-
Name
SULFAPHENAZOLE
- EINECS
- CAS No. 526-08-9
- Article Data9
- CAS DataBase
- Density 1.39g/cm3
- Solubility
-
Melting Point
179-183 °C
- Formula C15H14 N4 O2 S
- Boiling Point 541.9°Cat760mmHg
- Molecular Weight 314.368
- Flash Point 281.5°C
- Transport Information
- Appearance
- Safety Moderately toxic by subcutaneous and intravenous routes. Mildly toxic by ingestion. See also SULFONATES. When heated to decomposition it emits very toxic fumes of SOx and NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Sulfanilamide,N1-(1-phenylpyrazol-5-yl)- (8CI); 1-Phenyl-5-sulfanilamidopyrazole;2-Phenyl-3-sulfanilamidopyrazole;3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole;5-Sulfanilamido-1-phenylpyrazole; Depocid; Depotsulfonamide; Eftolon;Firmazolo; Inamil; Isarol; Isarol V; Merian; Microtan pirazolo;N1-(1-Phenylpyrazol-5-yl)sulfanilamide; Orisul; Orisulf; Paidazolo; Plisulfan;Raziosulfa; Sulfabid; Sulfaphenazol; Sulfaphenazole; Sulfaphenazon;Sulfaphenylpyrazole; Sulphaphenazole
- PSA 98.39000
- LogP 3.99030
Sulfaphenazole Chemical Properties
IUPAC Name: 4-Amino-N-(2-phenylpyrazol-3-yl)benzenesulfonamide
Synonyms of 3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole (CAS NO: 526-08-9) : 4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide ; Benzenesulfonamide, 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)- ; 1-Phenyl-5-sulfanilamidopyrazole
CAS NO: 526-08-9
Molecular Formula :C15H14N4O2S
Molecular Weight :314.3623
Molecular Structure :
EINECS: 208-384-3
Index of Refraction: 1.684
Surface Tension: 60.9 dyne/cm
Density: 1.39 g/cm3
Flash Point: 281.5 °C
Enthalpy of Vaporization: 81.99 kJ/mol
Boiling Point: 541.9 °C at 760 mmHg
Vapour Pressure: 8.34E-12 mmHg at 25°C
Melting point: 179-183 °C
Storage temp: 2-8°C
Color: 3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole (CAS NO.526-08-9) is white to light yellow.
Sulfaphenazole Uses
3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole (CAS NO.526-08-9) is a sulfonamide antibacterial.
Sulfaphenazole Production
Raw materials :Etanol-->Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Thionyl chloride-->PETROLEUM ETHER-->Triethyl orthoformate-->Ethyl cyanoacetate-->Chlorosulfonic acid-->Sodium dithionite-->Phenylhydrazine-->5-AMINO-1-PHENYLPYRAZOLE-->4-NITROBENZENESULFONIC ACID-->PHENYLURETHANE
Sulfaphenazole Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 470mg/kg (470mg/kg) | Drugs in Japan Vol. 6, Pg. 387, 1982. | |
| mouse | LD50 | oral | 3016mg/kg (3016mg/kg) | Minerva Medica. Vol. 52, Pg. 1789, 1961. | |
| mouse | LD50 | subcutaneous | 660mg/kg (660mg/kg) | Drugs in Japan Vol. 6, Pg. 387, 1982. | |
| rabbit | LD50 | intravenous | 440mg/kg (440mg/kg) | Drugs in Japan Vol. 6, Pg. 387, 1982. | |
| rabbit | LD50 | subcutaneous | 950mg/kg (950mg/kg) | Drugs in Japan Vol. 6, Pg. 387, 1982. | |
| rat | LD50 | intravenous | 525mg/kg (525mg/kg) | Drugs in Japan Vol. 6, Pg. 387, 1982. | |
| rat | LD50 | subcutaneous | 900mg/kg (900mg/kg) | Drugs in Japan Vol. 6, Pg. 387, 1982. |
Sulfaphenazole Safety Profile
Moderately toxic by subcutaneous and intravenous routes. Mildly toxic by ingestion. See also SULFONATES. When heated to decomposition it emits very toxic fumes of SOx and NOx.
WGK Germany 2
RTECS DA9520000
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View