Product Name

  • Name

    Sorafenib tosylate

  • EINECS 641-758-8
  • CAS No. 475207-59-1
  • Density 1.454 g/cm3
  • Solubility
  • Melting Point
  • Formula C21H16ClF3N4O3
  • Boiling Point 523.3 °C at 760 mmHg
  • Molecular Weight 637.03
  • Flash Point 270.3 °C
  • Transport Information
  • Appearance White to off-white crystalline powder
  • Safety 28-26
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 475207-59-1 (Sorafenib tosylate)
  • Hazard Symbols
  • Synonyms Sorafenib tosylate [USAN];1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate);4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N2-methylpyridine-2-carboxamide mono (4-methylbenzenesulfonate);BAY 43-9006;Nexavar(R);UNII-5T62Q3B36J;2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate);
  • PSA 155.10000
  • LogP 8.40910

Sorafenib tosylate Chemical Properties

Molecular structure of Nexavar (CAS NO.475207-59-1) is:

Product Name: Nexavar
CAS Registry Number: 475207-59-1
IUPAC Name: 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide 
Molecular Weight: 464.82495 [g/mol]
Molecular Formula: C21H16ClF3N4O3
XLogP3-AA: 4.1
H-Bond Donor: 3
H-Bond Acceptor: 7 
Surface Tension: 51.7 dyne/cm
Density: 1.454 g/cm3
Flash Point: 270.3 °C
Enthalpy of Vaporization: 79.7 kJ/mol
Boiling Point: 523.3 °C at 760 mmHg
Vapour Pressure: 4.76E-11 mmHg at 25°C

Sorafenib tosylate Uses

 Nexavar (CAS NO.475207-59-1) is commonly used as a potent RAF kinase inhibitor. It is also used as antineoplastic drug.

Sorafenib tosylate Specification

 Nexavar , its cas register number is 475207-59-1. It also can be called Sorafenib tosylate [USAN] ; 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate) ; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N2-methylpyridine-2-carboxamide mono (4-methylbenzenesulfonate) ; BAY 43-9006 ; BAY43-9006 ; Nexavar(R) ; Sorafenib tosylate ; UNII-5T62Q3B36J ; 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate) .

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