-
Name
Taxine
- EINECS
- CAS No. 12607-93-1
- Density 1.28g/cm3
- Solubility
- Melting Point
- Formula C37H51 N O10
- Boiling Point 747.1°C at 760 mmHg
- Molecular Weight 669.89
- Flash Point 405.6°C
- Transport Information
- Appearance
- Safety Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and parenteral routes. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms
- PSA
- LogP
Taxine Chemical Properties
Product Name: Taxine
The MF of Taxine (CAS NO.12607-93-1) is C35H47NO10.
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The MW of Taxine (CAS NO.12607-93-1) is 641.7484.
Synonyms of Taxine (CAS NO.12607-93-1): Taxin ; Taxine A
Index of Refraction: 1.587
EINECS: 235-716-4
Density: 1.28 g/ml
Flash Point: 405.6 °C
Boiling Point: 747.1 °C
Taxine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LDLo | intraperitoneal | 25mg/kg (25mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| dog | LDLo | intraperitoneal | 9mg/kg (9mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| frog | LDLo | parenteral | 17mg/kg (17mg/kg) | BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| guinea pig | LDLo | intraperitoneal | 14mg/kg (14mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 29, Pg. 310, 1922. |
| guinea pig | LDLo | subcutaneous | 10mg/kg (10mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| mouse | LDLo | intraperitoneal | 11mg/kg (11mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| rabbit | LDLo | intraperitoneal | 6mg/kg (6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: ATAXIA | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| rabbit | LDLo | intravenous | 3mg/kg (3mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BEHAVIORAL: ATAXIA | Quarterly Journal of Pharmacy & Pharmacology. Vol. 5, Pg. 205, 1932. |
| rabbit | LDLo | oral | 22mg/kg (22mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 29, Pg. 310, 1922. |
Taxine Safety Profile
Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and parenteral routes. When heated to decomposition it emits toxic fumes of NOx.
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