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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

(S)-2-AMINO-3,3-DIPHENYLPROPAN-1-OL

Cas:162118-01-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

(S)-DIPHENYLALANINOL CAS:162118-01-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in

(S)-DIPHENYLALANINOL CAS:162118-01-6

Cas:162118-01-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

162118-01-6

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzenepropanol, b-aMino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

(2S)-2-AMINO-3,3-DIPHENYLPROPAN-1-OLCASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(2S)-2-AMINO-3,3-DIPHENYLPROPAN-1-OLCAS

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S)-DIPHENYLALANINOL

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

(S)-DIPHENYLALANINOL

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SAGECHEM LIMITED

162118-01-6 Application:intermediate

Benzenepropanol, b-amino-g-phenyl-, (S)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

(S)-DIPHENYLALANINOL

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Bide Pharmatech Ltd

Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical

(S)-2-Amino-3,3-diphenylpropan-1-ol

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Other

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

(S)-2-Amino-3,3-diphenylpropan-1-ol

Cas:162118-01-6

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

(S)-DIPHENYLALANINOL

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Chemlin Chemical Co., Ltd.

please contact us to confirm the required quantity and quote, we will provide you with COA,NMR,HPLC and other relevant information Storage:Store in a cool place. Keep container tightly closed in a dry and well-ventilated place Package:as your needs A

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Nanjing Raymon Biotech Co., Ltd.

Benzenepropanol, b-amino-g-phenyl-, (bS)- Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shanghai/S

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changzhou Run-chem Biological Co.,ltd

(S)-2-Amino-3,3-diphenylpropan-1-ol, 97%, 162118-01-6 Storage:dry and ventilated place Package:suitable for shipping Application:(S)-2-Amino-3,3-diphenylpropan-1-ol, 97%, 162118-01-6 Transportation:air or sea shipping Port:shanghai

(S)-2-Amino-3,3-diphenylpropan-1-ol, 97%, 162118-01-6

Cas:162118-01-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Ruishun Trade Co.,Ltd

Supply top quality products with a reasonable price Application:api

162118-01-6

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chengdu NoVi Biotechnology Co., Ltd.

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Co.Ltd

Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

Benzenepropanol, b-amino-g-phenyl-, (bS)-

Cas:162118-01-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DSM Pharma Chemicals

more information,please contact us

(S)-DIPHENYLALANINOL

Cas:162118-01-6

Min.Order:0

Negotiable

Type:

inquiry

Synthetic route

tert-butyl N-[(1S)-1-(hydroxymethyl)-2,2-diphenylethyl]carbamate
155836-47-8

tert-butyl N-[(1S)-1-(hydroxymethyl)-2,2-diphenylethyl]carbamate

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran at 20℃; for 48h; Hydrolysis;100%
With trifluoroacetic acid for 1h; Cooling with ice;
C25H22N4O3

C25H22N4O3

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 60℃;
3-(1-imidazolyl)benzonitrile
25699-85-8

3-(1-imidazolyl)benzonitrile

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C25H21N3O

C25H21N3O

Conditions
ConditionsYield
With zinc(II) trifluoroacetate In chlorobenzene at 130℃; for 48h; Inert atmosphere; Schlenk technique;93%
diethyl malonoimidate dihydrochloride
10344-69-1

diethyl malonoimidate dihydrochloride

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

bis((S)-4-benzhydryl-4,5-dihydrooxazol-2-yl)methane

bis((S)-4-benzhydryl-4,5-dihydrooxazol-2-yl)methane

Conditions
ConditionsYield
In dichloromethane at 40℃; for 8h;75%
quinoline-2-carbonitrile
1436-43-7

quinoline-2-carbonitrile

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-2-(quinolin-2-yl)-4,5-dihydrooxazole

(S)-4-benzhydryl-2-(quinolin-2-yl)-4,5-dihydrooxazole

Conditions
ConditionsYield
Stage #1: quinoline-2-carbonitrile With sodium methylate In methanol at 20℃;
Stage #2: (S)-2-amino-3,3-diphenyl-1-propanol With toluene-4-sulfonic acid In toluene at 80℃;
64%
ethyl 5-(benzyloxy)-6-((2-methoxyethyl)carbamoyl)-4-oxo-4H-pyran-3-carboxylate
1246616-94-3

ethyl 5-(benzyloxy)-6-((2-methoxyethyl)carbamoyl)-4-oxo-4H-pyran-3-carboxylate

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

ethyl (S)-5-(benzyloxy)-1-(3-hydroxy-1,1-diphenylpropan-2-yl)-6-((2-methoxyethyl)carbamoyl)-4-oxo-1,4-dihydropyridine-3-carboxylate
1370248-11-5

ethyl (S)-5-(benzyloxy)-1-(3-hydroxy-1,1-diphenylpropan-2-yl)-6-((2-methoxyethyl)carbamoyl)-4-oxo-1,4-dihydropyridine-3-carboxylate

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene at 120℃; for 0.5h;52%
With triethylamine In toluene at 90℃; for 1h;9.12 g
pyridine-2,6-dinitrile
2893-33-6

pyridine-2,6-dinitrile

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

2,6-bis((S)-4-benzhydryl-4,5-dihydrooxazol-2-yl)pyridine

2,6-bis((S)-4-benzhydryl-4,5-dihydrooxazol-2-yl)pyridine

Conditions
ConditionsYield
With zinc trifluoromethanesulfonate In toluene for 48h; Reflux;35%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

tert-butyl N-[(1S)-1-(hydroxymethyl)-2,2-diphenylethyl]carbamate
155836-47-8

tert-butyl N-[(1S)-1-(hydroxymethyl)-2,2-diphenylethyl]carbamate

Conditions
ConditionsYield
In dichloromethane
5-chlorothien-2-ylsulfonyl chloride
2766-74-7

5-chlorothien-2-ylsulfonyl chloride

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C19H18ClNO3S2
1132652-97-1

C19H18ClNO3S2

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran
diphenylamine-2,2'-dicarbonyl chloride
32621-46-8

diphenylamine-2,2'-dicarbonyl chloride

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C44H41N3O4

C44H41N3O4

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

ethyl (S)-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxylate
1370248-12-6

ethyl (S)-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: triethylamine / toluene / 1 h / 90 °C
2: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid
1370248-13-7

(S)-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: triethylamine / toluene / 1 h / 90 °C
2: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-hydroxy-2-(2-methoxyethyl)-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid
1370237-33-4

(S)-4-benzhydryl-9-hydroxy-2-(2-methoxyethyl)-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: triethylamine / toluene / 1 h / 90 °C
2: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4: palladium 10% on activated carbon; hydrogen / methanol / 1 h
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C32H32N2O5
1370248-22-8

C32H32N2O5

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.33 h / 0 °C
4.2: 2.5 h / 0 - 20 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C25H26N2O5
1370237-80-1

C25H26N2O5

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.33 h / 0 °C
4.2: 2.5 h / 0 - 20 °C
5.1: trifluoroacetic acid / 1 h / 20 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-(benzyloxy)-N-methoxy-2-(2-methoxyethyl)-N-methyl-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide
1370248-38-6

(S)-4-benzhydryl-9-(benzyloxy)-N-methoxy-2-(2-methoxyethyl)-N-methyl-1,8-dioxo-1,3,4,8-tetrahydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Cooling with ice
4.2: 1 h / 20 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-7-acetyl-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione
1370248-39-7

(S)-7-acetyl-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Cooling with ice
4.2: 1 h / 20 °C
5.1: tetrahydrofuran / 0.5 h / -78 - -50 °C / Inert atmosphere
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C33H32N2O6
1370248-40-0

C33H32N2O6

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Cooling with ice
4.2: 1 h / 20 °C
5.1: tetrahydrofuran / 0.5 h / -78 - -50 °C / Inert atmosphere
6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-(benzyloxy)-7-hydroxy-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione
1370248-41-1

(S)-4-benzhydryl-9-(benzyloxy)-7-hydroxy-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Cooling with ice
4.2: 1 h / 20 °C
5.1: tetrahydrofuran / 0.5 h / -78 - -50 °C / Inert atmosphere
6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
7.1: ethanol / 4 h / Reflux
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-(benzyloxy)-7-methoxy-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione
1370248-42-2

(S)-4-benzhydryl-9-(benzyloxy)-7-methoxy-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Cooling with ice
4.2: 1 h / 20 °C
5.1: tetrahydrofuran / 0.5 h / -78 - -50 °C / Inert atmosphere
6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
7.1: ethanol / 4 h / Reflux
8.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / Cooling with ice
8.2: 1.5 h / 20 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-hydroxy-7-methoxy-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione
1370237-92-5

(S)-4-benzhydryl-9-hydroxy-7-methoxy-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1.1: triethylamine / toluene / 1 h / 90 °C
2.1: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3.1: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4.1: chloroformic acid ethyl ester; triethylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C / Cooling with ice
4.2: 1 h / 20 °C
5.1: tetrahydrofuran / 0.5 h / -78 - -50 °C / Inert atmosphere
6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere
7.1: ethanol / 4 h / Reflux
8.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / Cooling with ice
8.2: 1.5 h / 20 °C
9.1: trifluoroacetic acid / 0.5 h / 20 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione
1370248-43-3

(S)-4-benzhydryl-9-(benzyloxy)-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: triethylamine / toluene / 1 h / 90 °C
2: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4: diphenylether / 1 h / 245 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-9-(benzyloxy)-7-bromo-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione
1370248-44-4

(S)-4-benzhydryl-9-(benzyloxy)-7-bromo-2-(2-methoxyethyl)-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,8-dione

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: triethylamine / toluene / 1 h / 90 °C
2: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4: diphenylether / 1 h / 245 °C
5: N-Bromosuccinimide / dichloromethane / 1 h / Reflux
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

C24H23BrN2O4
1370237-93-6

C24H23BrN2O4

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: triethylamine / toluene / 1 h / 90 °C
2: triphenylphosphine; diethylazodicarboxylate / toluene; tetrahydrofuran / 20 h / 20 °C / Cooling with ice
3: sodium hydroxide; water / ethanol / 1.17 h / 20 °C
4: diphenylether / 1 h / 245 °C
5: N-Bromosuccinimide / dichloromethane / 1 h / Reflux
6: trifluoroacetic acid / 0.83 h / 20 °C
View Scheme
2,2-dimethylpent-4-enoic acid
16386-93-9

2,2-dimethylpent-4-enoic acid

(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(S)-4-benzhydryl-2-(2-methylpent-4-en-2-yl)-4,5-dihydrooxazole

(S)-4-benzhydryl-2-(2-methylpent-4-en-2-yl)-4,5-dihydrooxazole

Conditions
ConditionsYield
Stage #1: 2,2-dimethylpent-4-enoic acid; (S)-2-amino-3,3-diphenyl-1-propanol With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane; N,N-dimethyl-formamide at 20℃;
Stage #2: With dmap; methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 20℃;
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(4S,4'S)-2,2'-(pentane-3,3-diyl)bis(4-benzhydryl-4,5-dihydrooxazole)

(4S,4'S)-2,2'-(pentane-3,3-diyl)bis(4-benzhydryl-4,5-dihydrooxazole)

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: dichloromethane / 8 h / 40 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 20 °C
2.2: 8 h / 60 °C
View Scheme
(S)-2-amino-3,3-diphenyl-1-propanol
162118-01-6

(S)-2-amino-3,3-diphenyl-1-propanol

(4S,4'S)-2,2'-(cyclopentane-1,1-diyl)bis(4-benzhydryl-4,5-dihydrooxazole)

(4S,4'S)-2,2'-(cyclopentane-1,1-diyl)bis(4-benzhydryl-4,5-dihydrooxazole)

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: dichloromethane / 8 h / 40 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 - 20 °C
2.2: 8 h / 60 °C
View Scheme

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