-
Name
Tiquizium bromide
- EINECS 1312995-182-4
- CAS No. 71731-58-3
- Article Data1
- CAS DataBase
- Density
- Solubility
- Melting Point 278-281° (dec)
- Formula C19H24 N S2 . Br
- Boiling Point
- Molecular Weight 410.442
- Flash Point
- Transport Information
- Appearance
- Safety Poison by subcutaneous, intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Br−, NOx, and SOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 2H-Quinolizinium,3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, (5R,9aR)-rel- (9CI);2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide,trans-; HS 902; HSR 902; Thiaton; Tiquizium bromide
- PSA 56.48000
- LogP 2.36720
TIQUIZIUM BROMIDE Chemical Properties
IUPAC Name:(5R,9aR)-7-(dithiophen-2-ylmethylidene)-5-methyl-1,2,3,4,6,8,9,9a-
octahydroquinolizin-5-ium bromide(71731-58-3)
Synonyms: Tiquizium bromide ; (5R,9aR)-7-(dithiophen-2-ylmethylidene)-5-methyl-1,2,3,4,6,8,9,9a-octahydroquinolizin-5-ium bromide ; Tiquizium ; 2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, (5R,9aR)-rel- (9CI) ; 2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, trans- ; HS 902;HSR 902 ; Thiaton
CAS:71731-58-3
MF: C19H24BrNS2
MW: 410.43
Mol File: 71731-58-3.mol
Melting point :246 ~ 248 ℃
Appearance: Tiquizium bromide (71731-58-3) is prism crystals.
TIQUIZIUM BROMIDE Uses
1.Tiquizium bromide (71731-58-3) is antispasmodic, which can be obtained from 2 - hydroxyethyl-pyridine of the raw material;
2.Tiquizium bromide (71731-58-3) have good effects on spasm, gastric secretion inhibition and anti-ulcer caused by anti-acetylcholine of parasympathetic nerve endings.
TIQUIZIUM BROMIDE Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
| dog | ld50 | intraperitoneal | 56700ug/kg (56.7mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| dog | ld50 | intravenous | 14200ug/kg (14.2mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| dog | ld50 | oral | 662mg/kg (662mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| dog | ld50 | subcutaneous | 129mg/kg (129mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| mouse | ld50 | intraperitoneal | 83700ug/kg (83.7mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| mouse | ld50 | intravenous | 10300ug/kg (10.3mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| mouse | ld50 | oral | 578mg/kg (578mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| mouse | ld50 | subcutaneous | 82100ug/kg (82.1mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| rat | ld50 | intraperitoneal | 70500ug/kg (70.5mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| rat | ld50 | intravenous | 11400ug/kg (11.4mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| rat | ld50 | oral | 1177mg/kg (1177mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
| rat | ld50 | subcutaneous | 169mg/kg (169mg/kg) | sense organs and special senses: mydriasis (pupillary dilation): eye | oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982. |
TIQUIZIUM BROMIDE Safety Profile
Poison by subcutaneous, intravenous and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Br−, NOx, and SOx.
Related Products
- TIQUIZIUM BROMIDE
- 71732-11-1
- 7173-51-5
- 71735-16-5
- 71735-19-8
- 71735-23-4
- 71735-28-9
- 71735-32-5
- 71735-34-7
- 7173-54-8
- 7173-57-1
Hot Products
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View