Product Name

  • Name

    Cytochalasin H

  • EINECS
  • CAS No. 53760-19-3
  • Article Data4
  • CAS DataBase
  • Density 1.19g/cm3
  • Solubility
  • Melting Point 252-258 °C
  • Formula C30H39 N O5
  • Boiling Point 676.5°Cat760mmHg
  • Molecular Weight 493.643
  • Flash Point 362.9°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes R26/27/28; R63
  • Molecular Structure Molecular Structure of 53760-19-3 (Cytochalasin H)
  • Hazard Symbols T+
  • Synonyms [11]Cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-,(7S,13E,16S,18R,19E,21R)-; 1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,[3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-; Cytochalasin H;Cytochalasin O; Kodocytochalasin 1; Paspalin P I
  • PSA 95.86000
  • LogP 4.06690

Paspalin Chemical Properties

Product Name: Paspalin
Synonyms of Paspalin (CAS NO.53760-19-3) : (11)Cytochalasa-6(12),13,19-trien-1-one, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18S,19E,21R)- ; 21-Acetoxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl-(11)cytochalasa-6(12),13,19-triene-1-one ; Cytochalasin-H ; Paspalin
InChI:InChI=1/C30H39NO5/c1-18-10-9-13-23-27(33)20(3)19(2)26-24(16-22-11-7-6-8-12-22)31-28(34)30(23,26)25(36-21(4)32)14-15-29(5,35)17-18/h6-9,11-15,18-19,23-27,33,35H,3,10,16-17H2,1-2,4-5H3,(H,31,34)/b13-9+,15-14+/t18-,19+,23-,24-,25+,26-,27+,29+,30?/m0/s1
Product Categories: Enzyme Inhibitors;Enzyme Inhibitors by Type;Other;Actin Inhibitors and ProbesCell Signaling and Neuroscience;Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Mold;Toxins and Venoms
CAS NO: 53760-19-3
Molecular Formula:C30H39NO5
Molecular Weight :493.63
Molecular Structure :
Index of Refraction:1.591
Surface Tension: 51.7 dyne/cm
Density: 1.19 g/cm3
Flash Point: 362.9 °C
Enthalpy of Vaporization: 104.33 kJ/mol
Boiling Point: 676.5 °C at 760 mmHg
Vapour Pressure: 3.17E-19 mmHg at 25°C
Melting Point: 252-258 °C
Storage temp: 2-8°C
Solubility : chloroform: 10 mg/mL, Paspalin (CAS NO.53760-19-3) is clear, colorless.

Paspalin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 oral 12500ug/kg (12.5mg/kg)   Canadian Journal of Microbiology. Vol. 22, Pg. 1137, 1976.
mammal (species unspecified) LD50 intraperitoneal 2341ug/kg (2.341mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ATAXIA		 Indian Drugs. Vol. 15, Pg. 76, 1978.
mouse LD50 intravenous 2mg/kg (2mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 2, Pg. 439, 1980.
mouse LDLo unreported 2mg/kg (2mg/kg)   Japanese Journal of Experimental Medicine. Vol. 48, Pg. 105, 1978.

Paspalin Safety Profile

Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Hazard Codes VeryT+
Risk Statements 26/27/28-63
R26/27/28: Paspalin (CAS NO.53760-19-3) is very toxic by inhalation, in contact with skin and if swallowed. 
R63:Possible risk of harm to the unborn child.
Safety Statements 28-36/37-45
S28:After contact with skin, wash immediately with plenty of soap-suds. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR UN 3462 6.1/PG 2
WGK Germany 3
RTECS HA5306000
F 10
HazardClass 6.1(a)
PackingGroup I

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