-
Name
2-{4-[3-(1-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol hydrochloride (1:1)
- EINECS
- CAS No. 3111-71-5
- Density
- Solubility
- Melting Point
- Formula C21H26 Cl N3 O S . Cl H
- Boiling Point 578.4°C at 760 mmHg
- Molecular Weight 440.47
- Flash Point 303.6°C
- Transport Information
- Appearance
- Safety Poison by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl−, NOx, SOx and HCl.
- Risk Codes
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Molecular Structure
- Hazard Symbols
- Synonyms 1-Piperazineethanol,4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-, monohydrochloride (9CI);1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-,monohydrochloride (8CI)
- PSA
- LogP
Perphenazine hydrochloride Chemical Properties
IUPAC Name: 2-[4-[3-(1-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol hydrochloride
Synonyms of Perphenazine hydrochloride (CAS NO.3111-71-5) : Perphenazine HCl ; Perphenazine hydrochloride ; 1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-, monohydrochloride
CAS NO: 3111-71-5
Molecular Formula:C21H27Cl2N3OS
Molecular Weight :440.4296
Molecular Structure :.png)
Flash Point: 303.6 °C
Enthalpy of Vaporization: 91.06 kJ/mol
Boiling Point: 578.4 °C at 760 mmHg
Vapour Pressure: 3.2E-14 mmHg at 25°C
Perphenazine hydrochloride Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 287800ug/kg (287.8mg/kg) | Drugs in Japan Vol. -, Pg. 1266, 1995. | |
| mouse | LD50 | intravenous | 46mg/kg (46mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Collection of Czechoslovak Chemical Communications. Vol. 38, Pg. 2137, 1973. |
| mouse | LD50 | oral | 287mg/kg (287mg/kg) | Drugs in Japan Vol. -, Pg. 1266, 1995. | |
| rat | LD50 | intraperitoneal | 138100ug/kg (138.1mg/kg) | Drugs in Japan Vol. -, Pg. 1266, 1995. | |
| rat | LD50 | oral | 210mg/kg (210mg/kg) | Drugs in Japan Vol. -, Pg. 1266, 1995. |
Perphenazine hydrochloride Safety Profile
Perphenazine hydrochloride (CAS NO.3111-71-5) is poisonous by intravenous route. An experimental teratogen. Experimental reproductive effects. When Perphenazine hydrochloride (CAS NO.3111-71-5) is heated to decomposition, it emits very toxic fumes of Cl−, NOx, SOx and HCl.
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