Lactamide

The Propanamide, 2-hydroxy-, with the CAS registry number 2043-43-8, is also known as Lactamide. Its EINECS registry number is 218-049-3. This chemical's molecular formula is C₃H₇NO₂ and molecular weight is 89.09. What's more, both its IUPAC name and systematic name are the same which is called 2-Hydroxypropanamide.

Physical properties about Propanamide, 2-hydroxy- are: (1) ACD/LogP: -1.68; (2) # of Rule of 5 Violations: 0; (3) ACD/LogD (pH 5.5): -1.68; (4) ACD/LogD (pH 7.4): -1.68; (5) ACD/BCF (pH 5.5): 1; (6) ACD/BCF (pH 7.4): 1; (7) ACD/KOC (pH 5.5): 2.9; (8) ACD/KOC (pH 7.4): 2.9; (9) #H bond acceptors: 3; (10) #H bond donors: 3; (11) #Freely Rotating Bonds: 2; (12) Polar Surface Area: 29.54 Å²; (13) Index of Refraction: 1.459; (14) Molar Refractivity: 21 cm³; (15) Molar Volume: 76.7 cm³; (16) Surface Tension: 45.8 dyne/cm; (17) Density: 1.161 g/cm³; (18) Flash Point: 124.3 °C; (19) Enthalpy of Vaporization: 60.44 kJ/mol; (20) Boiling Point: 281.9 °C at 760 mmHg; (21) Vapour Pressure: 0.000409 mmHg at 25 °C; (22) Melting Point: 73-76 °C.

Preparation of Propanamide, 2-hydroxy-: this chemical can be prepared by 2-Hydroxy-propionitrile. This reaction needs reagent HCl and solvent Propan-2-ol.



Uses of Propanamide, 2-hydroxy-: it is used to produce other chemicals. For example, it is used to produce Pyruvamide. The reaction occurs with reagent Sodium dichromate, Sulphuric acid and solvent H₂O, Acetone at temperature of 20 °C for 30 minutes. The yield is 51 %.

When you are dealing with this chemical, you should be very careful. The gas of this chemical can not be breathed. You should avoid contacting with skin and eyes.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(N)C(O)C
(2) InChI: InChI=1/C3H7NO2/c1-2(5)3(4)6/h2,5H,1H3,(H2,4,6)
(3) InChIKey: SXQFCVDSOLSHOQ-UHFFFAOYAP