Product Name: Platyphylline
Synonyms: 1alpha,13S,15Z)-12-Hydroxy-1,2-dihydrosenecionan-11,16-dione ; [1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidenedodecahydro-6-hydroxy-5,6-dimethyl-, (3Z,5S,6R,9aS,14aR,14bR)-
CAS NO: 480-78-4
Molecular Formula of Platiphillin (CAS NO.480-78-4) : C18H27NO5
Molecular Weight of Platiphillin (CAS NO.480-78-4) : 337.4107
Molecular Structure of Platiphillin (CAS NO.480-78-4) :
EINECS: 207-558-6
Index of Refraction: 1.553
Surface Tension: 49.6 dyne/cm
Density: 1.22 g/cm3
Flash Point: 280.1 °C
Enthalpy of Vaporization: 93.95 kJ/mol
Boiling Point: 539.6 °C at 760 mmHg
Vapour Pressure: 6.81E-14 mmHg at 25°
Platifillin has holinoliticheskoe effect.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 577mg/kg (577mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997. |
mouse | LD50 | intravenous | 105mg/kg (105mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE" | Research Today. Vol. 5, Pg. 53, 1949. |
mouse | LD50 | oral | 2573mg/kg (2573mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997. |
rat | LD50 | intraperitoneal | 252mg/kg (252mg/kg) | Australian Journal of Experimental Biology and Medical Science. Vol. 46, Pg. 493, 1968. | |
rat | LD50 | intravenous | 60mg/kg (60mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" BLOOD: "LYMPHOMA, INCLUDING HODGKIN'S DISEASE" | Research Today. Vol. 5, Pg. 53, 1949. |
rat | LD50 | oral | 3100mg/kg (3100mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Toksikologicheskii Vestnik. Vol. (1), Pg. 34, 1997. |
A poison by intraperitoneal and intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.
RIDADR 1544
HazardClass 6.1(b)
PackingGroup III
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