Product Name

  • Name

    Pazufloxacin

  • EINECS 635-036-1
  • CAS No. 127045-41-4
  • Article Data2
  • CAS DataBase
  • Density 1.56 g/cm3
  • Solubility
  • Melting Point 269-271 °C
  • Formula C16H15FN2O4
  • Boiling Point 531.5 °C at 760 mmHg
  • Molecular Weight 318.305
  • Flash Point 275.2 °C
  • Transport Information
  • Appearance like white to light yellow crystalline
  • Safety 36/37
  • Risk Codes 20/21/22
  • Molecular Structure Molecular Structure of 127045-41-4 (Pazufloxacin)
  • Hazard Symbols HarmfulXn,CorrosiveC,FlammableF
  • Synonyms Pasil;Pasil (TN);PZFX;7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-, (S)-;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6- carboxylic acid,10-(1-aminocyclopropyl)-9- fluoro-2,3-dihydro-3-methyl-7-oxo-,(3S)-;T 3761;(-)-(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)-;T-3761;Pazufloxacin Mesylas;Pazufloxaxin;(S)-10-(1-aminocyclopropyl)-9-fluoro-3-methy...;
  • PSA 94.55000
  • LogP 2.44030

Pazufloxacin Chemical Properties

Systematic Name: (3S)-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
Synonyms of Pazufloxacin (CAS NO.127045-41-4): (-)-(3S)-10-(1-Aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid ; 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 10-(1-aminocyclopropyl)-9-fluoro-2,3-dihydro-3-methyl-7-oxo-, (S)- ; H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-, (S)-
Product Categories: BacteriostaticAntibiotics;ChinolonesAlphabetic;PA - PENAnalytical Standards;Pharmacology Standards;Antibiotics;Chemical Structure;Chromatography;P;Principle;API's
CAS NO:127045-41-4
Molecular Formula: C16H15FN2O4
Molecular Weight: 318.3
Molecular Structure:
Index of Refraction: 1.692
Surface Tension: 76.4 dyne/cm
Density: 1.56 g/cm3
Flash Point: 275.2 °C
Enthalpy of Vaporization: 84.94 kJ/mol
Boiling Point: 531.5 °C at 760 mmHg
Vapour Pressure: 4E-12 mmHg at 25°C
Melting Point: 269-271°C

Pazufloxacin Uses

 Pazufloxacin (CAS NO.127045-41-4) is used for the treatment of acute and chronic pneumonia, respiratory infections and other illnesses.

Pazufloxacin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 2gm/kg (2000mg/kg)   Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
dog LDLo intravenous 400mg/kg (400mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING		 Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
mouse LD oral > 5gm/kg (5000mg/kg)   Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
mouse LD subcutaneous > 5gm/kg (5000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
mouse LD50 intravenous 783mg/kg (783mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
rat LD oral > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 43(Suppl,
rat LD subcutaneous > 5gm/kg (5000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.
rat LD50 intravenous 341mg/kg (341mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Japanese Journal of Antibiotics. Vol. 48, Pg. 754, 1995.

Pazufloxacin Safety Profile

Hazard Codes: HarmfulXn,CorrosiveC,FlammableF
Risk Statements: 20/21/22-34-11
R11: Pazufloxacin (CAS NO.127045-41-4)  is highly flammable. 
R34: Causes burns. 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 45-36/37/39-26-16
S16: Keep Pazufloxacin (CAS NO.127045-41-4) away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RTECS: UU8815300

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