L-Proline, 4-hydroxy-1-nitroso-, (4R)- (9CI)

IUPAC Name: (2S,4R)-4-Hydroxy-1-nitrosopyrrolidine-2-carboxylic acid 
Molecular Formula: C₅H₈N₂O₄
Molecular Weight: 160.15
Density: 1.79g/cm³
Boiling Point: 482.7°C at 760mmHg
Flash Point: 245.7°C 
Freely Rotating Bonds: 3
Polar Surface Area: 68.2 Å²
Index of Refraction: 1.674
Molar Refractivity: 33.45 cm³
Molar Volume: 89 cm³
Polarizability: 13.26 ×10^-24 cm³
Surface Tension: 83.3 dyne/cm
Enthalpy of Vaporization: 86.15 kJ/mol
Vapour Pressure: 2.42E-11 mmHg at 25°C
The Cas Register Number  of trans-4-Hydroxy-1-nitroso-l-proline is 30310-80-6.The chemical synonyms of trans-4-Hydroxy-1-nitroso-l-proline (CAS NO.30310-80-6) are Nitrosohydroxyproline ; N-Nitrosohydroxyproline ; 4-hydroxy-1-nitrosoproline ; trans-4-Hydroxy-1-nitroso-L-proline ; Proline, 4-hydroxy-1-nitroso-, L- ; CID61873 ; BRN 0475250 ; NSC109547 ; (4R)-4-hydroxy-1-nitroso-L-proline ; LS-7604 .Product categories of trans-4-Hydroxy-1-nitroso-l-proline (CAS NO.30310-80-6) are  PYRROLE .The molecular structure of trans-4-Hydroxy-1-nitroso-l-proline (CAS NO.30310-80-6) is.

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 17 , 1978,p. 303.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Questionable carcinogen. When heated to decomposition it emits toxic fumes of NO_x.

  trans-4-Hydroxy-1-nitroso-l-proline (CAS NO.30310-80-6), an important component of collagen, was transformed into its N-nitroso-derivative, (4R)-4-hydroxy-1-nitroso-l-proline, 1 by butylnitrite in the acidic medium. The structure is a cyclic hydroxy-N-nitrosoacid with the carboxyl and hydroxyl groups trans to each other.