Product Name

  • Name

    QUINIDINE SULFATE

  • EINECS 200-046-3
  • CAS No. 50-54-4
  • Density g/cm3
  • Solubility
  • Melting Point 212°C
  • Formula C40H48N4O4•H2O4S
  • Boiling Point 495.9°Cat760mmHg
  • Molecular Weight 746.925
  • Flash Point 253.7°C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also QUINIDINE.
  • Risk Codes 22
  • Molecular Structure Molecular Structure of 50-54-4 (QUINIDINE SULFATE)
  • Hazard Symbols Xn
  • Synonyms Quinidine bisulfate;Quinidine, sulfate (2:1) (salt);Quinitex;Cinchonan-9-ol,6'-methoxy-,(9S)-,sulfate (2:1) (salt);Auriquin;Quinidex;Quinidine sulfate anhydrous;Cin-Quin;Vanquin;Quinidate;QUINIDINE;Kinichron;(S)-[(4S,5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Cinchonan-9-ol, 6-methoxy-, (9S)-, sulfate (2:1) (salt);Quinidine monosulfate;Quinidine sulfate (salt);Cin quin;Quinora;Chinidine sulfate;Quinicardine;Quinidine sulfate;SK-Quinidine sulfate;Systodin;(9S)-6′-METHOXYCINCHONAN-9-OL SULFATE (2:1) (SALT);QUINIDINE SULPHATE;CINCHONAN-9-OL, 6′-METHOXY-, (9S)-, SULFATE (2:1) (SALT) (9CI);
  • PSA 174.16000
  • LogP 6.65020

QUINIDINE SULFATE (2:1) (salt) Chemical Properties

MF: C40H50N4O8S
MW: 746.91
EINECS: 200-046-3
Product Categories: Organics
Melting Point Quinidinesulfate(2:1)(salt) (50-54-4):: 212°C
IUPAC Name: (S)-[(5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol ;  sulfuric acid
Synonyms: Quinidinemono sulfate ; (9S)-6’-methoxycinchonan-9-olsulfate(2:1)(salt) ; 6’-Methoxy-cinchonan-9-o(9s)-cinchonan-9-osulfate(2:1)(salt) ; 6’-Methoxycinchonan-9-olsulfate ; Chinidinesulfate ; Quinidate ; Quinidinemonosulfate ; Quinidinesulfate(2:1)(salt)
Following is the molecular structure of Quinidinesulfate(2:1)(salt) (50-54-4):

QUINIDINE SULFATE (2:1) (salt) Toxicity Data With Reference

1.    

orl-man TDLo:240 mg/kg/2W-I:EYE

     JTCTDW    Journal of Toxicology, Clinical Toxicology. 20 (1983),367.
2.    

orl-wmn TDLo:272 mg/kg/17D-I:CVS

     AIMDAP    Archives of Internal Medicine. 145 (1985),2051.
3.    

orl-man TDLo:40 mg/kg/2W-I:CVS

     AIMDAP    Archives of Internal Medicine. 145 (1985),2051.
4.    

orl-hmn TDLo:9600 mg/kg/8W:CNS,PUL

     JAMAAP    JAMA, Journal of the American Medical Association. 238 (1977),884.
5.    

orl-wmn TDLo:409 g/kg/14Y:CNS

     JAMAAP    JAMA, Journal of the American Medical Association. 237 (1977),2093.
6.    

orl-man TDLo:88 mg/kg/10D-I:SYS

     GASTAB    Gastroenterology. 70 (1976),1136.
7.    

orl-wmn TDLo:32 mg/kg/2D:SKN

     DICPBB    Drug Intelligence and Clinical Pharmacy. 16 (1982),615.
8.    

mul-man LDLo:30 mg/kg/2D-I:CVS,PUL

     AIMEAS    Annals of Internal Medicine. 16 (1942),571.
9.    

orl-rat LD50:456 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),1127.
10.    

ipr-rat LDLo:140 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 1 (1959),156.

QUINIDINE SULFATE (2:1) (salt) Consensus Reports

Reported in EPA TSCA Inventory.

QUINIDINE SULFATE (2:1) (salt) Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Safety Information of Quinidinesulfate(2:1)(salt) (50-54-4):
Risk Statements: 22
22: Harmful if swallowed 
Safety Statements: 22-45
22: Do not breathe dust 
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)  
RIDADR: 1544

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