Strychnidin-10-one,hydrochloride (1:1) supplier

Name
STRYCHNINE HYDROCHLORIDE
EINECS 215-826-9
CAS No. 1421-86-9
Article Data1
CAS DataBase
Density
Solubility
Melting Point 295 °C
Formula C₂₁H₂₂N₂O₂^.ClH
Boiling Point 578.8 °C at 760 mmHg
Molecular Weight 370.879
Flash Point 303.8 °C
Transport Information UN 1692 6.1/PG 1
Appearance
Safety 22-36/37/39-45-61-60
Risk Codes 26/27/28-51/53
Molecular Structure
Hazard Symbols T+,N
Synonyms Strychnidin-10-one,monohydrochloride (9CI);Strychnine, monohydrochloride (8CI);Strychnine hydrochloride;
PSA 32.78000
LogP 2.89740

Synthetic route

: 57-24-9
strychnidin-10-one

: 1421-86-9
strychnine hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In ethyl acetate

: 592-04-1
mercury(II) cyanide

: 1421-86-9
strychnine hydrochloride

: Strychniniumchlorid * Hg(CN)2

Conditions

Conditions	Yield
In not given in hot dild. soln.; washing with H2O and alcohol, drying at 100°C;

: 592-04-1
mercury(II) cyanide

: 1421-86-9
strychnine hydrochloride

: Strychniniumchlorid * 4Hg(CN)2

Conditions

Conditions	Yield
In water hot soln.; cooling;
In water

: silverdioxalatodimethylethylenediaminechromate(III) * H2O

: 1421-86-9
strychnine hydrochloride

: strychniniumdioxalatodimethylethylenediaminechromate(III)

Conditions

Conditions	Yield
In water heating Ag(Cr(C2O4)2(CH3NHC2H4NHCH3)*H2O with H2O and strychninium chloride on water bath with frequent shaking, until soln. is free ofCl(1-), storing filtered soln. for several days;; pptn.;

: potassiumdioxalatodipyridinechromate(III) * 3 H2O

: 1421-86-9
strychnine hydrochloride

: strychniniumdioxalatodipyridinechromate(III)

Conditions

Conditions	Yield
In water prepn. from aq. solns. of strychninium chloride and K(Cr(C2O4)2(C5H5N)2)*3H2O;;

Strychnidin-10-one,hydrochloride (1:1) Chemical Properties

Strychnine hydrochloride (1421-86-9) is also called for Certox ; Strychnos hydrochloride ; Strychnine HCl ; Strychnidin-10-one,monohydrochloride ; strychnine,monohydrochloride ; Strychnine hydrochloride hydrate and so on.
Molecular Formula: C₂₁H₂₃ClN₂O₂
Molecular Weight: 370.87
EINECS: 215-826-9
Melting Point: 295 °C
Flash Point: 292.4 °C
Boiling Point: 559.9 °C at 760 mmHg
LogP: ACD/LogP: 1.74
ACD/LogD (pH 5.5): -0.95
ACD/LogD (pH 7.4): 0.7
ACD/BCF (pH 5.5): 1
ACD/BCF (pH 7.4): 1.14
ACD/KOC (pH 5.5): 1
ACD/KOC (pH 7.4): 19.31
H bond acceptors: 4
H bond donors: 0
Isotope Atom Count: 0
Defined Atom StereoCenter Count: 0
Undefined Atom StereoCenter Count: 6
Defined Bond StereoCenter Count: 0
Undefined Bond StereoCenter Count: 0
Covalently-Bonded Unit Count: 2
Enthalpy of Vaporization: 84.23 kJ/mol
The molecular structure of Strychnine hydrochloride (1421-86-9):

Strychnidin-10-one,hydrochloride (1:1) Uses

Strychnine hydrochloride (1421-86-9) is used as glycine agents, which mean substances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.

Strychnidin-10-one,hydrochloride (1:1) Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	subcutaneous	460ug/kg (0.46mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Zentralblatt fuer Veterinaermedizin, Reihe A. Vol. 16, Pg. 465, 1969.
mouse	LD50	intravenous	650ug/kg (0.65mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC	Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 12, 1945.
rat	LD50	subcutaneous	2730ug/kg (2.73mg/kg)	BEHAVIORAL: REGIDITY	Zentralblatt fuer Veterinaermedizin, Reihe A.

RTECS: WL2430000

Strychnidin-10-one,hydrochloride (1:1) Safety Profile

Hazard Codes: T+ ,N
Risk Statements: 26/27/28-51/53
R26/27/28: Very Toxic by inhalation, in contact with skin and if swallowed
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements: 22-36/37/39-45-61-60
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
S61: Avoid release to the environment. Refer to special instructions safety data sheet
S60: This material and/or its container must be disposed of as hazardous waste
RIDADR: UN 1692 6.1/PG 1
WGK Germany 3
HazardClass: 6.1(a)
PackingGroup: I

Product Name

STRYCHNINE HYDROCHLORIDE

Synthetic route

Strychnidin-10-one,hydrochloride (1:1) Chemical Properties

Strychnidin-10-one,hydrochloride (1:1) Uses

Strychnidin-10-one,hydrochloride (1:1) Toxicity Data With Reference

Strychnidin-10-one,hydrochloride (1:1) Safety Profile

Related Products

Hot Products