Product Name

  • Name

    gamma-Oryzanol

  • EINECS 244-285-1
  • CAS No. 11042-64-1
  • Density 1.1 g/cm3
  • Solubility soluble in acetone, chloroform; sparingly soluble in ethanol and n-heptane; insoluble in water
  • Melting Point 135-137 ºC
  • Formula C40H58O4
  • Boiling Point 663.2 ºC at 760 mmHg
  • Molecular Weight 602.98
  • Flash Point 193.8 ºC
  • Transport Information
  • Appearance White or white crystalline powder, odourless
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 11042-64-1 (gamma-Oryzanol)
  • Hazard Symbols
  • Synonyms Gamma oryzanol;Oryzanol;CCRIS 4251;Gammariza;HI-Z;OZ;Oliver;UNII-SST9XCL51M;9,19-Cyclo-9beta-lanost-24-en-3beta-ol 4-hydroxy-3-methoxycinamate;
  • PSA 55.76000
  • LogP 10.14740

gamma-Oryzanol Specification

The γ-Oryzanol, with the CAS registry number 11042-64-1, has the product categories which are including Aromatic Esters; Nutritional Supplements. Besides, it is usually applied in curing many diseases, such as periodic psychosis, premenstrual tension, women's Menopause Syndrome, vascular headache, and dysfunction of autonomic nervoussystem.

The characteristics of this chemical are as below: (1)ACD/LogP: 12.85; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): 12.85; (4)ACD/LogD (pH 7.4): 12.85; (5)#H bond acceptors: 4; (6)#H bond donors: 1; (7)#Freely Rotating Bonds: 10; (8)Polar Surface Area: 44.76; (9)Index of Refraction: 1.569; (10)Molar Refractivity: 178.62 cm3; (11)Molar Volume: 544.6 cm3; (12)Polarizability: 70.81×10-24 cm3; (13)Surface Tension: 46.2 dyne/cm; (14)Density: 1.1 g/cm3; (15)Flash Point: 193.8 °C; (16)Enthalpy of Vaporization: 101.08 kJ/mol; (17)Boiling Point: 663.2 °C at 760 mmHg; (18)Vapour Pressure: 3.38E-18 mmHg at 25°C; (19)Exact Mass: 602.43351; (20)MonoIsotopic Mass: 602.43351; (21)Topological Polar Surface Area: 55.8; (22)Heavy Atom Count: 44; (23)Complexity: 1150.

In adddition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: CC(CCC=C(C)C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(C5(C)C)OC(=O)C=CC6=CC(=C(C=C6)O)OC)C)C
(2)Isomeric SMILES: C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2([C@@]1(CC[C@]34[C@H]2CC[C@@H]5[C@]3(C4)CC[C@@H](C5(C)C)OC(=O)/C=C/C6=CC(=C(C=C6)O)OC)C)C
(3)InChI: InChI=1S/C40H58O4/c1-26(2)10-9-11-27(3)29-18-20-38(7)33-16-15-32-36(4,5)34(19-21-39(32)25-40(33,39)23-22-37(29,38)6)44-35(42)17-13-28-12-14-30(41)31(24-28)43-8/h10,12-14,17,24,27,29,32-34,41H,9,11,15-16,18-23,25H2,1-8H3/b17-13+/t27-,29-,32+,33+,34+,37-,38+,39-,40+/m1/s1
(4)InChIKey: FODTZLFLDFKIQH-FSVGXZBPSA-N 

Below are the toxicity information of this chemical:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 5gm/kg (5000mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 2401, 1978.
guinea pig LD50 skin 100mg/kg (100mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 7, Pg. 1295, 1979.
mouse LD intramuscular > 500mg/kg (500mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 2781, 1973.
mouse LD intraperitoneal > 10gm/kg (10000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 2781, 1973.
mouse LD subcutaneous > 2500mg/kg (2500mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 2781, 1973.
mouse LD50 intravenous 811mg/kg (811mg/kg)   Drugs in Japan Vol. -, Pg. 297, 1995.
mouse LD50 oral > 25gm/kg (25000mg/kg)   Drugs in Japan Vol. -, Pg. 297, 1995.
rabbit LD oral > 5gm/kg (5000mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 2401, 1978.
rabbit LD subcutaneous > 2500mg/kg (2500mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 2401, 1978.
rat LD intramuscular > 500mg/kg (500mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 2781, 1973.
rat LD subcutaneous > 1gm/kg (1000mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 2781, 1973.
rat LD50 intravenous 382mg/kg (382mg/kg)   Drugs in Japan Vol. -, Pg. 297, 1995.
rat LD50 oral > 25gm/kg (25000mg/kg)   Drugs in Japan Vol. -, Pg. 297, 1995.
rat LD50 skin 100mg/kg (100mg/kg)   Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 7, Pg. 1295, 1979.
rat LDLo intraperitoneal 1250mg/kg (1250mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 2781, 1973.

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View