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    2-(7-methoxy-10-methyl-phenothiazin-2-yl)propanoic acid

  • EINECS
  • CAS No. 54323-85-2
  • Density
  • Solubility
  • Melting Point
  • Formula
  • Boiling Point
  • Molecular Weight 0
  • Flash Point
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  • Risk Codes
  • Molecular Structure Molecular Structure of 54323-85-2 (2-(7-methoxy-10-methyl-phenothiazin-2-yl)propanoic acid)
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  • Synonyms 2-(7-methoxy-10-methyl-phenothiazin-2-yl)propanoic acid
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Protizinic acid Chemical Properties

IUPAC Name: 2-(7-Methoxy-10-methylphenothiazin-2-yl)propanoic acid
The molecular formula of Protizinic acid (CAS NO.54323-85-2) is C17H17NO3S.

                     
The molecular weight of Protizinic acid (CAS NO.54323-85-2) is 315.3868.
Synonyms of Protizinic acid (CAS NO.54323-85-2): 10H-Phenothiazine-2-acetic acid, 7-methoxy-alpha,10-dimethyl- ; 2-(7-Methoxy-10-methyl-10H-phenothiazin-2-yl)propanoic acid
Index of Refraction: 1.636 
Density: 1.285 g/ml 
Flash Point: 271.1 °C 
Boiling Point: 524.6 °C

Protizinic acid Uses

 Protizinic acid (CAS NO.54323-85-2) is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.

Protizinic acid Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 400mg/kg (400mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 181, 1980.
mouse LD50 intravenous 232mg/kg (232mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 408, 1975.
mouse LD50 oral 1250mg/kg (1250mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 181, 1980.
mouse LD50 subcutaneous 470mg/kg (470mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ATAXIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 60, 1975.
rat LD50 intraperitoneal 350mg/kg (350mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 181, 1980.
rat LD50 intravenous 326mg/kg (326mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ATAXIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 60, 1975.
rat LD50 oral 738mg/kg (738mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ATAXIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 60, 1975.
rat LD50 subcutaneous 375mg/kg (375mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ATAXIA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 60, 1975.

Protizinic acid Safety Profile

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx. An anti-inflammatory agent.

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