(3R)-2'-(4-Bromo-2-fluorobenzyl)spiro[pyrrolidine-3,4'-1'H-pyrrolo[1,2-a]pyrazine]-1',2,3',5(2'H)-tetraone CAS:147254-64-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating rese
Cas:147254-64-6
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:147254-64-6
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:147254-64-6
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
Cas:147254-64-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
Cas:147254-64-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:147254-64-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China
We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:clear liquid Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:147254-64-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:147254-64-6
Min.Order:0
Negotiable
Type:Trading Company
inquiry1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
good quality and best price Application:R&D for pharmaceutical Port:Shanghai
instock with good quality and wholesale price Storage:Keep in a cool & dry place Package:Packing material and QTY as your request Application:Pharma;Industry;other application Transportation:Express or as your request Port:Any port of China
Cas:147254-64-6
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryKnown for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar
Our company provides the best service for our customers. Under the premise of ensuring quality and delivery date, give customers the best price. The company is more willing to meet our customers. If you want to visit our factories and warehouses, we
Cas:147254-64-6
Min.Order:0
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Type:Trading Company
inquiry(S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate
ranirestat
Conditions | Yield |
---|---|
With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; Inert atmosphere; | 95% |
4-bromo-2-fluorobenzylamine
R-(-)-3-ethoxycarbonyl-3-(2-(trichloroacetyl)pyrrol-1-yl)pyrrolidin-2,5-dione
ranirestat
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 20℃; for 5h; | 71% |
With triethylamine In N,N-dimethyl-formamide at 20℃; | 65% |
With triethylamine In N,N-dimethyl-formamide at 20℃; for 8h; | 65% |
(2R)-2-ethoxycarbonyl-2-(pyrrol-1-yl)succinimide diisopropylamine salt
4-bromo-2-fluorobenzylamine
ranirestat
Conditions | Yield |
---|---|
Stage #1: (2R)-2-ethoxycarbonyl-2-(pyrrol-1-yl)succinimide diisopropylamine salt With sulfuric acid; water In ethyl acetate Stage #2: With trifluoroacetyl chloride In ethyl acetate for 6h; Heating / reflux; Stage #3: 4-bromo-2-fluorobenzylamine With water; sodium hydrogencarbonate; diisopropylamine more than 3 stages; | 58% |
R-(-)-3-ethoxycarbonyl-3-(2-(trichloroacetyl)pyrrol-1-yl)pyrrolidin-2,5-dione
ranirestat
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide for 16h; Ambient temperature; | 45% |
(R)-ethyl-3-amino-2,5-dioxopyrrolidine-3-carboxylate
ranirestat
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 72.4 percent / AcOH / 1.5 h / 70 °C 2: 91.9 percent / CHCl3 / 16 h / Heating 3: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature View Scheme | |
Multi-step reaction with 3 steps 1.1: water / Heating 1.2: 22; 13 / 12 h / 40 °C 2.1: 10 h / 80 °C 3.1: N,N-dimethyl-formamide / 5 h / 20 °C View Scheme |
ethyl 2,5-dioxo-3-(1H-pyrrol-1-yl)pyrrolidine-3-carboxylate
ranirestat
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 91.9 percent / CHCl3 / 16 h / Heating 2: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature View Scheme | |
Multi-step reaction with 2 steps 1: ethyl acetate / Reflux 2: triethylamine / N,N-dimethyl-formamide / 8 h / 20 °C View Scheme |
ethyl 3-benzyloxycarbonylamino-2,5-dioxopyrrolidine-3-carboxylate
ranirestat
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 2: 95.9 percent / H2 / 5percent Pd/C / ethanol / 40 - 50 °C / 760 Torr 3: 72.4 percent / AcOH / 1.5 h / 70 °C 4: 91.9 percent / CHCl3 / 16 h / Heating 5: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature View Scheme |
(R)-2-benzyloxycarbonylamino-2-ethoxycarbonylsuccinimide
ranirestat
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 95.9 percent / H2 / 5percent Pd/C / ethanol / 40 - 50 °C / 760 Torr 2: 72.4 percent / AcOH / 1.5 h / 70 °C 3: 91.9 percent / CHCl3 / 16 h / Heating 4: 45 percent / Et3N / dimethylformamide / 16 h / Ambient temperature View Scheme |
ethyl (R)-3-hydrazinyl-2,5-dioxopyrrolidine-3-carboxylate hydrochloride
ranirestat
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: hydrogen / nickel / ethanol / 42 h / 20 °C 2.1: water / Heating 2.2: 22; 13 / 12 h / 40 °C 3.1: 10 h / 80 °C 4.1: N,N-dimethyl-formamide / 5 h / 20 °C View Scheme |
ranirestat
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: hydrogenchloride / toluene / 2.5 h / 0 °C 2.1: hydrogen / nickel / ethanol / 42 h / 20 °C 3.1: water / Heating 3.2: 22; 13 / 12 h / 40 °C 4.1: 10 h / 80 °C 5.1: N,N-dimethyl-formamide / 5 h / 20 °C View Scheme |
uridine diphosphoglucuronic acid
ranirestat
Conditions | Yield |
---|---|
With human liver microsomes; magnesium chloride In various solvents at 37℃; for 20h; pH=7.1; Enzyme kinetics; Further Variations:; Reagents; |
diphosphoric acid 1''-β-D-[1'']glucopyranosyl ester 2-(uridin-5'-yl)ester
ranirestat
Conditions | Yield |
---|---|
With human liver microsomes; magnesium chloride In various solvents at 37℃; for 2h; pH=7.1; Enzyme kinetics; Further Variations:; Reagents; |
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