Timolol supplier | CasNO.26839-75-8

Name
Timolol
EINECS 248-032-6
CAS No. 26839-75-8
Article Data19
CAS DataBase
Density 1.224 g/cm³
Solubility slightly sol in water
Melting Point 71.5 - 72.5oC
Formula C₁₃H₂₄N₄O₃S
Boiling Point 487.2 °C at 760 mmHg
Molecular Weight 316.425
Flash Point 248.5 °C
Transport Information
Appearance white crystalline powder
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 2-Propanol,1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-, (S)-(-)-(8CI);2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-,(S)-;(-)-S-Timolol;(-)-Timolol;(S)-Timolol;Arutimol;L-Timolol;Oftensin;Timolol;
PSA 107.98000
LogP 0.95840

Timolol Chemical Properties

Molecular Formula: C₁₃H₂₄N₄O₃S
Molar mass: 316.42 g/mol
Density: 1.224 g/cm³
Flash Point: 248.5 °C
Index of Refraction: 1.548
Boiling Point: 487.2 °C at 760 mmHg
Vapour Pressure: 2.62E-10 mmHg at 25 °C
Structure of Timolol (CAS NO.26839-75-8):

XLogP3-AA: 1.8
H-Bond Donor: 2
H-Bond Acceptor: 7
IUPAC Name: (2S)-1-(tert-Butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
Canonical SMILES: CC(C)(C)NCC(COC1=NSN=C1N2CCOCC2)O
Isomeric SMILES: CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O
InChI: InChI=1S/C13H24N4O3S/c1-13(2,
3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,
1-3H3/t10-/m0/s1
InChIKey: BLJRIMJGRPQVNF-JTQLQIEISA-N

Timolol Uses

In its ophthalmic form (brand names Timoptol in Italy; Timoptic), Timolol (CAS NO.26839-75-8) is used to treat open-angle and occasionally secondary glaucoma by reducing aqueous humour production through blockage of the beta receptors on the ciliary epithelium. In its oral form (Blocadren), it is used to prevent heart attacks and treat high blood pressure , and occasionally to prevent migraine headaches.

Timolol Specification

Timolol ,its cas register number is 26839-75-8. It also can be called Timoptol ; Timacar ; Timoptic ; Optimol and Blocadren . Timolol (CAS NO.26839-75-8) is a non-selective beta-adrenergic receptor blocker. The pharmacological mechanism by which it actually does this is still unknown.The most serious possible side effects include severe bronchospasms and cardiac arrhythmias. It also could lead to fainting, congestive heart failure, confusion, depression, impotence and worsening of Raynaud's syndrome.

Product Name

Timolol

Timolol Chemical Properties

Timolol Uses

Timolol Specification

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