Product Name

  • Name

    Nafoxidine

  • EINECS
  • CAS No. 1847-63-8
  • Article Data6
  • CAS DataBase
  • Density 1.137g/cm3
  • Solubility
  • Melting Point 165-168℃
  • Formula C29H31 N O2 . Cl H
  • Boiling Point 574.5°Cat760mmHg
  • Molecular Weight 462.032
  • Flash Point 176.7°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes 20/21/22-40
  • Molecular Structure Molecular Structure of 1847-63-8 (Nafoxidine)
  • Hazard Symbols Xn
  • Synonyms Pyrrolidine,1-[2-[4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]ethyl]-,hydrochloride (9CI); Pyrrolidine,1-[2-[p-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy]ethyl]-,hydrochloride (7CI,8CI);1-[2-[p-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy]ethyl]pyrrolidinehydrochloride; 11100A; NSC 70735; Nafoxidine hydrochloride; U 11100; U 11100A
  • PSA 21.70000
  • LogP 6.81500

NAFOXIDINE HYDROCHLORIDE Toxicity Data With Reference

1.   

spm-rbt-scu 45 mg/kg

    JRPFA4    Journal of Reproduction and Fertility. 11 (1966),107.
2.   

spm-rbt-unr 45 mg/kg/45D-I

    ADRPBI    Advances in Reproductive Physiology. 4 (1969),65.
3.   

orl-rbt TDLo:12,300 µg/kg (female 6-8D post):TER

    FESTAS    Fertility and Sterility. 16 (1965),281.
4.   

orl-rat LD50:302 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 112 (1963),439.
5.   

ipr-mus LD50:143 mg/kg

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 112 (1963),439.

NAFOXIDINE HYDROCHLORIDE Consensus Reports

EPA Genetic Toxicology Program.

NAFOXIDINE HYDROCHLORIDE Safety Profile

Poison by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.
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