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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Intermediates Transportation:by air or by sea Port:Shanghai, Qingdao

3,4-dichloro-1-fluorobenzene 1435-49-0

Cas:1435-49-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

High Quality,High Purity of 1,2-Dichloro-4-fluorobenzene from Henan Tianfu Chemical: Henan Tianfu Chemical Co.,LTD was built in 2009 with an ISO certificate in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 1435-49-0 with fast shipping

Cas:1435-49-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 1,2-Dichloro-4-fluorobenzene CAS: 1435-49-0 MF: C6H3Cl2F MW: 164.99 EINECS: 215-858-3 Mol File: 1435-49-0.mol 1,2-Dichloro-4-fluorobenzene Structure 1,2-Dichloro-4-fluorobenzene Chemical Properties Melting point

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

1,2-Dichloro-4-fluorobenzene CAS:1435-49-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality orga

1,2-Dichloro-4-fluorobenzene CAS:1435-49-0

Cas:1435-49-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

1,2-Dichloro-4-fluorobenzene CAS NO.1435-49-0

Cas:1435-49-0

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providing h

Factory Supply 3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Other

inquiry

Siwei Development Group Ltd.

Product name: 3,4-Dichloro-1-Fluorobenzene CAS No.:1435-49-0 Molecule Formula:C6H3Cl2F Molecule Weight:164.99 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TEST

High Quality 3,4-Dichloro-1-Fluorobenzene on stock

Cas:1435-49-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

1,2-dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3,4-Dichlorofluorobenzene cas no. 1435-49-0 98%

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city?in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api,?intermediat

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

1,2-Dichloro-4-fluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

1,2-Dichloro-4-fluorobenzene cas 1435-49-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

1,2-Dichloro-4-fluorobenzene cas 1435-49-0

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Best quality with low priceAppearance:clear colorless to slightly yellow liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

3,4-Dichlorofluorobenzene

Cas:1435-49-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

potassium m, p-dichloro phenyltrifluoroborate

potassium m, p-dichloro phenyltrifluoroborate

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

Conditions
ConditionsYield
With lithium hydroxide monohydrate; silver trifluoromethanesulfonate; Selectfluor In ethyl acetate at 55℃; Sealed tube;75%
4-bromo-1,2-dichlorobenzene
18282-59-2

4-bromo-1,2-dichlorobenzene

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

Conditions
ConditionsYield
Stage #1: 4-bromo-1,2-dichlorobenzene With TurboGrignard In tetrahydrofuran; 1,4-dioxane at 0 - 25℃; Inert atmosphere;
Stage #2: With N-fluorobis(benzenesulfon)imide In dichloromethane; octadecafluorodecahydronaphthalene (cis+trans) at -78 - 20℃; Inert atmosphere;
34%
Stage #1: 4-bromo-1,2-dichlorobenzene With TurboGrignard In tetrahydrofuran at 0℃; Inert atmosphere;
Stage #2: With N-fluorobis(benzenesulfon)imide In dichloromethane; octadecafluorodecahydronaphthalene (cis+trans) at -78 - 25℃; Inert atmosphere;
34%
2-chloro-5-fluoroaniline
452-83-5

2-chloro-5-fluoroaniline

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

Conditions
ConditionsYield
Reaktion nach Sandmeyer;
m,p-dichloroaniline
95-76-1

m,p-dichloroaniline

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

Conditions
ConditionsYield
With hydrogenchloride; tetrafluoroboric acid; sodium nitrite Erhitzen des Reaktionsprodukts auf 150grad;
2,3-dichlorofluorobenzene
36556-50-0

2,3-dichlorofluorobenzene

A

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

B

3-chlorofluorobenzene
625-98-9

3-chlorofluorobenzene

C

1,4-dichloro-2-fluorobenzene
348-59-4

1,4-dichloro-2-fluorobenzene

D

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
In acetonitrile for 10h; Product distribution; Irradiation;A 5 % Chromat.
B 5 % Chromat.
C 13 % Chromat.
D 1 % Chromat.
sulfuric acid
7664-93-9

sulfuric acid

m,p-dichloroaniline
95-76-1

m,p-dichloroaniline

A

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

B

3,4-dichlorophenol
95-77-2

3,4-dichlorophenol

C

1,2-dichloro-benzene
95-50-1

1,2-dichloro-benzene

Conditions
ConditionsYield
Behandeln der Diazoloesung mit heisser Flusssaeure.Diazotization;
fluorobenzene
462-06-6

fluorobenzene

iron-powder

iron-powder

A

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

B

1-Chloro-4-fluorobenzene
352-33-0

1-Chloro-4-fluorobenzene

C

1,3-dichloro-4-fluorobenzene
1435-48-9

1,3-dichloro-4-fluorobenzene

Conditions
ConditionsYield
Einleiten von 2 Mol Chlor;
diazotized 5-fluoro-2-chloro-aniline

diazotized 5-fluoro-2-chloro-aniline

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

C18H7Cl2F4S2(1+)*BF4(1-)

C18H7Cl2F4S2(1+)*BF4(1-)

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

Conditions
ConditionsYield
With tetrakis(acetonitrile)copper(I)tetrafluoroborate; [4,4’-bis(1,1-dimethylethyl)-2,2’-bipyridine-N1,N1‘]bis [3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-N]phenyl-C]iridium(III) hexafluorophosphate; cesium fluoride In acetone at 30℃; for 20h; Inert atmosphere; Irradiation;63 %Spectr.
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2,3-Dichloro-6-fluorobenzaldehyde
95399-95-4

2,3-Dichloro-6-fluorobenzaldehyde

Conditions
ConditionsYield
Stage #1: 3,4-dichlorofluorobenzene With lithium diisopropyl amide In tetrahydrofuran at -65℃; for 0.5h; Inert atmosphere;
Stage #2: N,N-dimethyl-formamide In tetrahydrofuran at -65℃; for 0.333333h; Inert atmosphere;
94%
tetrachloromethane
56-23-5

tetrachloromethane

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

C7H2Cl5F

C7H2Cl5F

Conditions
ConditionsYield
With 1,2-bis(N-methylimidazolium)ethane chloroaluminate at 60℃; for 4h; Time;92.9%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

1-fluoro-3,4-bis(trimethylsilyl)benzene
1265682-42-5

1-fluoro-3,4-bis(trimethylsilyl)benzene

Conditions
ConditionsYield
With 1,3-dimethyl-2-imidazolidinone; magnesium; copper(l) chloride; lithium chloride at 55℃; for 17h;88%
2,2,6,6-tetramethylpiperidin-1-ol
7031-93-8

2,2,6,6-tetramethylpiperidin-1-ol

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

4-(3,4-dichloro-phenoxy)-2,2,6,6-tetramethyl-piperidine hydrochloride

4-(3,4-dichloro-phenoxy)-2,2,6,6-tetramethyl-piperidine hydrochloride

Conditions
ConditionsYield
Stage #1: 2,2,6,6-tetramethylpiperidin-1-ol; 3,4-dichlorofluorobenzene With potassium tert-butylate In tetrahydrofuran at 20℃; for 4h;
Stage #2: With hydrogenchloride In diethyl ether for 0.166667h; Product distribution / selectivity;
84%
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

3-Bromonitrobenzene
585-79-5

3-Bromonitrobenzene

2,3-dichloro-6-fluoro-3’-nitrobiphenyl
1638159-33-7

2,3-dichloro-6-fluoro-3’-nitrobiphenyl

Conditions
ConditionsYield
With PdCl(1,4-bis(diphenylphosphino)butane)(C3H5); potassium pivalate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; regioselective reaction;64%
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

1,3-Diamino-2-hydroxypropane
616-29-5

1,3-Diamino-2-hydroxypropane

2-(3,4-dichlorophenoxy)propane-1,3-diamine
676167-20-7

2-(3,4-dichlorophenoxy)propane-1,3-diamine

Conditions
ConditionsYield
Stage #1: 1,3-Diamino-2-hydroxypropane With sodium hydride In N,N-dimethyl acetamide
Stage #2: 3,4-dichlorofluorobenzene In N,N-dimethyl acetamide at 170℃; for 0.0694444h; microwave irradiation;
62%
3,5-dimethoxyphenol
500-99-2

3,5-dimethoxyphenol

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

1,2-dichloro-4-(3,5-dimethoxyphenoxy)benzene
1379803-46-9

1,2-dichloro-4-(3,5-dimethoxyphenoxy)benzene

Conditions
ConditionsYield
Stage #1: 3,5-dimethoxyphenol With caesium carbonate In 1-methyl-pyrrolidin-2-one at 50℃; for 0.5h; Inert atmosphere;
Stage #2: 3,4-dichlorofluorobenzene In 1-methyl-pyrrolidin-2-one at 120℃; for 2h; Inert atmosphere;
60%
3-Bromopyridine
626-55-1

3-Bromopyridine

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

3-(2,3-dichloro-6-fluorophenyl)pyridine
1638159-34-8

3-(2,3-dichloro-6-fluorophenyl)pyridine

Conditions
ConditionsYield
With PdCl(1,4-bis(diphenylphosphino)butane)(C3H5); potassium pivalate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; regioselective reaction;58%
2-Chloroquinoline
612-62-4

2-Chloroquinoline

3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

2-(2,3-dichloro-6-fluorophenyl)quinoline

2-(2,3-dichloro-6-fluorophenyl)quinoline

Conditions
ConditionsYield
With PdCl(1,4-bis(diphenylphosphino)butane)(C3H5); tetrabutylammomium bromide; potassium pivalate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; Green chemistry; regioselective reaction;39%
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

sodium methylate
124-41-4

sodium methylate

3,4-dichlorophenol
95-77-2

3,4-dichlorophenol

Conditions
ConditionsYield
at 180℃; nach 7 Tagen;
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

sodium methylate
124-41-4

sodium methylate

3,4-dichloroanisole
36404-30-5

3,4-dichloroanisole

Conditions
ConditionsYield
With methanol at 180℃;
at 180℃; nach 6 Stunden;
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

3,4-dichlorophenol
95-77-2

3,4-dichlorophenol

Conditions
ConditionsYield
With sodium methylate
With methanol; sodium methylate at 180℃;
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

1,2-dichloro-4-fluoro-5-nitrobenzene
2339-78-8

1,2-dichloro-4-fluoro-5-nitrobenzene

Conditions
ConditionsYield
With sulfuric acid; nitric acid
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

1,2,4-Tribromo-5,6-dichloro-3-fluoro-benzene
59410-15-0

1,2,4-Tribromo-5,6-dichloro-3-fluoro-benzene

Conditions
ConditionsYield
(i) Hg(O2CCF3)2, (ii) KBr3, aq. MeOH; Multistep reaction;
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

4,5-dichloro-2-fluorobenzenesulfonyl chloride
13656-52-5

4,5-dichloro-2-fluorobenzenesulfonyl chloride

Conditions
ConditionsYield
With chlorosulfonic acid
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

4-(hydroxyphenylmethyl)piperidine-1-carboxylic acid tert-butyl ester
269740-46-7, 269741-35-7

4-(hydroxyphenylmethyl)piperidine-1-carboxylic acid tert-butyl ester

4-[(3,4-dichloro-phenoxy)-phenyl-methyl]-piperidine-1-carboxylic acid tert-butyl ester

4-[(3,4-dichloro-phenoxy)-phenyl-methyl]-piperidine-1-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: 4-(hydroxyphenylmethyl)piperidine-1-carboxylic acid tert-butyl ester With sodium hydride In dimethyl sulfoxide at 20℃;
Stage #2: 3,4-dichlorofluorobenzene With Potassium benzoate In dimethyl sulfoxide at 65℃;
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

5-(3,4-dichlorophenoxy)-3,4,5,6-tetrahydropyrimidin-2(1H)-one

5-(3,4-dichlorophenoxy)-3,4,5,6-tetrahydropyrimidin-2(1H)-one

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: NaH / N,N-dimethyl-acetamide
1.2: 62 percent / N,N-dimethyl-acetamide / 0.07 h / 170 °C / microwave irradiation
2.1: 53 percent / ethanol / 0.06 h / 140 °C / microwave irradiation
3.1: 95 percent / acetonitrile / 0.14 h / 130 °C / microwave irradiation
4.1: 100 percent / NH4OH / H2O / 0.14 h / 150 °C / microwave irradiation
View Scheme
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

5-(3,4-dichlorophenoxy)-3,4,5,6-tetrahydropyrimidine-2(1H)-thione
676167-23-0

5-(3,4-dichlorophenoxy)-3,4,5,6-tetrahydropyrimidine-2(1H)-thione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaH / N,N-dimethyl-acetamide
1.2: 62 percent / N,N-dimethyl-acetamide / 0.07 h / 170 °C / microwave irradiation
2.1: 53 percent / ethanol / 0.06 h / 140 °C / microwave irradiation
View Scheme
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

5-(3,4-dichlorophenoxy)-2-methylsulfanyl-3,4,5,6-tetrahydropyrimidine hydroiodide

5-(3,4-dichlorophenoxy)-2-methylsulfanyl-3,4,5,6-tetrahydropyrimidine hydroiodide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: NaH / N,N-dimethyl-acetamide
1.2: 62 percent / N,N-dimethyl-acetamide / 0.07 h / 170 °C / microwave irradiation
2.1: 53 percent / ethanol / 0.06 h / 140 °C / microwave irradiation
3.1: 95 percent / acetonitrile / 0.14 h / 130 °C / microwave irradiation
View Scheme
3,4-dichlorofluorobenzene
1435-49-0

3,4-dichlorofluorobenzene

2-amino-5-(3,4-dichlorophenoxy)-3,4,5,6-tetrahydropyrimidine hydrobromide

2-amino-5-(3,4-dichlorophenoxy)-3,4,5,6-tetrahydropyrimidine hydrobromide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaH / N,N-dimethyl-acetamide
1.2: 62 percent / N,N-dimethyl-acetamide / 0.07 h / 170 °C / microwave irradiation
2.1: 53 percent / propan-2-ol / 0.17 h / 120 °C / microwave irradiation
View Scheme

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