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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 106131-61-7 with competitive price

Cas:106131-61-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

Dichloro-S-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:106131-61-7

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1,2,4,5-Tetrazine, 3,6-dichloro-

Cas:106131-61-7

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ 3,6-dichloro-1,2,4,5-tetrazine /Manufacturer in China

Cas:106131-61-7

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, in

Enke Dichloro-s-tetrazine

Cas:106131-61-7

Min.Order:1 Kilogram

FOB Price: $300.0 / 400.0

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

1,2,4,5-Tetrazine, 3,6-dichloro-

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 3,6-Dichloro-1,2,4,5-tetrazine 5g

Cas:106131-61-7

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

1,2,4,5-Tetrazine, 3,6-dichloro-

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

factory?direct?sale Application:healing drugs

1,2,4,5-Tetrazine, 3,6-dichloro-

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Chemical intermediate

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,6-Dichloro-[1,2,4,5]tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3,6-Dichloro-1,2,4,5-tetrazine 106131-61-7

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Scochem Technology Co., Ltd.

High quality suppliers Application:healing drugs

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

3,6-Dichloro-1,2,4,5-tetrazine 106131-61-7

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

3,6-Dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Changzhou Extraordinary Pharmatech co.,LTD

Changzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa

1,2,4,5-Tetrazine, 3,6-dichloro-

Cas:106131-61-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

106131-61-7

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

nanjing bam biomedical technology co.,ltd

It is composed of professionals with senior industry background and rich market experience. More than 90% of the personnel have chemistry, chemical, pharmaceutical or related professional knowledge. They are all rigorously trained and evaluated, and

dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Zhiyan Pharmaceutical Technology Co. Ltd.

High quality / commercialize;Stable production capacity.Appearance:actual character Storage:Temperature controlled NMT 30℃ Package:As customer request Application:Used for Synthesis API and Research Transportation:Follow the MSDS

dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Reply quotation within 2 hours.Guarantee the time of delivery. Update the progress of customization Weekly.High purity& High product customization success rate.Inquiries for other compounds are acceptable. Storage:refrigeration Package:1g,5g,10g,100g

dichloro-1,2,4,5-tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Norris Pharm Technology Co., Ltd.

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3,6-Dichloro-[1,2,4,5]tetrazine

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Run-Biotech Co., Ltd.

Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

1,2,4,5-Tetrazine, 3,6-dichloro-

Cas:106131-61-7

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

3,6-dihydrazinyl-1,2,4,5-tetrazine
5940-53-4

3,6-dihydrazinyl-1,2,4,5-tetrazine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

Conditions
ConditionsYield
With trichloroisocyanuric acid In acetonirile at 0 - 20℃;81%
With trichloroisocyanuric acid In acetonitrile at 0 - 20℃; for 0.833333h; Inert atmosphere;68%
With trichloroisocyanuric acid In acetonitrile at 0 - 20℃; for 0.333333h;67%
3,6-dimethylthio-1,2,4,5-tetrazine
1672-34-0

3,6-dimethylthio-1,2,4,5-tetrazine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

Conditions
ConditionsYield
68%
3,6-bis-(3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazine
30169-25-6

3,6-bis-(3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

Conditions
ConditionsYield
Stage #1: 3,6-bis-(3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazine With hydrazine
Stage #2: With chlorine
[1,2,4,5]tetrazinane-3,6-dione dihydrazone
5940-11-4

[1,2,4,5]tetrazinane-3,6-dione dihydrazone

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

Conditions
ConditionsYield
With trichloroisocyanuric acid In acetonitrile at 0 - 20℃; for 0.333333h;
N,N-bis(4-bromophenyl)-4-hydroxyphenylamine
336619-79-5

N,N-bis(4-bromophenyl)-4-hydroxyphenylamine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-{4-[bis(4-bromophenyl)amino]phenoxy}-6-chloro-1,2,4,5-tetrazine
1374356-14-5

3-{4-[bis(4-bromophenyl)amino]phenoxy}-6-chloro-1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 1h;100%
N-aminopyridin-1-ium iodide
6295-87-0

N-aminopyridin-1-ium iodide

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

(6-chloro-1,2,4,5-tetrazin-3-yl)(pyridin-1-ium-1-yl)amide

(6-chloro-1,2,4,5-tetrazin-3-yl)(pyridin-1-ium-1-yl)amide

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 23℃; for 3h;99%
9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
298-81-7

9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

2-chloro-6-methoxypyridazino[4,3-h]psoralen
647021-08-7

2-chloro-6-methoxypyridazino[4,3-h]psoralen

Conditions
ConditionsYield
Stage #1: 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 3,6-dichloro-1,2,4,5-tetrazine In dichloromethane at 140℃;
Stage #2: With N-ethyl-N,N-diisopropylamine
98%
morpholine
110-91-8

morpholine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

4-(6-chloro-1,2,4,5-tetrazin-3-yl)morpholine
106131-66-2

4-(6-chloro-1,2,4,5-tetrazin-3-yl)morpholine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 1h;97%
With N-ethyl-N,N-diisopropylamine In tert-butyl methyl ether at 20℃; for 21h; Inert atmosphere;87%
In various solvent(s) at 20℃;83%
(4-(di-tert-butylfluorosilyl)phenyl)methanol
1146956-36-6

(4-(di-tert-butylfluorosilyl)phenyl)methanol

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-((4-(di-tert-butylfluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine

3-chloro-6-((4-(di-tert-butylfluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere;95%
With 2,4,6-trimethyl-pyridine In dichloromethane for 0.583333h; Inert atmosphere;95%
[18F]-SiFA-OH

[18F]-SiFA-OH

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

C17H24Cl(18)FN4OSi

C17H24Cl(18)FN4OSi

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane for 0.25h;95%
N-acetylcystein
616-91-1

N-acetylcystein

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3,6-bis-S,S'-(NHAc-Cys-OH)tetrazine
1234326-41-0

3,6-bis-S,S'-(NHAc-Cys-OH)tetrazine

Conditions
ConditionsYield
With ammonium bicarbonate In 1,4-dioxane; water for 1h; Inert atmosphere; Darkness;93%
In acetonitrile at 80℃; for 24h; Kinetics; Solvent; pH-value; Temperature; Inert atmosphere;49%
4-(di-tert-butylfluorosilanyl)benzenethiol
1112840-20-6

4-(di-tert-butylfluorosilanyl)benzenethiol

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-((4-(di-tert-butylfluorosilyl)phenyl)-thio)-1,2,4,5-tetrazine

3-chloro-6-((4-(di-tert-butylfluorosilyl)phenyl)-thio)-1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 0.666667h; Inert atmosphere;93%
1-ferrocenylmethanol
1273-86-5

1-ferrocenylmethanol

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-(ferrocenemethoxy)-1,2,4,5-tetrazine

3-chloro-6-(ferrocenemethoxy)-1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane for 0.666667h; Inert atmosphere;93%
4,4'-(s-tetrazine-3,6-diyl)bis(oxy)dibutan-1-ol
907560-43-4

4,4'-(s-tetrazine-3,6-diyl)bis(oxy)dibutan-1-ol

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3,6-bis(4-(6-chloro-1,2,4,5-tetrazin-3-yloxy)butoxy)-1,2,4,5-s-tetrazine
1040376-29-1

3,6-bis(4-(6-chloro-1,2,4,5-tetrazin-3-yloxy)butoxy)-1,2,4,5-s-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane Inert atmosphere;92%
1,2,4-Triazole
288-88-0

1,2,4-Triazole

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3,6-bis(1,2,4-triazolyl-1-yl)1,2,4,5-tetrazine
1612764-65-4

3,6-bis(1,2,4-triazolyl-1-yl)1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In acetonitrile at 0 - 20℃; for 1h;92%
In acetone; acetonitrile for 20h; Reflux;83%
C17H30N4O7S

C17H30N4O7S

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

(R)-2,2'-(7-(1-carboxy-4-((2-((6-chloro-1,2,4,5-tetrazin-3-yl)thio)ethyl)amino)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid

(R)-2,2'-(7-(1-carboxy-4-((2-((6-chloro-1,2,4,5-tetrazin-3-yl)thio)ethyl)amino)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 0.5h;91%
(2-aminomethylpyridine)
3731-51-9

(2-aminomethylpyridine)

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

C8H7ClN6

C8H7ClN6

Conditions
ConditionsYield
In tert-butyl methyl ether at 20℃; for 12h;91%
(S)-2,2'-(7-(1-carboxy-4-((2-mercaptoethyl)amino)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid

(S)-2,2'-(7-(1-carboxy-4-((2-mercaptoethyl)amino)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

(S)-2,2'-(7-(1-carboxy-4-((2-((6-chloro-1,2,4,5-tetrazin-3-yl)thio)ethyl)amino)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid

(S)-2,2'-(7-(1-carboxy-4-((2-((6-chloro-1,2,4,5-tetrazin-3-yl)thio)ethyl)amino)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 0.166667h;91%
2',3'-O-isopropylideneuridine
362-43-6

2',3'-O-isopropylideneuridine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

5′-O-(6-chloro-1,2,4,5-tetrazin-3-yl)-2′,3′-O-isopropylideneuridine

5′-O-(6-chloro-1,2,4,5-tetrazin-3-yl)-2′,3′-O-isopropylideneuridine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 16.5h;90%
3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

diethylamine
109-89-7

diethylamine

3-chloro-6-diethylaminotetrazine
614756-32-0

3-chloro-6-diethylaminotetrazine

Conditions
ConditionsYield
In various solvent(s) at 20℃;89%
t-butyl mercaptoacetate
20291-99-0

t-butyl mercaptoacetate

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

1,2,4,5-tetrazine-3,6-di-tert-butyldithioglycolic ester

1,2,4,5-tetrazine-3,6-di-tert-butyldithioglycolic ester

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃;89%
3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

thioredoxin

thioredoxin

tetrazine Stapled thioredoxin

tetrazine Stapled thioredoxin

Conditions
ConditionsYield
Stage #1: thioredoxin With tris(2-carboxyethyl)phosphine immobilized on agrose at 20℃; for 2h; pH=5; Inert atmosphere;
Stage #2: 3,6-dichloro-1,2,4,5-tetrazine In dimethyl sulfoxide pH=5; Inert atmosphere;
88%
piperidine
110-89-4

piperidine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-(piperidin-1-yl)-1,2,4,5-tetrazine

3-chloro-6-(piperidin-1-yl)-1,2,4,5-tetrazine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tert-butyl methyl ether at 20℃; for 21h; Inert atmosphere;88%
4-hydroxyltriphenylamine
25069-86-7

4-hydroxyltriphenylamine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-[4-(diphenylamino)phenoxy]-1,2,4,5-tetrazine
1374356-15-6

3-chloro-6-[4-(diphenylamino)phenoxy]-1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃; for 1h;87%
tetraethylene glycol monomethyl ether
23783-42-8

tetraethylene glycol monomethyl ether

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

C11H19ClN4O5

C11H19ClN4O5

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 3h;87%
3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

4,4,5,5-tetramethyl-2-trimethylsilanylethynyl-[1,3,2]dioxaborolane
159087-46-4

4,4,5,5-tetramethyl-2-trimethylsilanylethynyl-[1,3,2]dioxaborolane

3,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trimethylsilyl)pyridazine
919197-91-4

3,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trimethylsilyl)pyridazine

Conditions
ConditionsYield
In xylene for 24h; Heating;86%
In xylene 3,6-dichlorotetrazine reacted with B compd. in xylenes under reflux for 24 h;86%
di(d5-phenyl)acetylene-1,2-13C2

di(d5-phenyl)acetylene-1,2-13C2

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3,6-dichloro-4,5-di(d5-phenyl)pyridazine-4,5-13C2

3,6-dichloro-4,5-di(d5-phenyl)pyridazine-4,5-13C2

Conditions
ConditionsYield
In toluene at 180℃; for 6h; Microwave irradiation;86%
4-(2-aminoethyl)-1-(phenylmethyl)piperidine
86945-25-7

4-(2-aminoethyl)-1-(phenylmethyl)piperidine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

N-(2-(1-benzylpiperidin-4-yl)ethyl)-6-chloro-1,2,4,5-tetrazin-3-amine

N-(2-(1-benzylpiperidin-4-yl)ethyl)-6-chloro-1,2,4,5-tetrazin-3-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In tert-butyl methyl ether at 20℃; for 21h; Inert atmosphere;86%
1-(cyclopent-2-en-1-yl)pyrrolidine

1-(cyclopent-2-en-1-yl)pyrrolidine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

1,4-dichloro-6,7-dihydro-5H-cyclopenta[d]pyridazine
91846-80-9

1,4-dichloro-6,7-dihydro-5H-cyclopenta[d]pyridazine

Conditions
ConditionsYield
In dichloromethane for 0.0833333h;86%
methanol
67-56-1

methanol

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3,6-bis(methoxy)-1,2,4,5-tetrazine
81930-31-6

3,6-bis(methoxy)-1,2,4,5-tetrazine

Conditions
ConditionsYield
With hydrogen carbonate Heating;85%
With sodium carbonate; magnesium sulfate at 25 - 65℃;30.8%
methanol
67-56-1

methanol

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-methoxy-1,2,4,5-tetrazine

3-chloro-6-methoxy-1,2,4,5-tetrazine

Conditions
ConditionsYield
at 20℃; for 1h;85%
at 20℃; for 1h;82%
at 20℃; for 1h;75%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 1h; Inert atmosphere;70%
guanazole
1455-77-2

guanazole

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

1,1′-(1,2,4,5-tetrazine-3,6-diyl)-bis(1H-1,2,4-triazole-3,5-di-amine)
1612764-66-5

1,1′-(1,2,4,5-tetrazine-3,6-diyl)-bis(1H-1,2,4-triazole-3,5-di-amine)

Conditions
ConditionsYield
In N,N-dimethyl-formamide; acetonitrile at 20℃; for 2h;85%
In acetonitrile
N-benzyltryptamine
4307-98-6

N-benzyltryptamine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

N10-[6-chloro-3-(1,2,4,5-tetrazinyl)]-N1-benzyltryptamine
264619-99-0

N10-[6-chloro-3-(1,2,4,5-tetrazinyl)]-N1-benzyltryptamine

Conditions
ConditionsYield
In dichloromethane for 2h; Substitution; Heating;83%
N,N-di-(4-methoxy-1',1''-biphenyl)-N-(4-[2'-ethanol]biphenyl)amine

N,N-di-(4-methoxy-1',1''-biphenyl)-N-(4-[2'-ethanol]biphenyl)amine

3,6-dichloro-1,2,4,5-tetrazine
106131-61-7

3,6-dichloro-1,2,4,5-tetrazine

3-chloro-6-([4''-([4'''-(dimethoxy)-1,1'-biphenyl]amine)-1',1''-biphenyl]ethoxy)-1,2,4,5-tetrazine

3-chloro-6-([4''-([4'''-(dimethoxy)-1,1'-biphenyl]amine)-1',1''-biphenyl]ethoxy)-1,2,4,5-tetrazine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine In dichloromethane at 20℃;83%

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