Safety: Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. A human poison by inhalation. Poison experimentally by inhalation, intravenous, subcutaneous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects by inhalation: somnolence, fever, and other pulmonary changes. Vapors may cause coughing, dyspnea (difficult breathing), irritation, congestion and edema of the lungs, tachycardia (rapid pulse), cyanosis, headache, dizziness, and weakness. Toxicity by inhalation is believed to be caused by both the nickel and carbon monoxide liberated in the lungs. Chronic exposure may cause cancer of lungs, nasal sinuses. Sensitization dermatitis is fairly common. Probably the most hazardous compound of nickel in the workplace. A common air contaminant. It is lipid soluble and can cross biological membranes (e.g., lung alveolus, blood-brain barrier, placental barrier).A very dangerous fire hazard when exposed to heat, flame, or oxidizers. Moderate explosion hazard when exposed to heat or flame. Explodes when heated to about 60°. Explosive reaction with liquid bromine, mercury + oxygen, oxygen + butane. Violent reaction with dinitrogen tetraoxide, air, oxygen. Reacts with tetrachloropropadiene to form the extremely sensitive explosive dicarbonyl trichloropropenyl dinickel chloride dimer. Can react with oxidizing materials. To fight fire, use water, foam, CO2, dry chemical. When heated to decomposition or on contact with acid or acid fumes, it emits highly toxic fumes of carbon monoxide. See also NICKEL COMPOUNDS and CARBONYLS.
Analytical Methods: | | For occupational chemical analysis use NIOSH: Nickel Carbonyl, 6007.
Transport Information:
PSA:0.00000
LogP:-0.83200
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