium hydrogencarbonate at 20℃;100%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

rac-((RS)-1-amino-3-phenylpropyl)phosphinic acid

rac-((RS)-1-amino-3-phenylpropyl)phosphinic acid

(1-(((benzyloxy)carbonyl)amino)-3-phenylpropyl)phosphinic acid
234452-57-4

(1-(((benzyloxy)carbonyl)amino)-3-phenylpropyl)phosphinic acid

Conditions
ConditionsYield
With sodium carbonate In tetrahydrofuran; water at 0 - 20℃; for 24.25h; Inert atmosphere;100%

N-(Benzyloxycarbonyloxy)succinimide Specification

The N-(Benzyloxycarbonyloxy)succinimide, with the cas registry number 13139-17-8, has the systematic name of 1-{[(benzyloxy)carbonyl]oxy}pyrrolidine-2,5-dione and the IUPAC name of benzyl (2,5-dioxopyrrolidin-1-yl) carbonate. This chemical is a kind of white crystal powde and it is sensitive.

The followings are the basic information of this chemical: Its product categories are various, including peptide coupling agents; amino acid derivatives; medical intermediates; imidazoles, pyrroles, pyrazoles, pyrrolidines; n-protecting reagents; biochemistry; condensation & active esterification; n-substituted maleimides, succinimides & phthalimides; n-substituted succinimides; peptide synthesis. As to its usage, it is usually used to be polypeptide reagent.

The characteristics of this chemical are as follows: (1)ACD/LogP: 0.42; (2)ACD/LogD (pH 5.5): 0.42; (3)ACD/LogD (pH 7.4): 0.42; (4)ACD/BCF (pH 5.5): 1.23; (5)ACD/BCF (pH 7.4): 1.23; (6)ACD/KOC (pH 5.5): 40.42; (7)ACD/KOC (pH 7.4): 40.42; (8)#H bond acceptors: 6; (9)#Freely Rotating Bonds: 5; (10)Polar Surface Area: 72.91; (11)Index of Refraction: 1.583; (12)Molar Refractivity: 60.2 cm3; (13)Molar Volume: 180 cm3; (14)Polarizability: 23.86 ×10-24 cm3; (15)Surface Tension: 58 dyne/cm; (16)Density: 1.38 g/cm3; (17)Flash Point: 177 °C; (18)Enthalpy of Vaporization: 61.57 kJ/mol; (19)Boiling Point: 369 °C at 760 mmHg; (20)Vapour Pressure: 1.23E-05 mmHg at 25°C; (21)Exact Mass: 249.063722; (22)MonoIsotopic Mass: 249.063722; (23)Topological Polar Surface Area: 72.9; (24)Heavy Atom Count: 18; (25)Complexity: 332.

The production method is as below: carbonochloridic acid benzyl ester could react with dicyclohexylamine salt of N-hydroxysuccinimide to produce N-(Benzyloxycarbonyloxy)succinimide, with the following condition: solution: CHCl3; yield: 90%.

Use of N-(Benzyloxycarbonyloxy)succinimide is as below: N-(Benzyloxycarbonyloxy)succinimide could react with L-serine to produce N-benzyloxycarbonyl-L-serine, with the following condition: reagent:sodium bicarbonate; solution: H2O and acetone; yield: 92% .

When dealing with this chemical, you should be cautious and then take some measures to protect yourself. Being irritant to eyes, respiratory system and skin, it may cause inflammation to the skin or other mucous membranes, and it may cause sensitisation by skin contact. If by inhalation, in contact with skin or if swallowed, it will be very harmful. Therefore, you should take the following instructions. Wear suitable protective clothing and avoid contacting with skin and eyes. If in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice. Then remember not to breathe dust while using .

Additionally, the following data information could be converted into the molecular structure:
(1)SMILES:O=C2N(OC(=O)OCc1ccccc1)C(=O)CC2
(2)InChI:InChI=1/C12H11NO5/c14-10-6-7-11(15)13(10)18-12(16)17-8-9-4-2-1-3-5-9/h1-5H,6-8H2

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