Product Name

  • Name

    Tazobactam sodium

  • EINECS 685-629-4
  • CAS No. 89785-84-2
  • Article Data4
  • CAS DataBase
  • Density 1.92 g/cm3
  • Solubility Soluble in water.Soluble in water and methanol.
  • Melting Point 140-147oC
  • Formula C10H12N4O5S . Na
  • Boiling Point 707.1 °C at 760 mmHg
  • Molecular Weight 322.277
  • Flash Point 381.4 °C
  • Transport Information
  • Appearance
  • Safety 22-24/25
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 89785-84-2 (Tazobactam sodium)
  • Hazard Symbols Xi
  • Synonyms 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodiumsalt, (2S,3S,5R)- (9CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt,[2S-(2a,3b,5a)]-;CL 307579;Tazobactam sodium;YTR 830;
  • PSA 133.67000
  • LogP -1.83920

Tazobactam sodium Chemical Properties

MF: C20H19N4NaO5S
MW: 450.44
mp:  140-147°C
storage temp:  Store at 0-5°C
solubility:  H2O: 50 mg/mL, clear, colorless
CAS DataBase Reference: 89785-84-2(CAS DataBase Reference)
NIST Chemistry Reference:89785-84-2 (NIST)
The structure of Tazobactam sodium is:

               
 
 

Tazobactam sodium Uses

1、Tazobactam sodium is mainly used as lactamase inhibitor and it also used with lactam antibiotics to enhance their effect.
2、It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn or Piprataz (manufactured by Gepach International). It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
3、Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.
 

Tazobactam sodium Consensus Reports

Tazobactam sodium is reported in EPA TSCA Inventory. Glycol ether compounds are on the Community Right-To-Know List.

Tazobactam sodium Safety Profile

Hazard Codes:  Xi
Risk Statements:  36/37/38
Safety Statements:  22-24/25-36-26
WGK Germany:  3
RTECS:  XI0191500
 

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