Product Name

  • Name

    fluphenazine O-enantate

  • EINECS
  • CAS No. 2746-81-8
  • Density 1.181g/cm3
  • Solubility
  • Melting Point 184.5°C
  • Formula C29H38 F3 N3 O2 S
  • Boiling Point 629.4°Cat760mmHg
  • Molecular Weight 549.701
  • Flash Point 334.4°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous, intramuscular, intraperitoneal, and subcutaneous routes. Human systemic effects by subcutaneous route: muscle weakness; by intramuscular route: musculo-skeletal changes. When heated to decomposition it emits very toxic fumes of F, SOx, and NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 2746-81-8 (fluphenazine O-enantate)
  • Hazard Symbols
  • Synonyms Heptanoicacid, 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethylester (7CI,8CI); 1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-, heptanoate (ester) (8CI);4-[3-(2-Trifluoromethyl-10-phenothiazinyl)propyl]-1-piperazineethanolenanthate; Fluphenazine enanthate; Moditen enanthate; Prolixin enanthate; SQ16,114; SQ 16144
  • PSA 61.32000
  • LogP 6.77020

Prolixin enanthate Chemical Properties

IUPAC Name: 2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl heptanoate
Synonyms of Prolixin enanthate (CAS NO.2746-81-8): 2-(4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazinyl)ethyl heptanoate ; 4-(3-(2-Trifluoromethyl-10-phenothiazinyl)propyl)-1-piperazineethanol enanthate ; Eutimox ; Fluphenazine enantate ; Heptanoic acid, 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazinyl)ethyl ester
CAS NO: 2746-81-8
Molecular Formula: C29H38F3N3O2S
Molecular Weight : 549.6911
Molecular Structure:
EINECS: 220-385-0
H bond acceptors: 5
H bond donors: 0
Freely Rotating Bonds: 13
Polar Surface Area: 61.32 Å2
Index of Refraction: 1.544
Molar Refractivity: 146.97 cm3
Molar Volume: 465.4 cm3
Surface Tension: 40.6 dyne/cm
Density: 1.181 g/cm3
Flash Point: 334.4 °C
Enthalpy of Vaporization: 93.11 kJ/mol
Boiling Point: 629.4 °C at 760 mmHg
Vapour Pressure: 9.41E-16 mmHg at 25°C 

Prolixin enanthate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo intramuscular 1633ug/kg (1.633mg/kg) MUSCULOSKELETAL: OTHER CHANGES British Medical Journal. Vol. 2, Pg. 1071, 1966.
human TDLo subcutaneous 357ug/kg (0.357mg/kg) BEHAVIORAL: MUSCLE WEAKNESS American Journal of Psychiatry. Vol. 119, Pg. 779, 1963.
mouse LD50 intramuscular 17200ug/kg (17.2mg/kg)   Drugs in Japan Vol. 6, Pg. 701, 1982.
mouse LD50 intraperitoneal 300mg/kg (300mg/kg)   Drugs in Japan Vol. 6, Pg. 701, 1982.
mouse LD50 intravenous 56mg/kg (56mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03337,
mouse LD50 oral 41300ug/kg (41.3mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1421, 1969.
mouse LD50 subcutaneous 50mg/kg (50mg/kg)   Drugs in Japan Vol. 6, Pg. 701, 1982.
rat LD50 intraperitoneal 230mg/kg (230mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1421, 1969.
rat LD50 oral 230mg/kg (230mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1421, 1969.
rat LD50 subcutaneous 475mg/kg (475mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1421, 1969.
women TDLo intramuscular 250ug/kg (0.25mg/kg) BRAIN AND COVERINGS: CHANGES IN SURFACE EEG

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: COMA
Italian Journal of Neurological Sciences. Vol. 1, Pg. 193, 1980.

Prolixin enanthate Safety Profile

Poison by intravenous, intramuscular, intraperitoneal, and subcutaneous routes. Human systemic effects by subcutaneous route: muscle weakness; by intramuscular route: musculo-skeletal changes. When Prolixin enanthate (CAS NO.2746-81-8) is heated to decomposition, it emits very toxic fumes of F, SOx, and NOx.

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

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