As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:1197160-78-3
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryTIANFUCHEM-- 1197160-78-3--High purity PF-05212384 in stock Our company was built in 2009 with an ISO certificate.In the past 10 years, we have grown up as a famous fine chemicals supplier in China And we had established stable business
Cas:1197160-78-3
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:1197160-78-3
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:1197160-78-3
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inquiryOur company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:1197160-78-3
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inquiryOur Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:1197160-78-3
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FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:1197160-78-3
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:1197160-78-3
Min.Order:1 Metric Ton
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inquirySAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe
Cas:1197160-78-3
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inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:1197160-78-3
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inquiryhigh purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
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inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for
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inquiryGedatolisib (PF-05212384, PKI-587) Application:Gedatolisib (PF-05212384, PKI-587)
Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
Cas:1197160-78-3
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inquiryWe are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use
Supply top quality products with a reasonable price Application:api
N-[4-[[4-(Dimethylamino)-1-piperidinyl]carbonyl]phenyl]-N'-[4-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]phenyl]urea cas 1197160-78-3Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:int
Cas:1197160-78-3
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
dimethyl-piperidin-4-yl-amine
4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid
PKI-587
Conditions | Yield |
---|---|
Stage #1: 4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 50℃; for 2h; Stage #2: dimethyl-piperidin-4-yl-amine In tetrahydrofuran at 53℃; for 16h; Product distribution / selectivity; | 88% |
Stage #1: 4-(3-(4-(4,6-bismorpholine-1,3,5-triazin-2-yl)phenyl)ureido)benzoic acid With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 20℃; Stage #2: dimethyl-piperidin-4-yl-amine In 1-methyl-pyrrolidin-2-one at 20℃; | 52% |
(4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone
PKI-587
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 65℃; for 3h; Green chemistry; | 88% |
In N,N-dimethyl-formamide at 90℃; for 12h; | 16.3% |
(4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone
4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline
phenyl chloroformate
PKI-587
Conditions | Yield |
---|---|
Stage #1: 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline; phenyl chloroformate With pyridine In N,N-dimethyl-formamide at 5 - 20℃; Stage #2: (4-aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone In N,N-dimethyl-formamide at 90℃; for 12h; | 17.8% |
4-nitrobenzonitrile
PKI-587
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: potassium hydroxide / ethanol / 3 h / 78 °C / Green chemistry 2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 65 °C / Inert atmosphere; Green chemistry 3.1: hydrogen / tetrahydrofuran / 12 h / 20 °C / Green chemistry 4.1: pyridine / dichloromethane / 5 °C / Green chemistry 4.2: 2 h / 5 °C / Green chemistry 5.1: dimethyl sulfoxide / 3 h / 65 °C / Green chemistry View Scheme | |
Multi-step reaction with 4 steps 1.1: potassium hydroxide / 2-methoxy-ethanol / 4 h / 90 °C 2.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere 2.2: 4.5 h / Inert atmosphere 3.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C 4.1: pyridine / N,N-dimethyl-formamide / 5 - 20 °C 4.2: 12 h / 90 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: potassium hydroxide / 2-methoxy-ethanol / 4 h / 90 °C 2.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere 2.2: 4.5 h / Inert atmosphere 3.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C 4.1: pyridine / N,N-dimethyl-formamide / 2 h / 5 - 20 °C 5.1: N,N-dimethyl-formamide / 12 h / 90 °C View Scheme |
2,4-diamino-6-(4-nitrophenyl)-1,3,5-triazine
PKI-587
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 65 °C / Inert atmosphere; Green chemistry 2.1: hydrogen / tetrahydrofuran / 12 h / 20 °C / Green chemistry 3.1: pyridine / dichloromethane / 5 °C / Green chemistry 3.2: 2 h / 5 °C / Green chemistry 4.1: dimethyl sulfoxide / 3 h / 65 °C / Green chemistry View Scheme | |
Multi-step reaction with 3 steps 1.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere 1.2: 4.5 h / Inert atmosphere 2.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C 3.1: pyridine / N,N-dimethyl-formamide / 5 - 20 °C 3.2: 12 h / 90 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydride / N,N-dimethyl acetamide / 0.17 h / 55 - 60 °C / Inert atmosphere 1.2: 4.5 h / Inert atmosphere 2.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C 3.1: pyridine / N,N-dimethyl-formamide / 2 h / 5 - 20 °C 4.1: N,N-dimethyl-formamide / 12 h / 90 °C View Scheme |
PKI-587
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogen / tetrahydrofuran / 12 h / 20 °C / Green chemistry 2.1: pyridine / dichloromethane / 5 °C / Green chemistry 2.2: 2 h / 5 °C / Green chemistry 3.1: dimethyl sulfoxide / 3 h / 65 °C / Green chemistry View Scheme | |
Multi-step reaction with 2 steps 1.1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C 2.1: pyridine / N,N-dimethyl-formamide / 5 - 20 °C 2.2: 12 h / 90 °C View Scheme | |
Multi-step reaction with 3 steps 1: nickel; hydrogen / tetrahydrofuran / 20 h / 20 °C 2: pyridine / N,N-dimethyl-formamide / 2 h / 5 - 20 °C 3: N,N-dimethyl-formamide / 12 h / 90 °C View Scheme |
L-Lactic acid
PKI-587
Conditions | Yield |
---|---|
In ethyl acetate; N,N-dimethyl-formamide at 23℃; for 24h; Temperature; |
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