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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

2-(5-Amino-2,4-Dichlorophenyl)-4-(Difluoromethyl)-2,4-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One CAS 111992-18-8

Cas:111992-18-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl- 111992-18-8

Cas:111992-18-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one) CAS:111992-18-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

2-(5-Amino-2,4-Dichlorophenyl)-4-(Difluoromethyl)-2,4-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

2-(5-Amino-2,4-Dichlorophenyl)-4-(Difluoromethyl)-2,4-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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DB BIOTECH CO., LTD

best seller Application:API

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-(5-Amino-2,4-Dichlorophenyl)-4-(Difluoromethyl)-2,4-Dihydro-5-Methyl-3H-1,2,4-Triazol-3-One

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Step 6 (5-amine)

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Other

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

111992-18-8

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Changzhou Pesan Chemical Co.,Ltd

Strong R&D strength and team We have a R&D team with around 30 R&D personnel.All of our employees have chemical backgrounds and have worked in the chemical industry for many years.Our laboratory can synthesize target products with wei

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Raymon Biotech Co., Ltd.

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-Appearance:Off white to slight yellow solid Storage:Store in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical res

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

111992-18-8

Cas:111992-18-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

roberts ltd

2-(5-amino-2,4-Dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one 111992-18-8 b… Storage:as prescribe by the manufacturer Package:pack as requested

3H-1,2,4-Triazol-3-one, 2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-

Cas:111992-18-8

Min.Order:50 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichloro-5-nitrophenyl)-1,2,4-triazole-5(1H)-one

4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichloro-5-nitrophenyl)-1,2,4-triazole-5(1H)-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
With iron; ammonium chloride In ethanol; water for 4h; Reflux;94%
With palladium on activated charcoal; hydrogen In methanol at 50 - 60℃; under 3000.3 - 3750.38 Torr; Autoclave;94.5%
With iron; ammonium chloride In ethanol; water Reflux;
With palladium on activated charcoal; hydrogen In methanol at 60℃; under 3750.38 Torr; for 2h;31.9 g
With iron; acetic acid In water at 25 - 35℃; for 2h;2 g
2-(5-azido-2,4-dichlorobenzene)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

2-(5-azido-2,4-dichlorobenzene)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In methanol under 760.051 Torr; for 10h; Reagent/catalyst; Solvent; Pressure;92%
2,4-Dichloroaniline
554-00-7

2,4-Dichloroaniline

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hydrogenchloride; sodium nitrite / water / 1.5 h / -9 - 0 °C / Inert atmosphere
1.2: -9 - 20 °C / Inert atmosphere
1.3: 0.58 h / Inert atmosphere
2.1: triethylamine; diphenyl phosphoryl azide / toluene / 2 h / Reflux
3.1: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / Reflux
4.1: sulfuric acid; nitric acid / 25 °C
5.1: ammonium chloride; iron / water; ethanol / 4 h / Reflux
View Scheme
4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazol-5(1H)-one
79604-49-2

4,5-dihydro-1-(2,4-dichlorophenyl)-3-methyl-1,2,4-triazol-5(1H)-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / Reflux
2: sulfuric acid; nitric acid / 25 °C
3: ammonium chloride; iron / water; ethanol / 4 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / 18 h / 0 - 20 °C
2: nitric acid; sulfuric acid / 0.5 h / 25 °C
3: acetic acid; iron / water / 2 h / 25 - 35 °C
View Scheme
4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichlorophenyl)-1,2,4-triazol-5(1H)-one

4,5-dihydro-3-methyl-4-difluoromethyl-1-(2,4-dichlorophenyl)-1,2,4-triazol-5(1H)-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid; nitric acid / 25 °C
2: ammonium chloride; iron / water; ethanol / 4 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: fuming sulphuric acid; nitric acid / 40 - 50 °C
2: palladium on activated charcoal; hydrogen / methanol / 50 - 60 °C / 3000.3 - 3750.38 Torr / Autoclave
View Scheme
Multi-step reaction with 2 steps
1: fuming sulphuric acid; nitric acid / 2 h / 50 °C
2: palladium on activated charcoal; hydrogen / methanol / 2 h / 60 °C / 3750.38 Torr
View Scheme
Multi-step reaction with 2 steps
1: nitric acid; sulfuric acid / 0.5 h / 25 °C
2: acetic acid; iron / water / 2 h / 25 - 35 °C
View Scheme
Multi-step reaction with 3 steps
1: iodine; fuming sulphuric acid / 10 h / 20 °C / Cooling with ice
2: sodium azide; copper(l) iodide; L-valine; sodium hydroxide / dimethyl sulfoxide / 60 °C / Inert atmosphere
3: 5%-palladium/activated carbon; hydrogen / methanol / 10 h / 760.05 Torr
View Scheme
2-(2-(2,4-dichlorophenyl)hydrazono)propanoic acid
103998-84-1

2-(2-(2,4-dichlorophenyl)hydrazono)propanoic acid

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: triethylamine; diphenyl phosphoryl azide / toluene / 2 h / Reflux
2: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / Reflux
3: sulfuric acid; nitric acid / 25 °C
4: ammonium chloride; iron / water; ethanol / 4 h / Reflux
View Scheme
Multi-step reaction with 4 steps
1: triethylamine / toluene / 2 h / Reflux
2: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / 18 h / 0 - 20 °C
3: nitric acid; sulfuric acid / 0.5 h / 25 °C
4: acetic acid; iron / water / 2 h / 25 - 35 °C
View Scheme
1-o-chlorophenyl-3-methyl-4-difluoromethyl-1,2,4-triazol-5-one

1-o-chlorophenyl-3-methyl-4-difluoromethyl-1,2,4-triazol-5-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: antimony(III) chloride; iron(III) chloride; silica gel; chlorine / 8 - 10 °C
2: fuming sulphuric acid; nitric acid / 40 - 50 °C
3: palladium on activated charcoal; hydrogen / methanol / 50 - 60 °C / 3000.3 - 3750.38 Torr / Autoclave
View Scheme
1-(2-chlorophenyl)-3-methyl-1,2,4-triazolin-5-one
109913-40-8

1-(2-chlorophenyl)-3-methyl-1,2,4-triazolin-5-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium hydroxide; tetrabutylammomium bromide / tetrahydrofuran / 75 - 85 °C
2: antimony(III) chloride; iron(III) chloride; silica gel; chlorine / 8 - 10 °C
3: fuming sulphuric acid; nitric acid / 40 - 50 °C
4: palladium on activated charcoal; hydrogen / methanol / 50 - 60 °C / 3000.3 - 3750.38 Torr / Autoclave
View Scheme
1-phenyl-3-methyl-1H-1,2,4-triazol-5-one
22863-24-7

1-phenyl-3-methyl-1H-1,2,4-triazol-5-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: toluene; water / 110 °C
2: potassium carbonate; tetrabutylammomium bromide / 1 h / 120 °C
3: chlorine / N,N-dimethyl-formamide / 1 h / 5 - 8 °C
4: fuming sulphuric acid; nitric acid / 2 h / 50 °C
5: palladium on activated charcoal; hydrogen / methanol / 2 h / 60 °C / 3750.38 Torr
View Scheme
1-phenyl-3-methyl-1,2,4-triazol-5-one tetrabutylammonium

1-phenyl-3-methyl-1,2,4-triazol-5-one tetrabutylammonium

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium carbonate; tetrabutylammomium bromide / 1 h / 120 °C
2: chlorine / N,N-dimethyl-formamide / 1 h / 5 - 8 °C
3: fuming sulphuric acid; nitric acid / 2 h / 50 °C
4: palladium on activated charcoal; hydrogen / methanol / 2 h / 60 °C / 3750.38 Torr
View Scheme
4-difluoromethyl-4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-1,2,4-triazole

4-difluoromethyl-4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-1,2,4-triazole

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: chlorine / N,N-dimethyl-formamide / 1 h / 5 - 8 °C
2: fuming sulphuric acid; nitric acid / 2 h / 50 °C
3: palladium on activated charcoal; hydrogen / methanol / 2 h / 60 °C / 3750.38 Torr
View Scheme
2-(2,4-dichloro-5-bromophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

2-(2,4-dichloro-5-bromophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one
111992-18-8

2-(5-amino-2,4-dichlorophenyl)-4-(difluoromethyl)-2,4-dihydro-5-methyl-3H-1,2,4-triazol-3-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: magnesium; iodine / tetrahydrofuran / 1.33 h / 37 - 45 °C / Inert atmosphere
1.2: 2 h / -10 - 20 °C
2.1: sodium azide; copper(II) sulfate / methanol / 6 h / 20 °C
3.1: 5%-palladium/activated carbon; hydrogen / methanol / 10 h / 760.05 Torr
View Scheme

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