PF 03716556 supplier | CasNO.928774-43-0

Name
PF03716556
EINECS
CAS No. 928774-43-0
Density 1.306 g/cm³
Solubility
Melting Point 143-145 °C
Formula C₂₂H₂₆N₄O₃
Boiling Point
Molecular Weight 394.47
Flash Point
Transport Information
Appearance Light Tan Solid
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms N-(2-Hydroxyethyl)-N,2-dimethyl-8-[[(4R)-5-methylchroman-4-yl]amino]imidazo[1,2-a]pyridine-6-carboxamide;8-[[(4R)-3,4-Dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethyl-imidazo[1,2-a]pyridine-6-carboxamide;Imidazo[1,2-a]pyridine-6-carboxamide, 8-[[(4R)-3,4-dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethyl-;
PSA 79.10000
LogP 3.02410

PF 03716556 Specification

The PF 03716556, with the CAS registry number 928774-43-0, is also known as Imidazo[1,2-a]pyridine-6-carboxamide, 8-[[(4R)-3,4-dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethyl-. It belongs to the product categories of Amines; Aromatics; Heterocycles; Inhibitors; Intermediates & Fine Chemicals; Pfizer Compounds; Pharmaceuticals. This chemical's molecular formula is C₂₂H₂₆N₄O₃ and molecular weight is 394.47. What's more, its systematic name is N-(2-hydroxyethyl)-N,2-dimethyl-8-[[(4R)-5-methylchroman-4-yl]amino]imidazo[1,2-a]pyridine-6-carboxamide. It is used as a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease.

Physical properties of PF 03716556 are: (1)ACD/LogP: 1.83; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.322; (4)ACD/LogD (pH 7.4): 1.821; (5)ACD/BCF (pH 5.5): 4.488; (6)ACD/BCF (pH 7.4): 14.159; (7)ACD/KOC (pH 5.5): 72.954; (8)ACD/KOC (pH 7.4): 230.177; (9)#H bond acceptors: 7; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 79.1 Å²; (13)Index of Refraction: 1.651; (14)Molar Refractivity: 110.299 cm³; (15)Molar Volume: 301.95 cm³; (16)Polarizability: 43.726×10^-24cm³; (17)Surface Tension: 49.352 dyne/cm; (18)Density: 1.306 g/cm³.

You can still convert the following datas into molecular structure:
(1)SMILES: Cc1cccc2c1[C@@H](CCO2)Nc3cc(cn4c3nc(c4)C)C(=O)N(C)CCO
(2)Std. InChI: InChI=1S/C22H26N4O3/c1-14-5-4-6-19-20(14)17(7-10-29-19)24-18-11-16(22(28)25(3)8-9-27)13-26-12-15(2)23-21(18)26/h4-6,11-13,17,24,27H,7-10H2,1-3H3/t17-/m1/s1
(3)Std. InChIKey: YBHKBMJREUZHOV-QGZVFWFLSA-N

Product Name

PF03716556

PF 03716556 Specification

Related Products

Hot Products