Product Name

  • Name

    triflupromazine

  • EINECS
  • CAS No. 146-54-3
  • Article Data11
  • CAS DataBase
  • Density 1.238g/cm3
  • Solubility 1.762mg/L(24 oC)
  • Melting Point 25°C
  • Formula C18H19 F3 N2 S
  • Boiling Point 427.6°Cat760mmHg
  • Molecular Weight 352.423
  • Flash Point 212.4°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES.
  • Risk Codes
  • Molecular Structure Molecular Structure of 146-54-3 (triflupromazine)
  • Hazard Symbols
  • Synonyms Phenothiazine,10-[3-(dimethylamino)propyl]-2-(trifluoromethyl)- (6CI,8CI); 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine;2-(Trifluoromethyl)promazine; Fluopromazine; Psyquil; Siquil; Trifluopromazine;Triflupromazine
  • PSA 31.78000
  • LogP 5.32480

TRIFLUPROMAZINE Chemical Properties

Product Name: Triflupromazine (CAS NO.146-54-3)


Molecular Formula: C18H19F3N2S
Molecular Weight: 352.4170696g/mol
Mol File: 146-54-3.mol
Einecs: 205-673-6
Boiling point: 427.6 °C at 760 mmHg
Flash Point: 212.4 °C
Density: 1.238 g/cm3
Surface Tension: 39.1 dyne/cm
Enthalpy of Vaporization: 68.26 kJ/mol
Vapour Pressure: 1.62E-07 mmHg at 25°C
XLogP3-AA: 5.2
H-Bond Donor: 0
H-Bond Acceptor: 5

TRIFLUPROMAZINE Toxicity Data With Reference

1.    

dlt-mus-ipr 25 mg/kg

     MUREAV    Mutation Research. 17 (1973),87.
2.    

cyt-mam:kdy 10 mg/L/8H-C

     FCTXAV    Food and Cosmetics Toxicology. 8 (1970),617.
3.    

orl-rat LD50:185 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 36 (1986),797.
4.    

ipr-rat LD50:94 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
5.    

orl-mus LD50:245 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
6.    

ipr-mus LD50:100 mg/kg

     MUREAV    Mutation Research. 17 (1973),87.
7.    

ivn-mus LD50:44 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.

TRIFLUPROMAZINE Consensus Reports

EPA Genetic Toxicology Program.

TRIFLUPROMAZINE Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES.

TRIFLUPROMAZINE Specification

 Triflupromazine ,its CAS NO. is 146-54-3,the synonyms is Dimethyl(3-(2-trifluoromethylphenothiazin-10-yl)propyl)amine ; Fluopromazine ; Triflupromazine ; Trifluoropromazine ; 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)-10h-phenothiazine ; Trifluopromazine ; Vetame .

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