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Name
PROCHLORPERAZINE MALEATE
- EINECS 201-511-3
- CAS No. 84-02-6
- Density
- Solubility Soluble to 25 mM in DMSO,Very slightly sol in water (<0.1% at 20°). Slightly sol in methanol, ethanol. Practically insol in ether
- Melting Point 228ºC
- Formula C20H24ClN3S•2C4H4O4
- Boiling Point 524.8 °C at 760 mmHg
- Molecular Weight 606.096
- Flash Point 271.2 °C
- Transport Information
- Appearance Off-White Powder
- Safety 36
- Risk Codes 20/21/22
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Molecular Structure
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Hazard Symbols
Xn
- Synonyms PROCHLORPERAZINE DIMALEATE;PROCHLORPERAZINE DIMALEATE SALT;PROCHLORPERAZINE MALEATE;2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine,dimaleate;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10h-phenothiazin(z)-2-but;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinedimaleate;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1:2);buccastem
- PSA 184.22000
- LogP 3.94460
Prochlorperazine hydrogen maleate Chemical Properties
IUPAC Name: (Z)-But-2-enedioic acid; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
Synonyms: 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, (2Z)-2-butenedioate (1:2) ; 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine (2Z)-but-2-enedioate (1:2) ; 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine di[(2Z)-but-2-enedioate] ; Acide (2Z)-but-2-ènedioïque-2-chloro-10-[3-(4-méthylpipérazin-1-yl)propyl]-10H-phénothiazine (2:1)
Product Categories: Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Antagonists;Dopaminergics;Neurotransmitters
CAS NO: 84-02-6
Molecular Formula of Prochlorperazine hydrogen maleate (CAS NO.84-02-6) : C28H32ClN3O8S
Molecular Weight of Prochlorperazine hydrogen maleate (CAS NO.84-02-6) : 606.09
Molecular Structure of Prochlorperazine hydrogen maleate (CAS NO.84-02-6) :
EINECS: 201-511-3 
Flash Point: 271.2 °C
Enthalpy of Vaporization: 79.88 kJ/mol
Boiling Point: 524.8 °C at 760 mmHg
Vapour Pressure: 4.15E-11 mmHg at 25°C
Appearance:Off-White Powder
Prochlorperazine hydrogen maleate Uses
Prochlorperazine hydrogen maleate (CAS NO.84-02-6) has significant sedative effect, for acute and chronic mental illness, neurosis, and antiemetic.And can also be used for Meniere's syndrome.
Prochlorperazine hydrogen maleate Toxicity Data With Reference
| 1. | orl-rat LD50:750 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 123 (1959),78. | ||
| 2. | scu-mus LD50:320 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,40. | ||
| 3. | ivn-mus LD50:142 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 123 (1959),78. |
Prochlorperazine hydrogen maleate Safety Profile
Poison by ingestion, intravenous, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of Cl−, NOx, and SOx.
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