Trifluoromethanesulphenyl chloride supplier

Name
TRIFLUOROMETHYLSULPHENYL CHLORIDE
EINECS
CAS No. 421-17-0
Article Data57
CAS DataBase
Density 1.573g/cm³
Solubility
Melting Point
Formula CCl F3 S
Boiling Point °Cat760mmHg
Molecular Weight 136.525
Flash Point °C
Transport Information
Appearance
Safety Explosive reaction with chlorine fluorides. When heated to decomposition it emits toxic fumes of F⁻, Cl⁻, and SO_x. See also FLUORIDES.
Risk Codes 26-34
Molecular Structure
Hazard Symbols
Synonyms Perfluoromethylsulfenylchloride; Trifluoromethanesulfenyl chloride; Trifluoromethylsulfenyl chloride;Trifluoromethylsulphenyl chloride
PSA 25.30000
LogP 2.39320

Synthetic route

: 7664-39-3
hydrogen fluoride

: 594-42-3
chlorothio-trichloro-methane

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 372-64-5
Bis(trifluoromethyl)disulfid

C: 358-15-6
Trifluoro-methanethiosulfonic acid S-trifluoromethyl ester

Conditions

Conditions	Yield
180°C; chrom oxide fluoride catalyst;	A 74% B n/a C n/a

...Expand

: sodium fluoride

: 594-42-3
chlorothio-trichloro-methane

: 421-17-0
Trifluoromethylsulfenyl chloride

Conditions

Conditions	Yield
In further solvent(s) in tetramethylsulphone at 170-250°C;	47%
In acetonitrile 170-250°C;	47%
In acetonitrile 170-250°C;	47%
In further solvent(s) in tetramethylsulphone at 170-250°C;	47%
In acetonitrile 170-250°C;	47%

: potassium fluoride

: 993-38-4
chlorodifluoromethansulfenylchloride

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 17742-03-9
chlorodifluoromethanesulphenic acid fluoride

Conditions

Conditions	Yield
at 150°C;	A 25% B 5%
at 150°C;	A 25% B 5%

...Expand

: 993-38-4
chlorodifluoromethansulfenylchloride

: 7783-56-4
antimony(III) fluoride

: 421-17-0
Trifluoromethylsulfenyl chloride

Conditions

Conditions	Yield
	11%
	11%

: 993-38-4
chlorodifluoromethansulfenylchloride

: 421-17-0
Trifluoromethylsulfenyl chloride

Conditions

Conditions	Yield
With antimonypentachloride; antimony(III) fluoride

: 372-64-5
Bis(trifluoromethyl)disulfid

: 421-17-0
Trifluoromethylsulfenyl chloride

Conditions

Conditions	Yield
With chlorine Irradiation.bei mehrtaegiger Bestrahlung mit UV-Licht;
With chlorine Irradiation (UV/VIS);
With chlorine Irradiation (UV/VIS);

: 1512-33-0
1,1,1-trifluoromethanesulfenylamine

A: 421-17-0
Trifluoromethylsulfenyl chloride

B S2Cl2, Cl3S3N3: S2Cl2, Cl3S3N3

Conditions

Conditions	Yield
With chlorine at -30℃; for 0.5h; Product distribution;

: 420-32-6
thiocarbonyl fluoride

: 7790-89-8
chlorine monofluoride

: 421-17-0
Trifluoromethylsulfenyl chloride

: sodium fluoride

: 594-42-3
chlorothio-trichloro-methane

A: 993-38-4
chlorodifluoromethansulfenylchloride

B: 421-17-0
Trifluoromethylsulfenyl chloride

...Expand

: CF3SCNCFSSCF3

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 33278-65-8
trifluoromethylcarbamoyldisulfane

Conditions

Conditions	Yield
With hydrogenchloride; water byproducts: HF;
With HCl; H2O byproducts: HF;

: 5813-48-9
Methanesulfenyl chloride

: 17742-04-0
trifluoromethylsulfenyl fluoride

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 14410-21-0
trifluoromethyl disulphide

C: 65082-47-5
Methylsulfur trifluoride

Conditions

Conditions	Yield
-50°C;
-50°C;

...Expand

: 1512-33-0
1,1,1-trifluoromethanesulfenylamine

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: ammonium chloride

Conditions

Conditions	Yield
With hydrogenchloride
With HCl

: 691-03-2
trifluoromethylmercaptoisocyanate

: 763-24-6
bis(trifluoromethylthio) amine

: 2712-93-8
dichlorofluoromethanesulphenyl chloride

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 34153-27-0
trifluoromethylmercapto-bis(dichlorofluoromethylmercapto)amine

C: 593-81-7
trimethylamine hydrochloride

...Expand

: 17742-03-9
chlorodifluoromethanesulphenic acid fluoride

: 421-17-0
Trifluoromethylsulfenyl chloride

Conditions

Conditions	Yield
room temp.;

: 993-38-4
chlorodifluoromethansulfenylchloride

: 691-03-2
trifluoromethylmercaptoisocyanate

: 763-24-6
bis(trifluoromethylthio) amine

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 34153-25-8
trifluoromethylmercapto-bis(chlorodifluoromethylmercapto)amine

C: 593-81-7
trimethylamine hydrochloride

...Expand

: 594-42-3
chlorothio-trichloro-methane

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 372-64-5
Bis(trifluoromethyl)disulfid

C: 812-12-4
trifluoromethanesulfinyl fluoride

Conditions

Conditions	Yield
fluorination;
fluorination;

...Expand

: 6080-81-5
trifluoromethylmercapto carbamic acid chloride

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 6417-75-0
14,14,14-Trifluor-13-thia-2,4,6,8,10,12-hexaaza-tetradecan-pentaon-(3,5,7,9,11)-saeurechlorid

Conditions

Conditions	Yield
20°C;
20°C;

: 42016-33-1
N-Chlor-bis(fluorcarbonyl)-amin

: 21259-75-6
mercury bis(trifluoromethanethiolate)

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: Hg(2+)*(FCO)2N(1-)*SCF3(1-)=(FCO)2NHgSCF3

...Expand

: 21259-75-6
mercury bis(trifluoromethanethiolate)

: 7782-50-5
chlorine

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: 372-64-5
Bis(trifluoromethyl)disulfid

C: trifluoromethylthio-mercury(II) chloride

Conditions

Conditions	Yield
-22°C;

...Expand

: 36668-60-7
N,N'-bis(trifluoromethylmercapto)-chloroformamidine

: 36668-61-8
N,N,N'-tris(trifluoromethylmercapto)-chloroformamidine

A: 421-17-0
Trifluoromethylsulfenyl chloride

B: (CF3S)2NCN

C: 36757-19-4
hexakis(trifluoromethylmercapto)melamine

Conditions

Conditions	Yield
With trimethylamine	A n/a B 0% C n/a
With (CH3)3N	A n/a B 0% C n/a

...Expand

: 421-17-0
Trifluoromethylsulfenyl chloride

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 374-10-7
trifluoro(trifluoromethyl)sulfur(IV)

Conditions

Conditions	Yield
at -78°C, 0.5 h;	100%
at -78°C, 0.5 h;	100%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 10181-78-9
N-chlorobistrifluoromethylketimine

: 31340-34-8
trifuloromethylsulfur perfluoroisopropylideneamide

Conditions

Conditions	Yield
With mercury in Carius tube;	100%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 7732-18-5
water

: 7782-50-5
chlorine

: 421-83-0
trifluoromethane sulfonyl chloride

Conditions

Conditions	Yield
excess of Cl2 and H2O, 20°C, 7 days;	98%
excess of Cl2 and H2O, 20°C, 7 days;	98%

...Expand

: 421-17-0
Trifluoromethylsulfenyl chloride

: 124824-09-5
bis(sulfinylamido)tellurane

: 160785-74-0
bis(sulfinylamido) tellurium(IV) chloride

Conditions

Conditions	Yield
In dichloromethane byproducts: CF3SSCF3; 2 equiv. of CF3SCl was condensed to Te-compd., stirred for 12 h at -60 ° C; volatiles were removed in vac., solid was dried in vac. for 12 h at 20 °C.;	97%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 141-78-6
ethyl acetate

: 42105-37-3
ethyl esetrs of α-(trifluoromethylthio)acetic acid

Conditions

Conditions	Yield
-20 to +24°C;	96%
-20 to +24°C;	96%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 160785-74-0
bis(sulfinylamido) tellurium(IV) chloride

: Te2Cl5N

Conditions

Conditions	Yield
In dichloromethane byproducts: SO2, CF3SSCF3; Te-compd. and CF3SCl in 1:2 molar ratio were stirred for 12 h at 22 ° C; volatiles were detected by IR;	96%
In dichloromethane byproducts: SO2, CF3SNSO; 1 equiv. of CF3SCl was condensed to Te-compd., stirred for 3 d at -15 ° C; volatiles were identified by GC-MS and (19)F NMR;	95%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 110-83-8
cyclohexene

: rac-(1R,2R)-1-chloro-2-[(trifluoromethyl)sulfanyl]cyclohexane

Conditions

Conditions	Yield
trifluoroacetic acid at -20℃;	95%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 83665-28-5
bis(trifluoromethylthio)tellurium

Conditions

Conditions	Yield
With bis(triphenylstannyl)tellurium In various solvent(s) at 20℃; for 4h;	95%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 7790-91-2
chlorine trifluoride

: 374-10-7
trifluoro(trifluoromethyl)sulfur(IV)

Conditions

Conditions	Yield
In dichloromethane -78°C;	95%
In dichloromethane -78°C;	95%
In further solvent(s) in CF2Cl2 at -196 to -78°C;
In further solvent(s) in CF2Cl2 at -196 to -78°C;

: 421-17-0
Trifluoromethylsulfenyl chloride

: 20621-29-8
trifluoromethylsulfinyl chloride

Conditions

Conditions	Yield
With m-chloroperbenzoic acid oxidn., from -20 to +25°C, 12 h;	95%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 75264-94-7
Trifluormethylselenosilber

: 73076-98-9
trifluoromethyl trifluoromethanesulfenoselenoate

Conditions

Conditions	Yield
at -60℃;	93%
-60°C;	93-94

: 421-17-0
Trifluoromethylsulfenyl chloride

: 23787-16-8
β-aminocinnamic amide

: β-amino-α-trifluoromethylthio-cinnamic acid amide

Conditions

Conditions	Yield
In chloroform Heating; 0 deg C, 30 min, room temperature, 20 h;	90%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 16187-90-9
β-imino-β-phenylpropionitrile

: β-amino-α-trifluoromethylthio-cinnamic acid nitrile

Conditions

Conditions	Yield
In chloroform Heating; 0 deg C, 30 min, room temperature, 20 h;	90%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 540-59-0
1,2-Dichloroethylene

: 40302-61-2
Trifluormethyl-1,2,2-trichlorethyl-sulfid

Conditions

Conditions	Yield
Irradiation (UV/VIS); 3:2 cis-trans isomer 1,2-dichloroethylene; distn.;	90%
Irradiation (UV/VIS); 3:2 cis-trans isomer 1,2-dichloroethylene; distn.;	90%
	80%
	80%

: 421-17-0
Trifluoromethylsulfenyl chloride

: silver fluoride

A: 17742-04-0
trifluoromethylsulfenyl fluoride

B: 26391-89-9
difluoro(trifluoromethyl)trifluormethylsulfanylsulfur(IV)

Conditions

Conditions	Yield
at 100°C;	A 10% B 90%
at 100°C;	A 10% B 90%

...Expand

: 421-17-0
Trifluoromethylsulfenyl chloride

: Hg(2+)*Cl(1-)*OC(CF3)3(1-)=HgCl{OC(CF3)3}

: 66700-53-6
Perfluor-tert.-butyl-trifluormethansulfenat

Conditions

Conditions	Yield
with Hg(Cl)OC(CF3)3 excess at 0°C (24 h);	90%
excess of (CF3)3COHgCl, 24 h, 0°C;	90%
with Hg(Cl)OC(CF3)3 excess at 0°C (24 h);	90%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 292638-85-8
acrylic acid methyl ester

A: CF3SCH2CHClCO2CH3

B: 34033-72-2
α-(Trifluormethylthio)-β-chlorpropionat

C: 34033-73-3
2-Chloromethyl-4-trifluoromethylsulfanyl-pentanedioic acid dimethyl ester

Conditions

Conditions	Yield
CF3SCl excess; gas chromy. and (19)F-NMR detection;	A 10% B 90% C n/a
CF3SCl excess; gas chromy. and (19)F-NMR detection;	A 10% B 90% C n/a

...Expand

: 421-17-0
Trifluoromethylsulfenyl chloride

: 22089-64-1
N-Sulfinyl-trifluormethansulfenamid

Conditions

Conditions	Yield
With N-sulfinyl trimethylsilanamine at 0℃; for 4h; ultrasound;	89%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 54393-47-4
Se,Se-bis(trifluoromethyl) carbonodiselenothioate

: Bis(trifluormethylselenyl)chlormethyl-trifluormethyldisulfan

Conditions

Conditions	Yield
for 2h; Irradiation;	88%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 3446-58-0
3-oxo-3-phenylpropanamide

A: α,α-bis(trifluoromethylthio)benzoylacetic acid amide

B: 116073-28-0
α-trifluoromethylthio-benzoylacetic acid amide

Conditions

Conditions	Yield
In chloroform Heating; 0 deg C, 30 min, room temperature, 20 h;	A 4% B 88%

...Expand

: 421-17-0
Trifluoromethylsulfenyl chloride

: 66224-66-6, 66224-67-7, 66224-68-8, 66224-69-9, 134434-48-3, 134434-49-4, 134454-76-5, 134461-75-9
adenine

: 55055-52-2
C5N4H3NHSCF3

Conditions

Conditions	Yield
In tetrahydrofuran 20°C for 1.5 h, Carius tube;	88%
In tetrahydrofuran 20°C for 1.5 h, Carius tube;	88%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 93383-98-3
Bis<2,2,4,4-tetrakis(trifluormethyl)-4H-1,3,5-dioxazin-6-ylthio>quecksilber

: 103191-46-4
<2,2,4,4-Tetrakis(trifluormethyl)-4H-1,3,5-dioxazin-6-yl>(trifluormethyl)disulfan

Conditions

Conditions	Yield
In dichloromethane at -196℃; for 12h;	87%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 67-64-1
acetone

: 42105-30-6
1-trifluoromethylthio-2-propanone

Conditions

Conditions	Yield
bomb tube (-80 to +20°C);	86%
bomb tube (-80 to +20°C);	86%
	71%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 126-81-8
dimedone

: 128402-12-0
2-(trifluoromethylthio)-5,5-dimethyl-1,3-cyclohexanedione

Conditions

Conditions	Yield
With pyridine In chloroform Ambient temperature;	86%

: 421-17-0
Trifluoromethylsulfenyl chloride

: bis(trifluoromethylthio)selenide

Conditions

Conditions	Yield
With dmap; hydrogen selenide In dichloromethane at -78℃; for 3h;	86%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 1000815-86-0
5-amino-1-(2-chloro-6-fluoro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile

: 1000815-85-9
5-amino-3-cyano-1-(2-chloro-6-fluoro-4-trifluoromethylphenyl)-4-trifluoro-methylthiopyrazole

Conditions

Conditions	Yield
Stage #1: Trifluoromethylsulfenyl chloride; 5-amino-1-(2-chloro-6-fluoro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile In dichloromethane at 0 - 25℃; Stage #2: With sodium hydrogencarbonate In dichloromethane; water	86%

: 638-02-8
2,5-DIMETHYLTHIOPHENE

: 421-17-0
Trifluoromethylsulfenyl chloride

: 60830-50-4
2,5-dimethyl-3-trifluoromethylsulfanyl-thiophene

Conditions

Conditions	Yield
tin(IV) chloride	86%
tin(IV) chloride	86%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 71940-96-0
silver-2,3,4,5-tetrakis(trifluoromethylsulfanyl)-1H-pyrrolide

: 87840-93-5
1,2,3,4,5-Pentakis(trifluoromethylthio)pyrrole

Conditions

Conditions	Yield
at 20℃; for 24h;	85%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 55047-82-0
N-silver(I) succinimide

: 1-((trifluoromethyl)thio)pyrrolidine-2,5-dione

Conditions

Conditions	Yield
In diethyl ether 1) -78 deg C to 20 deg C, 16 h, 2) 20 deg C, 24 h;	85%

: 421-17-0
Trifluoromethylsulfenyl chloride

: 23384-33-0
1,1,1-trifluoro-N-(3-methoxyphenyl)methanesulfonamide

: 66476-52-6
N-(Trifluormethyl-sulfonyl)-4,6-bis-(trifluormethylthio)-3-methoxy-anilin

Conditions

Conditions	Yield
In pyridine; chloroform -40°C;	85%
In pyridine; chloroform -40°C;	85%

Trifluoromethanesulphenyl chloride Chemical Properties

Trifluoromethanesulfonyl chloride(421-17-0)'s molecular formula is CClF₃S and its formula weight is 136.52.
Trifluoromethanesulfonyl chloride(421-17-0)'s chemical synonyms are Methanesulfenyl chloride, trifluoro-;Perfluoromethylsulfenyl chloride;perfluoromethylsulfenylchloride;trifluoro-methanesulfenylchlorid;trifluoromethanesulfenylchloride;trifluoromethane-sulfenylchloride;TRIFLUOROMETHYLSULFENYL CHLORIDE;TRIFLUOROMETHYLSULPHENYL CHLORIDE
The molecular structure of trifluoromethanesulfonyl chloride(421-17-0):

Trifluoromethanesulphenyl chloride Safety Profile

Explosive reaction with chlorine fluorides. When heated to decomposition it emits toxic fumes of F⁻, Cl⁻, and SO_x. See also FLUORIDES.
Hazard Codes T
Risk Statements 26-34
Safety Statements 23-24/25-26-36/37/39-45
RIDADR 3308
Hazard Note Highly Toxic/Lachrymatory

Trifluoromethanesulphenyl chloride Specification

Descriptors Computed from Structure
IUPAC Name: trifluoromethyl thiohypochlorite(421-17-0)
Canonical SMILES: C(F)(F)(F)SCl
InChI: InChI=1/CClF3S/c2-6-1(3,4)5

Product Name

TRIFLUOROMETHYLSULPHENYL CHLORIDE

Synthetic route

Trifluoromethanesulphenyl chloride Chemical Properties

Trifluoromethanesulphenyl chloride Safety Profile

Trifluoromethanesulphenyl chloride Specification

Related Products

Hot Products