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Qingdao Beluga Import and Export Co., LTD

(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone CAS:147254-64-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating rese

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Ranirestat

Cas:147254-64-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Ranirestat

Cas:147254-64-6

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Ranirestat CAS No.147254-64-6

Cas:147254-64-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

Raniestat

Cas:147254-64-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Ranirestat

Cas:147254-64-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Shochem(Shanghai) Co., Ltd

good quality and best price Application:R&D for pharmaceutical Port:Shanghai

Ranirestat

Cas:147254-64-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan MoonZY Biological Technology Co.,Ltd

instock with good quality and wholesale price Storage:Keep in a cool & dry place Package:Packing material and QTY as your request Application:Pharma;Industry;other application Transportation:Express or as your request Port:Any port of China

Ranirestat,147254-64-6

Cas:147254-64-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

147254-64-6

Cas:147254-64-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

coolpharm Ltd

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar

RANIRESTAT

Cas:147254-64-6

Min.Order:0

Negotiable

Type:Other

inquiry

Sparrow Chemical Co.,Ltd

Our company provides the best service for our customers. Under the premise of ensuring quality and delivery date, give customers the best price. The company is more willing to meet our customers. If you want to visit our factories and warehouses, we

Shanghai Haoyuan Chemexpress Co., Ltd.

Ranirestat

Cas:147254-64-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

(S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate
1211939-75-1

(S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; Inert atmosphere;95%
4-bromo-2-fluorobenzylamine
112734-22-2

4-bromo-2-fluorobenzylamine

R-(-)-3-ethoxycarbonyl-3-(2-(trichloroacetyl)pyrrol-1-yl)pyrrolidin-2,5-dione
159213-26-0

R-(-)-3-ethoxycarbonyl-3-(2-(trichloroacetyl)pyrrol-1-yl)pyrrolidin-2,5-dione

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 5h;71%
With triethylamine In N,N-dimethyl-formamide at 20℃;65%
With triethylamine In N,N-dimethyl-formamide at 20℃; for 8h;65%
(2R)-2-ethoxycarbonyl-2-(pyrrol-1-yl)succinimide diisopropylamine salt
1000784-39-3

(2R)-2-ethoxycarbonyl-2-(pyrrol-1-yl)succinimide diisopropylamine salt

4-bromo-2-fluorobenzylamine
112734-22-2

4-bromo-2-fluorobenzylamine

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Stage #1: (2R)-2-ethoxycarbonyl-2-(pyrrol-1-yl)succinimide diisopropylamine salt With sulfuric acid; water In ethyl acetate
Stage #2: With trifluoroacetyl chloride In ethyl acetate for 6h; Heating / reflux;
Stage #3: 4-bromo-2-fluorobenzylamine With water; sodium hydrogencarbonate; diisopropylamine more than 3 stages;
58%
(4-bromo-2-fluorophenyl)methanamine hydrochloride

(4-bromo-2-fluorophenyl)methanamine hydrochloride

R-(-)-3-ethoxycarbonyl-3-(2-(trichloroacetyl)pyrrol-1-yl)pyrrolidin-2,5-dione
159213-26-0

R-(-)-3-ethoxycarbonyl-3-(2-(trichloroacetyl)pyrrol-1-yl)pyrrolidin-2,5-dione

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 16h; Ambient temperature;45%
(R)-ethyl-3-amino-2,5-dioxopyrrolidine-3-carboxylate
159213-18-0

(R)-ethyl-3-amino-2,5-dioxopyrrolidine-3-carboxylate

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 72.4 percent / AcOH / 1.5 h / 70 °C
2: 91.9 percent / CHCl3 / 16 h / Heating
3: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1.1: water / Heating
1.2: 22; 13 / 12 h / 40 °C
2.1: 10 h / 80 °C
3.1: N,N-dimethyl-formamide / 5 h / 20 °C
View Scheme
ethyl 2,5-dioxo-3-(1H-pyrrol-1-yl)pyrrolidine-3-carboxylate
159213-19-1

ethyl 2,5-dioxo-3-(1H-pyrrol-1-yl)pyrrolidine-3-carboxylate

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91.9 percent / CHCl3 / 16 h / Heating
2: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: ethyl acetate / Reflux
2: triethylamine / N,N-dimethyl-formamide / 8 h / 20 °C
View Scheme
ethyl 3-benzyloxycarbonylamino-2,5-dioxopyrrolidine-3-carboxylate
147194-10-3

ethyl 3-benzyloxycarbonylamino-2,5-dioxopyrrolidine-3-carboxylate

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Multi-step reaction with 5 steps
2: 95.9 percent / H2 / 5percent Pd/C / ethanol / 40 - 50 °C / 760 Torr
3: 72.4 percent / AcOH / 1.5 h / 70 °C
4: 91.9 percent / CHCl3 / 16 h / Heating
5: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature
View Scheme
(R)-2-benzyloxycarbonylamino-2-ethoxycarbonylsuccinimide
159213-17-9

(R)-2-benzyloxycarbonylamino-2-ethoxycarbonylsuccinimide

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 95.9 percent / H2 / 5percent Pd/C / ethanol / 40 - 50 °C / 760 Torr
2: 72.4 percent / AcOH / 1.5 h / 70 °C
3: 91.9 percent / CHCl3 / 16 h / Heating
4: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature
View Scheme
ethyl (R)-3-hydrazinyl-2,5-dioxopyrrolidine-3-carboxylate hydrochloride
952656-32-5

ethyl (R)-3-hydrazinyl-2,5-dioxopyrrolidine-3-carboxylate hydrochloride

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: hydrogen / nickel / ethanol / 42 h / 20 °C
2.1: water / Heating
2.2: 22; 13 / 12 h / 40 °C
3.1: 10 h / 80 °C
4.1: N,N-dimethyl-formamide / 5 h / 20 °C
View Scheme
R-(-)-3-ethoxycarbonyl-3-(N,N'-di(tert-butoxycarbonyl)hydrazino)pyrrolidin-2,5-dione hydrochloride

R-(-)-3-ethoxycarbonyl-3-(N,N'-di(tert-butoxycarbonyl)hydrazino)pyrrolidin-2,5-dione hydrochloride

ranirestat
147254-64-6

ranirestat

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: hydrogenchloride / toluene / 2.5 h / 0 °C
2.1: hydrogen / nickel / ethanol / 42 h / 20 °C
3.1: water / Heating
3.2: 22; 13 / 12 h / 40 °C
4.1: 10 h / 80 °C
5.1: N,N-dimethyl-formamide / 5 h / 20 °C
View Scheme
uridine diphosphoglucuronic acid
2616-64-0, 7305-43-3, 50722-58-2

uridine diphosphoglucuronic acid

ranirestat
147254-64-6

ranirestat

AS-3201 N-glucuronide

AS-3201 N-glucuronide

Conditions
ConditionsYield
With human liver microsomes; magnesium chloride In various solvents at 37℃; for 20h; pH=7.1; Enzyme kinetics; Further Variations:; Reagents;
ranirestat
147254-64-6

ranirestat

AS-3201 N-glucoside

AS-3201 N-glucoside

Conditions
ConditionsYield
With human liver microsomes; magnesium chloride In various solvents at 37℃; for 2h; pH=7.1; Enzyme kinetics; Further Variations:; Reagents;

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