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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

N-Boc-N,N-bis(2-chloroethyl)amine Manufacturer/High quality/Best price/In stock

Cas:118753-70-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 118753-70-1 Carbamic acid,N,N-bis(2-chloroethyl)-, 1,1-dimethylethyl ester

Cas:118753-70-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

N-Boc-N,N-bis(2-chloroethyl)amine CAS NO.118753-70-1

Cas:118753-70-1

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

N-tert-Butoxycarbonyl-N,N-bis-(2-chloroethyl)-amine

Cas:118753-70-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Now we would like to update our product list for you, kindly check the below information: 1. Catalyst series ( such as Noble Metal Catalyst, Phosphorous ligand, etc ) 2. Pharmaceutical Intermediate ( such as diabtes series, Anti

118753-70-1

Cas:118753-70-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

N-Boc-N,N-bis(2-chloroethyl)amine CAS 118753-70-1

Cas:118753-70-1

Min.Order:1 Gram

FOB Price: $6.0 / 9.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 118753-70-1 with competitive price

Cas:118753-70-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

N-Boc-N,N-Bis(2-Chloroethyl)Amine 118753-70-1

Cas:118753-70-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

tert-Butyl bis(2-chloroethyl)carbamate CAS118753-70-1

Cas:118753-70-1

Min.Order:1 Kilogram

FOB Price: $7.0 / 9.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Carbamic acid,N,N-bis(2-chloroethyl)-, 1,1-dimethylethyl ester 118753-70-1

Cas:118753-70-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

N-Boc-N,N-bis(2-chloroethyl)amine CAS:118753-70-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high qualit

N-Boc-N,N-bis(2-chloroethyl)amine CAS:118753-70-1

Cas:118753-70-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Carbamic acid,N,N-bis(2-chloroethyl)-, 1,1-dimethylethyl ester

Cas:118753-70-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:118753-70-1

Cas:118753-70-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures

tert-Butyl bis(2-chloroethyl)carbamate

Cas:118753-70-1

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

N-Boc-N,N-Bis(2-Chloroethyl)Amine

Cas:118753-70-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

tert-butyl N,N-bis(2-chloroethyl)carbamate

Cas:118753-70-1

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Carbamic acid,N,N-bis(2-chloroethyl)-, 1,1-dimethylethyl ester

Cas:118753-70-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products N-Boc-N,N-Bis(2-Chloroethyl)Amine

Cas:118753-70-1

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

N-Boc-N,N-bis(2-chloroethyl)amine

Cas:118753-70-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

N-Boc-N,N-Bis(2-Chloroethyl)Amine

Cas:118753-70-1

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualified

N-Boc-N,N-bis(2-chloroethyl)amine

Cas:118753-70-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

N-Boc-N,N-bis(2-chloroethyl)amine

Cas:118753-70-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Factory SellsN-Boc-N,N-bis(2-chloroethyl)amine

Cas:118753-70-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Product Name:N-Boc-N,N-bis(2-chloroethyl)amine CAS

N-Boc-N,N-bis(2-chloroethyl)amine

Cas:118753-70-1

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

N-Boc-N,N-bis(2-chloroethyl)amine

Cas:118753-70-1

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Hot sale 99% purity N-Boc-N,N-bis(2-chloroethyl)amine CAS NO.118753-70-1

Cas:118753-70-1

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

tert-Butyl N,N-bis(2-chloroethyl)carbamate

Cas:118753-70-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

N-Boc-N,N-Bis(2-Chloroethyl)Amine

Cas:118753-70-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Hot sale 99% purity N-Boc-N,N-bis(2-chloroethyl)amine CAS NO.118753-70-1

Cas:118753-70-1

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Product name: n-Bis (2-chloroethyl) tert-butyl carbamate. Synonyms:TERT-BUTYLBIS(2-CHLOROETHYL)CARBAMATE;bis(2-chloroethyl)-carbamicacidtert-butylester;N-Boc-N,N-bis(2-chloroethyl)amine,95%;Bis(2-chloroethyl)-N-(tert-butoxycarbonyl)aMine;Bis(2-ch

n-Bis (2-chloroethyl) tert-butyl carbamate

Cas:118753-70-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

bis-(2-chloroethyl)amine hydrochloride
821-48-7

bis-(2-chloroethyl)amine hydrochloride

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

Conditions
ConditionsYield
With triethylamine100%
In dichloromethane100%
With sodium hydroxide In dichloromethane at 20℃; for 18.5h;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N,N-bis(chloro-2-ethyl)amine
334-22-5

N,N-bis(chloro-2-ethyl)amine

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;49%
With triethylamine In dichloromethane at 0 - 20℃;49%
With N-ethyl-N,N-diisopropylamine In dichloromethane
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

bis-(2-chloroethyl)amine hydrochloride
821-48-7

bis-(2-chloroethyl)amine hydrochloride

A

4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
473735-52-3

4-aminomethyl-4-(4-iodo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester

B

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

Conditions
ConditionsYield
With triethanolamine In dichloromethaneA 42%
B n/a
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N,N-bis(chloro-2-ethyl)amine
334-22-5

N,N-bis(chloro-2-ethyl)amine

A

N-(2,2'-bischloro)-diethyl-N-(1,1-dimethylethoxy)carbonyl amine

N-(2,2'-bischloro)-diethyl-N-(1,1-dimethylethoxy)carbonyl amine

B

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dichloromethane
With N-ethyl-N,N-diisopropylamine In dichloromethane
With N-ethyl-N,N-diisopropylamine In dichloromethane
bis-(2-chloroethyl)amine hydrochloride
821-48-7

bis-(2-chloroethyl)amine hydrochloride

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

N,N-bis(chloro-2-ethyl)amine
334-22-5

N,N-bis(chloro-2-ethyl)amine

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

2-(4-chloro-2-fluoro-phenyl)acetonitrile
75279-53-7

2-(4-chloro-2-fluoro-phenyl)acetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate
1093956-69-4

1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

Conditions
ConditionsYield
With sodium hydroxide; methyl tributylammonium chloride In water; toluene at 40℃; for 14h; Product distribution / selectivity;100%
Stage #1: 2-(4-chloro-2-fluoro-phenyl)acetonitrile With sodium hydride In dimethyl sulfoxide at 20℃; for 1h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 20℃; for 3h;
38%
Stage #1: 2-(4-chloro-2-fluoro-phenyl)acetonitrile With sodium hydride In dimethyl sulfoxide at 23℃; for 0.166667h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 85℃; for 1.5h;
38%
Stage #1: 2-(4-chloro-2-fluoro-phenyl)acetonitrile With sodium hydride In dimethyl sulfoxide at 23℃; for 0.166667h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 85℃; for 1.5h;
38%
With sodium hydride In dimethyl sulfoxide
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

1-t-Butoxycarbonylpiperazine
57260-71-6

1-t-Butoxycarbonylpiperazine

Conditions
ConditionsYield
With ammonium hydroxide at 60℃; for 5.5h; Time;94.3%
4-amino-phenol
123-30-8

4-amino-phenol

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

tert-butyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate
158985-25-2

tert-butyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 20h;93%
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

potassium thioacetate
10387-40-3

potassium thioacetate

N-tert-butoxycarbonyl bis(2-thioacetoxyethyl)amine
321658-86-0

N-tert-butoxycarbonyl bis(2-thioacetoxyethyl)amine

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 48h;89.8%
In N,N-dimethyl-formamide at 20℃; for 72h;82%
In N,N-dimethyl-formamide at 20℃; for 48h;35%
(2-benzyloxyphenyl)acetonitrile
92552-22-2

(2-benzyloxyphenyl)acetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

C19H20N2O

C19H20N2O

Conditions
ConditionsYield
Stage #1: (2-benzyloxyphenyl)acetonitrile With sodium hydride In Pionier 2076; N,N-dimethyl-formamide at 0 - 23℃; for 0.166667h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In Pionier 2076; N,N-dimethyl-formamide at 0 - 80℃;
Stage #3: With ammonium chloride In Pionier 2076; water; N,N-dimethyl-formamide
74%
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

p-chlorobenzyl cyanide
140-53-4

p-chlorobenzyl cyanide

4-(4-chloro-phenyl)-4-cyano-piperidine-1-carboxylic acid tert-butyl ester
218451-34-4

4-(4-chloro-phenyl)-4-cyano-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 60℃; Inert atmosphere;71%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 60℃; Inert atmosphere;71%
With sodium hydride In N,N-dimethyl-formamide at 20 - 65℃;70%
3-chloro-benzeneacetonitrile
1529-41-5

3-chloro-benzeneacetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

tert-butyl 4-(3-chlorophenyl)-4-cyanopiperidine-1-carboxylate
553631-33-7

tert-butyl 4-(3-chlorophenyl)-4-cyanopiperidine-1-carboxylate

Conditions
ConditionsYield
With 18-crown-6 ether; potassium tert-butylate In toluene for 12h; Reflux;70%
With sodium hydride In tetrahydrofuran; dimethyl sulfoxide at 20 - 60℃;
pyridin-4-yl-acetic acid ethyl ester
54401-85-3

pyridin-4-yl-acetic acid ethyl ester

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

1-tert-butyl 4-ethyl 4-(pyridin-4-yl)piperidine-1,4-dicarboxylate
954125-18-9

1-tert-butyl 4-ethyl 4-(pyridin-4-yl)piperidine-1,4-dicarboxylate

Conditions
ConditionsYield
With 18-crown-6 ether; sodium hydride In N,N-dimethyl-formamide at 25℃; for 4h;67%
2-(2,6-difluoro-4-methoxyphenyl)acetonitrile
886499-03-2

2-(2,6-difluoro-4-methoxyphenyl)acetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

1-(tert-butyloxycarbonyl)-4-(2,6-difluoro-4-methoxyphenyl)piperidine-4-carbonitrile

1-(tert-butyloxycarbonyl)-4-(2,6-difluoro-4-methoxyphenyl)piperidine-4-carbonitrile

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; paraffin oil at 0 - 80℃; for 3h;66%
With sodium hydride In N,N-dimethyl-formamide at 80℃; for 3h;881.4 mg
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

1-indene
95-13-6

1-indene

1'-(tert-butyloxycarbonyl)spiro<1H-indene-1,4'-piperidine>
137419-24-0

1'-(tert-butyloxycarbonyl)spiro<1H-indene-1,4'-piperidine>

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at 0℃;65%
With lithium hexamethyldisilazane; hydrazine In tetrahydrofuran at 2℃; for 2.5h; Cooling with ice;58%
Stage #1: 1-indene With lithium hexamethyldisilazane In tetrahydrofuran at 20℃; for 1h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In tetrahydrofuran at 0 - 20℃; for 2.5h;
57%
C26H36O4Si
1197860-92-6

C26H36O4Si

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

C35H51NO6Si
1197860-97-1

C35H51NO6Si

Conditions
ConditionsYield
Stage #1: C26H36O4Si With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In tetrahydrofuran at -78 - 0℃; for 8h; regioselective reaction;
65%
C16H21NO3
1292306-61-6

C16H21NO3

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

C25H36N2O5
1292306-62-7

C25H36N2O5

Conditions
ConditionsYield
With sodium hydride In Pionier 2076; N,N-dimethyl-formamide at 0 - 75℃; for 5h;65%
2,6-bis(mercaptomethyl)pyridine
13671-28-8

2,6-bis(mercaptomethyl)pyridine

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

N-t-butoxycarbonyl 2,8-dithia-5-aza-2,6-pyridinophane
771500-96-0

N-t-butoxycarbonyl 2,8-dithia-5-aza-2,6-pyridinophane

Conditions
ConditionsYield
Stage #1: 2,6-bis(mercaptomethyl)pyridine; N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine With CsCO3 In N,N-dimethyl-formamide at 55℃; for 24h;
Stage #2: In N,N-dimethyl-formamide at 20℃; for 20h; Further stages.;
64%
(3-bromophenyl)acetonitrile
31938-07-5

(3-bromophenyl)acetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

tert-butyl 4-(3-bromophenyl)-4-cyanopiperidine-1-carboxylate
849928-28-5

tert-butyl 4-(3-bromophenyl)-4-cyanopiperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 60℃; for 17h;63%
With sodium hydride In N,N-dimethyl-formamide at 0 - 60℃; for 3h; Inert atmosphere;
2-(2-chloropyridin-3-yl)acetonitrile
101012-32-2

2-(2-chloropyridin-3-yl)acetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

2-chloro-4'-cyano-3',4',5',6'-tetrahydro-2'H-[3,4']-bipyridinyl-1'-carboxylic acid tert-butyl ester
1315335-16-0

2-chloro-4'-cyano-3',4',5',6'-tetrahydro-2'H-[3,4']-bipyridinyl-1'-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 2-(2-chloropyridin-3-yl)acetonitrile With sodium hydride In dimethyl sulfoxide at 20℃; for 1h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 70℃; for 2h;
61%
Stage #1: 2-(2-chloropyridin-3-yl)acetonitrile With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.166667h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In N,N-dimethyl-formamide at 0 - 20℃; for 5.16h;
16.5 g
2,7-dibromo-9H-fluorene
16433-88-8

2,7-dibromo-9H-fluorene

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

tert-butyl 2,7-dibromospiro[fluorene-9,4'-piperidine]-1'-carboxylate
1616113-98-4

tert-butyl 2,7-dibromospiro[fluorene-9,4'-piperidine]-1'-carboxylate

Conditions
ConditionsYield
Stage #1: 2,7-dibromo-9H-fluorene With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In tetrahydrofuran; mineral oil at 0℃; for 4h; Reflux;
61%
p-methoxybenzylnitrile
104-47-2

p-methoxybenzylnitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

tert-butyl 4-cyano-4-(4-methoxyphenyl)piperidine-1-carboxylate
553631-38-2

tert-butyl 4-cyano-4-(4-methoxyphenyl)piperidine-1-carboxylate

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 60℃; for 17h;61%
4-fluorophenylacetonitrile
459-22-3

4-fluorophenylacetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

4-(4-fluorophenyl)-tert-butoxycarbonylpiperidine-4-carbonitrile
256951-79-8

4-(4-fluorophenyl)-tert-butoxycarbonylpiperidine-4-carbonitrile

Conditions
ConditionsYield
Stage #1: 4-fluorophenylacetonitrile With sodium hydride In dimethyl sulfoxide at 20℃; for 1.5h;
Stage #2: N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine In dimethyl sulfoxide at 20℃; for 2h;
60%
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 60℃; for 16h;58%
With sodium hydride In N,N-dimethyl-formamide at 0 - 60℃; for 24h;54%
2-(2-(benzyloxy)-5-bromophenyl)acetonitrile

2-(2-(benzyloxy)-5-bromophenyl)acetonitrile

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine
118753-70-1

N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

4-(2-benzyloxy-5-bromophenyl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester
1295645-05-4

4-(2-benzyloxy-5-bromophenyl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 60℃; for 18h;60%

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