CAS No.134628-42-5,PIPERAZINE-2,2,3,3,5,5,6,6-D8 Suppliers

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

PIPERAZINE-2,2,3,3,5,5,6,6-D8

Cas:134628-42-5

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

PIPERAZINE-2,2,3,3,5,5,6,6-D8

Cas:134628-42-5

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Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

Piperazine-2,2,3,3,5,5,6,6-d8

Cas:134628-42-5

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

PIPERAZINE-2,2,3,3,5,5,6,6-D8

Cas:134628-42-5

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Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

PIPERAZINE-2,2,3,3,5,5,6,6-D8

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Antimex Chemical Limied

factory?direct?sale Application:healing drugs

PIPERAZINE-2,2,3,3,5,5,6,6-D8

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

PIPERAZINE-2,2,3,3,5,5,6,6-D8

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Simson Pharma Limited

The system can just identify the products information in first sheet, it is not be permitted to add or edit new sheet by userself.Our products are required in MG to Gram only. · Pharmaceutical Reference Standards· Traceable workin

Piperazine D8

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Synthetic route

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1054624-86-0
2-chloro-N-(2,6-di(d3-methyl)phenyl)-2,2-d2-acetamide

: 1054624-87-1
N-(2,6-di(d3-methyl)phenyl)-2-(d8-piperazin-1-yl)-2,2-d2-acetamide

Conditions

Conditions	Yield
Stage #1: piperazine-2,2,3,3,5,5,6,6-d8; 2-chloro-N-(2,6-di(d3-methyl)phenyl)-2,2-d2-acetamide In ethyl [2]alcohol for 3h; Heating / reflux; Stage #2: With ammonia In ethyl [2]alcohol; water	99%

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 100-00-5
4-chlorobenzonitrile

: C10H5(2)H8N3O2

Conditions

Conditions	Yield
In diethylene glycol dimethyl ether at 100℃; for 6h;	80%

: 942271-60-5
tert-butyl 4-fluoro-2-nitrobenzoate

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: C15H13(2)H8N3O4

Conditions

Conditions	Yield
In water; N,N-dimethyl-formamide at 20℃; for 5h;	74.5%

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1613192-04-3
1-[3-[(2-amino-6-fluoro-pyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]-5-fluoro-4-pyridyl]piperidine-4-carboxylic acid hydrochloride

: 2-amino-6-fluoro-N-(5-fluoro-4-(4-(2,2,3,3,5,5,6,6-octadeutero-piperazine-1-carbonyl)piperidin-1-yl)-3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 20℃; for 18h;	48%

: 89793-12-4
ethyl 2-chloropyrimidine-5-carboxylate

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 24424-99-5
di-tert-butyl dicarbonate

: C16H16(2)H8N4O4

Conditions

Conditions	Yield
Stage #1: ethyl 2-chloropyrimidine-5-carboxylate; piperazine-2,2,3,3,5,5,6,6-d8 With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 20℃; for 3h; Cooling with ice; Inert atmosphere; Stage #2: di-tert-butyl dicarbonate In 1,4-dioxane for 1h; Inert atmosphere;	47.4%

...Expand

: 75-75-2
methanesulfonic acid

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 4-(chloromethyl-d2)-N-(4-(methyl-d3)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide

: N-(4-(methyl-d3)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-((piperazin-1-yl-d8)methyl-d2)benzamide bis-methanesulfonic acid salt

Conditions

Conditions	Yield
Stage #1: piperazine-2,2,3,3,5,5,6,6-d8; 4-(chloromethyl-d2)-N-(4-(methyl-d3)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide In dichloromethane; acetonitrile Reflux; Stage #2: With [D]-sodium hydroxide In methanol; chloroform; water-d2 Stage #3: methanesulfonic acid In dichloromethane	43%

...Expand

: 75-75-2
methanesulfonic acid

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1207619-83-7
4-(chloromethyl-d2)-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide

: N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-((piperazin-1-yl-d8)methyl-d2)benzamide bis-methanesulfonic acid salt

Conditions

Conditions	Yield
Stage #1: piperazine-2,2,3,3,5,5,6,6-d8; 4-(chloromethyl-d2)-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide In dichloromethane; acetonitrile Reflux; Stage #2: With [D]-sodium hydroxide In methanol; chloroform; water-d2 Stage #3: methanesulfonic acid In acetone	33%

...Expand

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 134-83-8
1-chloro-4-(chloro(phenyl)methyl)benzene

: 1-[(4-chlorophenyl)phenylmethyl]piperazine-2,2,3,3,5,5,6,6-d8

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 85℃; Sealed tube;	32.1%

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1-(3-[D3]methoxy-4-nitrophenyl)piperidin-4-one

: C16H13(2)H11N4O3

Conditions

Conditions	Yield
With titanium(IV) isopropylate at 20℃;	25.4%

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1006717-19-6
d8-furan-2-yl-piperazin-1-yl-methanone

Conditions

Conditions	Yield
Stage #1: 2-furanoic acid With N-Bromosuccinimide; triphenylphosphine In dichloromethane at 0℃; for 0.25h; Stage #2: piperazine-2,2,3,3,5,5,6,6-d8 With pyridine In dichloromethane at 20℃;

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1092805-03-2
d12-2-(2-methoxyphenoxymethyl)oxirane

: 1092805-04-3
d20-1-(2-methoxy-phenoxy)-3-piperazin-1-yl-propan-2-ol

Conditions

Conditions	Yield
In methanol at 0 - 5℃; for 3h;

: 14210-25-4
5-Chloro-1-phenyltetrazole

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1352806-46-2
C11H6(2)H8N6

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 115℃; for 72h;

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 43019-90-5
benzoyl chloride-d5

: 1352806-44-0
C11H(2)H13N2O

Conditions

Conditions	Yield
Stage #1: piperazine-2,2,3,3,5,5,6,6-d8 With n-butyllithium In tetrahydrofuran; hexane at 20℃; for 0.5h; Stage #2: benzoyl chloride-d5 In tetrahydrofuran; hexane for 0.0833333h;

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 64248-62-0
3,4-Difluorobenzonitrile

: 3-fluoro-4-(piperazin-1-yl-2,2,3,3,5,5,6,6-d8)benzonitrile

Conditions

Conditions	Yield
at 110℃; for 16h;

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 1235865-75-4
2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoic acid methyl ester

: methyl 4-[(2,2,3,3,5,5,6,6-2H8)piperazin-1-yl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate

Conditions

Conditions	Yield
In dimethyl sulfoxide at 85℃; for 2.5h;

: 134628-42-5
piperazine-2,2,3,3,5,5,6,6-d8

: 24424-99-5
di-tert-butyl dicarbonate

: 1126621-86-0
tert-butyl (2,2,3,3,5,5,6,6-(2H8))piperazine-1-carboxylate

Conditions

Conditions	Yield
Stage #1: piperazine-2,2,3,3,5,5,6,6-d8 With trifluoroacetic acid In methanol; water at 20 - 28℃; for 0.75h; Stage #2: di-tert-butyl dicarbonate With iodine In methanol; water at 20℃;	3.43 g

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Antimex Chemical Limied

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