As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:172900-83-3
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:172900-83-3
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:172900-83-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:172900-83-3
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryHunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
Cas:172900-83-3
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou
factory?direct?sale Application:healing drugs
Cas:172900-83-3
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquirygood quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran
Carbamic acid,[3-[[4-(1,1-dimethylethyl)phenyl]methyl]-1-formyl-4-methylpentyl]-,1,1-dimethylethyl ester, [S-(R*,R*)]-Carbamic acid,Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:phar
Cas:172900-83-3
Min.Order:0
Negotiable
Type:Other
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China
Cas:172900-83-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Our mission is to provide high-quality and innovative products to our customers. By offering a broad range of products, custom synthesis and personalized services, Bide can help scientists speeding up their research in the chemical and pharmaceutical
Cas:172900-83-3
Min.Order:0
Negotiable
Type:Other
inquiry1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:172900-83-3
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquirywe have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survi
Cas:172900-83-3
Min.Order:10 Gram
FOB Price: $1.0
Type:Trading Company
inquiryAopharm is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in modes of
We are able to provide you best product with best price. Application:medical intermediate Port:shanghai,ningbo
Cas:172900-83-3
Min.Order:100 Kilogram
Negotiable
Type:Trading Company
inquirytert-Butyl ((2S,4S)-4-(4-methoxy-3-(3-methoxypropoxy)benzyl)-5-methyl-1-oxohexan-2-yl)carbamate Application:80077214
Cas:172900-83-3
Min.Order:1 Gram
FOB Price: $500.0
Type:Trading Company
inquiryCas:172900-83-3
Min.Order:0
Negotiable
Type:Other
inquiryGood Price, prompt shipment Application:Medical intermediate; Used in organic synthesis
Package:5KG; 1KG; 500G; 100G
Cas:172900-83-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryCas:172900-83-3
Min.Order:0
Negotiable
Type:Trading Company
inquiryR & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
(2S,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexan-1-ol
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
With sulfur trioxide pyridine complex; triethylamine In dimethyl sulfoxide at 0 - 20℃; for 1h; | 100% |
With sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine at 0 - 20℃; for 1h; | 100% |
With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane Swern oxidation; | 89% |
methyl (2S,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexanoate
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
With diisobutylaluminium hydride In toluene at -75℃; for 0.833333h; | |
Multi-step reaction with 2 steps 1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 2: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(2R,5S)-3,6-diethoxy-2-isopropyl-5-((S)-2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutyl)-2,5-dihydropyrazine
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: HCl / acetonitrile 2: Et3N 3: NaBH4 / ethanol 4: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
isovanillin
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 12 steps 1: 98 percent / K2CO3 / acetonitrile 2: NaBH4 / ethanol 3: PBr3 / CH2Cl2 4: 76 percent / LiHMDS / tetrahydrofuran 5: 81 percent / LiOH; H2O2 6: 95 percent / LAH / tetrahydrofuran 7: 97 percent / PPh3; NBS / CH2Cl2 8: 68 percent / n-BuLi 9: HCl / acetonitrile 10: Et3N 11: NaBH4 / ethanol 12: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 11 steps 1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran; toluene / 24 h / 20 °C 2.1: sodium tetrahydroborate; ethanol / 20 °C 3.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / 20 °C 4.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 4.2: 20 °C / Cooling with acetone-dry ice 5.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 6.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 7.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 7.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 8.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 8.2: 0 °C 9.1: dichloromethane / 14 h / 20 °C 10.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 11.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(R)-4-benzyl-3-(3-methylbutyryl)oxazolidin-2-one
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: 76 percent / LiHMDS / tetrahydrofuran 2: 81 percent / LiOH; H2O2 3: 95 percent / LAH / tetrahydrofuran 4: 97 percent / PPh3; NBS / CH2Cl2 5: 68 percent / n-BuLi 6: HCl / acetonitrile 7: Et3N 8: NaBH4 / ethanol 9: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 8 steps 1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 1.2: 20 °C / Cooling with acetone-dry ice 2.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 3.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 4.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 5.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 5.2: 0 °C 6.1: dichloromethane / 14 h / 20 °C 7.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 8.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
4-methoxy-3-(3-methoxypropoxy)benzaldehyde
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 11 steps 1: NaBH4 / ethanol 2: PBr3 / CH2Cl2 3: 76 percent / LiHMDS / tetrahydrofuran 4: 81 percent / LiOH; H2O2 5: 95 percent / LAH / tetrahydrofuran 6: 97 percent / PPh3; NBS / CH2Cl2 7: 68 percent / n-BuLi 8: HCl / acetonitrile 9: Et3N 10: NaBH4 / ethanol 11: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 10 steps 1.1: sodium tetrahydroborate; ethanol / 20 °C 2.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / 20 °C 3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 3.2: 20 °C / Cooling with acetone-dry ice 4.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 5.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 6.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 6.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 7.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 7.2: 0 °C 8.1: dichloromethane / 14 h / 20 °C 9.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 10.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(R)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutanol
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 97 percent / PPh3; NBS / CH2Cl2 2: 68 percent / n-BuLi 3: HCl / acetonitrile 4: Et3N 5: NaBH4 / ethanol 6: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 6 steps 1.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 2.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 2.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 3.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 3.2: 0 °C 4.1: dichloromethane / 14 h / 20 °C 5.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 6.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(R)-3-[4-methoxy-3-(3-methoxypropoxy)phenyl]-2-(1-methylethyl)propanoic acid
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 95 percent / LAH / tetrahydrofuran 2: 97 percent / PPh3; NBS / CH2Cl2 3: 68 percent / n-BuLi 4: HCl / acetonitrile 5: Et3N 6: NaBH4 / ethanol 7: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
4-(bromomethyl)-1-methoxy-2-(3-methoxypropoxy)-benzene
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1: 76 percent / LiHMDS / tetrahydrofuran 2: 81 percent / LiOH; H2O2 3: 95 percent / LAH / tetrahydrofuran 4: 97 percent / PPh3; NBS / CH2Cl2 5: 68 percent / n-BuLi 6: HCl / acetonitrile 7: Et3N 8: NaBH4 / ethanol 9: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 8 steps 1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 1.2: 20 °C / Cooling with acetone-dry ice 2.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 3.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 4.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 5.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 5.2: 0 °C 6.1: dichloromethane / 14 h / 20 °C 7.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 8.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
[4-methoxy-3-(3-methoxypropoxy)-phenyl]methanol
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 10 steps 1: PBr3 / CH2Cl2 2: 76 percent / LiHMDS / tetrahydrofuran 3: 81 percent / LiOH; H2O2 4: 95 percent / LAH / tetrahydrofuran 5: 97 percent / PPh3; NBS / CH2Cl2 6: 68 percent / n-BuLi 7: HCl / acetonitrile 8: Et3N 9: NaBH4 / ethanol 10: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 9 steps 1.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / 20 °C 2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 2.2: 20 °C / Cooling with acetone-dry ice 3.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 4.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 5.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 5.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 6.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 6.2: 0 °C 7.1: dichloromethane / 14 h / 20 °C 8.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 9.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(R)-4-(2-(bromomethyl)-3-methylbutyl)-1-methoxy-2-(3-methoxypropoxy)benzene
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 68 percent / n-BuLi 2: HCl / acetonitrile 3: Et3N 4: NaBH4 / ethanol 5: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
(2S,4S)-2-Amino-4-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-5-methyl-hexanoic acid ethyl ester
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Et3N 2: NaBH4 / ethanol 3: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
ethyl (2S,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexanoate
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NaBH4 / ethanol 2: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
(4R)-3-{(2R)-2-{[4-methoxy-3-(methoxypropoxy)phenyl]methyl-3-methyl}-1-oxobutyl}-4-(phenylmethyl)oxazolidin-2-one
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 81 percent / LiOH; H2O2 2: 95 percent / LAH / tetrahydrofuran 3: 97 percent / PPh3; NBS / CH2Cl2 4: 68 percent / n-BuLi 5: HCl / acetonitrile 6: Et3N 7: NaBH4 / ethanol 8: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
Multi-step reaction with 7 steps 1.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 2.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 3.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 3.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 4.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 4.2: 0 °C 5.1: dichloromethane / 14 h / 20 °C 6.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 7.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(R)-4-(2-(iodomethyl)-3-methylbutyl)-1-methoxy-2-(3-methoxypropoxy)benzene
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 1.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 2.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 2.2: 0 °C 3.1: dichloromethane / 14 h / 20 °C 4.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 5.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
isopentanoyl chloride
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / Cooling with acetone-dry ice 1.2: 2.33 h / 0 °C / Cooling with acetone-dry ice 2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 2.2: 20 °C / Cooling with acetone-dry ice 3.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 4.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 5.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 5.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 6.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 6.2: 0 °C 7.1: dichloromethane / 14 h / 20 °C 8.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 9.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
methyl (2S,4S)-2-amino-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexanoate
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: dichloromethane / 14 h / 20 °C 2: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 3: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(2S,5R)-2,5-dihydro-3,6-dimethoxy-2-{(2S)-2-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-3-methylbutyl}-5-(1-methylethyl)pyrazine
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 1.2: 0 °C 2.1: dichloromethane / 14 h / 20 °C 3.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 4.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
(2S)-(benzyloxymethyl)-3-methyl-butyl bromide
Conditions | Yield |
---|---|
Stage #1: (2S)-(benzyloxymethyl)-3-methyl-butyl bromide With magnesium; ethylene dibromide In tetrahydrofuran at 55℃; for 0.333333h; Stage #2: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran at 20℃; for 3h; Further stages.; | 53% |
With magnesium | |
Stage #1: (2S)-(benzyloxymethyl)-3-methyl-butyl bromide With magnesium; ethylene dibromide In tetrahydrofuran at 55℃; for 0.833333h; Stage #2: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran at 5 - 20℃; for 3h; |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
tert-butyl (1S,3S)-3-(3-(3-methoxypropoxy)-4-methoxybenzyl)-4-methyl-1-((R)-oxiran-2-yl)pentylcarbamate
Conditions | Yield |
---|---|
Stage #1: trimethylsulfoxonium iodide With sodium hydride In dimethyl sulfoxide at 20℃; for 1h; Stage #2: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran; dimethyl sulfoxide at 20℃; for 1h; | 46% |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
trimethylsulfoxonium iodide
tert-butyl (1S,3S)-3-(3-(3-methoxypropoxy)-4-methoxybenzyl)-4-methyl-1-((R)-oxiran-2-yl)pentylcarbamate
Conditions | Yield |
---|---|
Stage #1: trimethylsulfoxonium iodide With sodium hydride In dimethyl sulfoxide at 20℃; for 1h; Stage #2: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran; dimethyl sulfoxide at 20℃; for 1h; Product distribution / selectivity; | 46% |
Stage #1: trimethylsulfoxonium iodide With potassium tert-butylate at 20℃; Stage #2: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran; dimethyl sulfoxide at 0℃; for 2h; |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
methacrylic acid N-(butyl)amide
Conditions | Yield |
---|---|
Stage #1: methacrylic acid N-(butyl)amide With n-butyllithium In tetrahydrofuran; hexane at -78 - 0℃; for 0.5h; Stage #2: With triisopropoxytitanium(IV) chloride In tetrahydrofuran; hexane at -78℃; for 0.916667h; Stage #3: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran; hexane at -78℃; for 1.5h; Further stages.; | A 76 g B 188 g |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Mg 2: H2 / Pd(OH)2/C 3: TPAP; NMMO View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
tert-butyl {(1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}carbamate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Mg 2: 23 percent / H2 / Pd(OH)2/C 3: 38 percent / TPAP; NMMO View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
((1S,2R,4S)-2-Hydroxy-4-hydroxymethyl-1-{(S)-2-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-3-methyl-butyl}-5-methyl-hexyl)-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: Mg 2: H2 / Pd(OH)2/C View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
((1S,2S,4S)-2-hydroxy-4-hydroxymethyl-1-((S)-2-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-3-methyl-butyl)-5-methyl-hexyl)-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: Mg 2: 23 percent / H2 / Pd(OH)2/C View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: Mg 2: H2 / Pd(OH)2/C 3: TPAP; NMMO 4: 2-hydroxypyridine; Et3N 5: TMSCl; phenol / CH2Cl2 View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: Mg 2: H2 / Pd(OH)2/C 3: TPAP; NMMO 4: 2-hydroxypyridine; Et3N View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
tert-butyl (3S,5S,6S,8S)-8-(3-amino-2,2-dimethyl-3-oxopropylcarbamoyl)-6-hydroxy-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-2,9-dimethyldecan-5-ylcarbamate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: Mg 2: 23 percent / H2 / Pd(OH)2/C 3: 38 percent / TPAP; NMMO 4: 65 percent / 2-hydroxypyridine; Et3N View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
(2S,4S,5S,7S)-5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: Mg 2: 23 percent / H2 / Pd(OH)2/C 3: 38 percent / TPAP; NMMO 4: 65 percent / 2-hydroxypyridine; Et3N 5: TMSCl; phenol / CH2Cl2 View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
propynoic acid ethyl ester
(4S,5S,7S)-5-tert-Butoxycarbonylamino-4-hydroxy-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methylnon-2-ynoic acid ethyl ester
Conditions | Yield |
---|---|
Stage #1: propynoic acid ethyl ester With lithium diisopropyl amide In tetrahydrofuran for 0.5h; Stage #2: (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester In tetrahydrofuran at -78℃; for 1h; |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
tert-butyl {1(S)-(2-amino-1(S)-hydroxyethyl)-3(S)-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}carbamate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: sodium hydride / dimethyl sulfoxide / 1 h / 20 °C 1.2: 1 h / 20 °C 2.1: ammonia; water / methanol / 20 °C View Scheme |
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: sodium hydride / dimethyl sulfoxide / 1 h / 20 °C 1.2: 1 h / 20 °C 2.1: acetonitrile / 0.33 h / 90 °C / Microwave View Scheme |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View