2-CHLORO-6-ETHOXYPYRIDINE

The Pyridine,2-chloro-6-ethoxy-, with the CAS registry number 42144-78-5, is also known as NSC148330. It belongs to the product categories of Chloropyridines; Halopyridines. Its EINECS number is 255-681-9. This chemical's molecular formula is C₇H₈ClNO and molecular weight is 157.6. Its IUPAC name is called 2-chloro-6-ethoxypyridine. This chemical should be stored in dry and cool place.

Physical properties of Pyridine,2-chloro-6-ethoxy-: (1)ACD/LogP: 2.76; (2)ACD/LogD (pH 5.5): 2.76; (3)ACD/LogD (pH 7.4): 2.76; (4)ACD/BCF (pH 5.5): 73.47; (5)ACD/BCF (pH 7.4): 73.47; (6)ACD/KOC (pH 5.5): 753.99; (7)ACD/KOC (pH 7.4): 753.99; (8)#H bond acceptors: 2; (9)#Freely Rotating Bonds: 2; (10)Index of Refraction: 1.512; (11)Molar Refractivity: 40.55 cm³; (12)Molar Volume: 135.1 cm³; (13)Surface Tension: 37.2 dyne/cm; (14)Density: 1.166 g/cm³; (15)Flash Point: 79.6 °C; (16)Enthalpy of Vaporization: 42.61 kJ/mol; (17)Boiling Point: 207.9 °C at 760 mmHg; (18)Vapour Pressure: 0.316 mmHg at 25°C.

Preparation: this chemical can be prepared by ethanol; sodium salt and 2-chloro-6-methylsulfonylpyridine. This reaction will need solvent ethanol. The reaction time is 1 hour with reaction temperature of 50 °C. The yield is about 84%.

Uses of Pyridine,2-chloro-6-ethoxy-: it can be used to produce 2,6-dichloro-pyridine at temperature of 105 °C. This reaction will need reagent POCl₃, DMF with reaction time of 18 hours. The yield is about 46%.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. You should not breathe its dust. Whenever you will contact it, please wear suitable protective clothing and gloves.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CCOC1=NC(=CC=C1)Cl
(2)InChI: InChI=1S/C7H8ClNO/c1-2-10-7-5-3-4-6(8)9-7/h3-5H,2H2,1H3
(3)InChIKey: AMSLPXHLKHZWBJ-UHFFFAOYSA-N