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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

N-[4-[[4-(Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N'-[4-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]phenyl]urea

Cas:1197160-78-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% PF-05212384 1197160-78-3 GMP Manufacturer

Cas:1197160-78-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

TIANFUCHEM-- 1197160-78-3--High purity PF-05212384 in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business

TIANFUCHEM-- 1197160-78-3--High purity PF-05212384 in stock

Cas:1197160-78-3

Min.Order:1 Metric Ton

FOB Price: $2000.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 1197160-78-3 with competitive price

Cas:1197160-78-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

PKI-587

Cas:1197160-78-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

PKI-587

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

PKI-587 Gedatolisib 1197160-78-3

Cas:1197160-78-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

PKI-587

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferPF-05212384

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/PF-05212384 (PKI-587)/SAGECHEM/Manufacturer in China

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

PF-05212384

Cas:1197160-78-3

Min.Order:1 Kilogram

Negotiable

Type:Other

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Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

PKI-587

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

PF-05212384

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

PKI-587

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Gedatolisib (PF-05212384, PKI-587) Application:Gedatolisib (PF-05212384, PKI-587)

Gedatolisib (PF-05212384, PKI-587)

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

PF-05212384 (PKI-587) CAS No.1197160-78-3

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

PF-05212384

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

PF-05212384

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

1197160-78-3

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

N-[4-[[4-(Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N'-[4-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]phenyl]urea cas 1197160-78-3Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:int

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

PF-05212384

Cas:1197160-78-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

dimethyl-piperidin-4-yl-amine
50533-97-6

dimethyl-piperidin-4-yl-amine

4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid
1197160-66-9

4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid

PKI-587
1197160-78-3

PKI-587

Conditions
ConditionsYield
Stage #1: 4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 50℃; for 2h;
Stage #2: dimethyl-piperidin-4-yl-amine In tetrahydrofuran at 53℃; for 16h; Product distribution / selectivity;
88%
Stage #1: 4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 20℃;
Stage #2: dimethyl-piperidin-4-yl-amine In 1-methyl-pyrrolidin-2-one at 20℃;
52%
(4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone
50534-08-2

(4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone

phenyl (4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)carbamate

phenyl (4-(4,6-dimorpholino-1,3,5-triazin-2-yl)phenyl)carbamate

PKI-587
1197160-78-3

PKI-587

Conditions
ConditionsYield
In dimethyl sulfoxide at 65℃; for 3h; Green chemistry;88%
In N,N-dimethyl-formamide at 90℃; for 12h;16.3%
(4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone
50534-08-2

(4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone

4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline
1197159-91-3

4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline

phenyl chloroformate
1885-14-9

phenyl chloroformate

PKI-587
1197160-78-3

PKI-587

Conditions
ConditionsYield
Stage #1: 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline; phenyl chloroformate With pyridine In N,N-dimethyl-formamide at 5 - 20℃;
Stage #2: (4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone In N,N-dimethyl-formamide at 90℃; for 12h;
17.8%
4-nitrobenzonitrile
619-72-7

4-nitrobenzonitrile

PKI-587
1197160-78-3

PKI-587

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium hydroxide / ethanol / 3 h / 78 °C / Green chemistry
2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 65 °C / Inert atmosphere; Green chemistry
3.1: hydrogen / tetrahydrofuran / 12 h / 20 °C / Green chemistry
4.1: pyridine / dichloromethane / 5 °C / Green chemistry
4.2: 2 h / 5 °C / Green chemistry
5.1: dimethyl sulfoxide / 3 h / 65 °C / Green chemistry
View Scheme
Multi-step reaction with 4 steps
1.1: potassium hydroxide / 2-methoxy-ethanol / 4 h / 90 °C
2.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere
2.2: 4.5 h / Inert atmosphere
3.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C
4.1: pyridine / N,N-dimethyl-formamide / 5 - 20 °C
4.2: 12 h / 90 °C
View Scheme
Multi-step reaction with 5 steps
1.1: potassium hydroxide / 2-methoxy-ethanol / 4 h / 90 °C
2.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere
2.2: 4.5 h / Inert atmosphere
3.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C
4.1: pyridine / N,N-dimethyl-formamide / 2 h / 5 - 20 °C
5.1: N,N-dimethyl-formamide / 12 h / 90 °C
View Scheme
2,4-diamino-6-(4-nitrophenyl)-1,3,5-triazine
29366-73-2

2,4-diamino-6-(4-nitrophenyl)-1,3,5-triazine

PKI-587
1197160-78-3

PKI-587

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 65 °C / Inert atmosphere; Green chemistry
2.1: hydrogen / tetrahydrofuran / 12 h / 20 °C / Green chemistry
3.1: pyridine / dichloromethane / 5 °C / Green chemistry
3.2: 2 h / 5 °C / Green chemistry
4.1: dimethyl sulfoxide / 3 h / 65 °C / Green chemistry
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere
1.2: 4.5 h / Inert atmosphere
2.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C
3.1: pyridine / N,N-dimethyl-formamide / 5 - 20 °C
3.2: 12 h / 90 °C
View Scheme
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere
1.2: 4.5 h / Inert atmosphere
2.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C
3.1: pyridine / N,N-dimethyl-formamide / 2 h / 5 - 20 °C
4.1: N,N-dimethyl-formamide / 12 h / 90 °C
View Scheme
4,4'-(6-(4-nitrophenyl)-1,3,5-triazine-2,4-diyl)dimorpholine

4,4'-(6-(4-nitrophenyl)-1,3,5-triazine-2,4-diyl)dimorpholine

PKI-587
1197160-78-3

PKI-587

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: hydrogen / tetrahydrofuran / 12 h / 20 °C / Green chemistry
2.1: pyridine / dichloromethane / 5 °C / Green chemistry
2.2: 2 h / 5 °C / Green chemistry
3.1: dimethyl sulfoxide / 3 h / 65 °C / Green chemistry
View Scheme
Multi-step reaction with 2 steps
1.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C
2.1: pyridine / N,N-dimethyl-formamide / 5 - 20 °C
2.2: 12 h / 90 °C
View Scheme
Multi-step reaction with 3 steps
1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C
2: pyridine / N,N-dimethyl-formamide / 2 h / 5 - 20 °C
3: N,N-dimethyl-formamide / 12 h / 90 °C
View Scheme
L-Lactic acid
79-33-4

L-Lactic acid

PKI-587
1197160-78-3

PKI-587

1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea L-lactate

1-(4-((4-(dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea L-lactate

Conditions
ConditionsYield
In ethyl acetate; N,N-dimethyl-formamide at 23℃; for 24h; Temperature;

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