CAS No.187960-74-3,3,5-BIS[2-(BOC-AMINO)ETHOXY]-BENZOIC ACID Suppliers

Hangzhou J&H Chemical Co., Ltd.

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Benzoic acid,3,5-bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-

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Hunan chemfish Pharmaceutical co.,Ltd

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3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3,5-Bis[2-(Boc-aMino)ethoxy]-benzoic acid

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Hangzhou Fandachem Co.,Ltd

3;5-BIS[2-(BOC-AMINO)ETHOXY]BENZOIC ACIDAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

3;5-BIS[2-(BOC-AMINO)ETHOXY]BENZOIC ACID

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Hunan Russell Chemicals Technology Co.,Ltd

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3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid 187960-74-3

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Shenzhen Foris Technology Co. LTD

3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid 187960-74-3

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3,5-BIS[2-(BOC-AMINO)ETHOXY]-BENZOIC ACID

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Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Benzoic acid,3,5-bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-

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Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid, CAS:187960-74-3 with the most competitive p

3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid

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Pure Chemistry Scientific Inc.

3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid Application:2055102

3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid

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Wuhan Chemwish Technology Co., Ltd

High quality Products with prompt delivery Package:based on customer requirement Application:organic intermediates Transportation:By are or by sea Port:any port of China

3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid

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NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

3,5-Bis[2-(Boc-amino)ethoxy]benzoic acid

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Tebu

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3,5-BIS[2-(BOC-AMINO)ETHOXY]-BENZOIC ACID

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Synthetic route

: 184916-28-7
3,5-bis-(2-tert-butyloxycarbonylamino-ethoxy) methyl benzoate

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

Conditions

Conditions	Yield
With sodium hydroxide	100%
With sodium hydroxide In 1,4-dioxane; methanol; water for 5h;	96%
With water; sodium hydroxide In 1,4-dioxane; methanol for 5h;	96%

: 24424-99-5
di-tert-butyl dicarbonate

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: NEt3 / CH2Cl2 / 27 h / 0 °C 2: 64 percent / K2CO3 / dimethylformamide / 16 h / 40 °C 3: 95 percent / Tesser's base / 4.5 h / 20 °C View Scheme
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 24 h / 0 °C 2: potassium carbonate; N,N-dimethyl-formamide / 16 h / 50 °C 3: sodium hydroxide / water; methanol; 1,4-dioxane / 5 h View Scheme
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 24 h / 0 °C 2: potassium carbonate / N,N-dimethyl-formamide / 16 h / 50 °C 3: sodium hydroxide; water / methanol; 1,4-dioxane / 5 h View Scheme

: 2150-44-9
1-carbomethoxy-3,5-dihydroxybenzene

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 64 percent / K2CO3 / dimethylformamide / 16 h / 40 °C 2: 95 percent / Tesser's base / 4.5 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: K2CO3 / dimethylformamide 2: NaOH View Scheme
Multi-step reaction with 2 steps 1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 50 °C 2: sodium hydroxide; water / methanol; 1,4-dioxane / 5 h View Scheme
Multi-step reaction with 2 steps 1.1: potassium iodide; potassium carbonate / acetone / 16 h / 65 °C / Inert atmosphere 2.1: sodium hydroxide / water; methanol / 2 h / 70 °C / Inert atmosphere 2.2: pH 3 / Inert atmosphere View Scheme

: 99-10-5
3,5-Dihydroxybenzoic acid

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 90 percent / H2SO4 / Heating 2: 64 percent / K2CO3 / dimethylformamide / 16 h / 40 °C 3: 95 percent / Tesser's base / 4.5 h / 20 °C View Scheme
Multi-step reaction with 3 steps 1: sulfuric acid / Reflux 2: potassium carbonate; N,N-dimethyl-formamide / 16 h / 50 °C 3: sodium hydroxide / water; methanol; 1,4-dioxane / 5 h View Scheme
Multi-step reaction with 3 steps 1: sulfuric acid / Reflux 2: potassium carbonate / N,N-dimethyl-formamide / 16 h / 50 °C 3: sodium hydroxide; water / methanol; 1,4-dioxane / 5 h View Scheme

: 39684-80-5
2-(tert-butoxycarbonylamino)ethyl bromide

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 64 percent / K2CO3 / dimethylformamide / 16 h / 40 °C 2: 95 percent / Tesser's base / 4.5 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: K2CO3 / dimethylformamide 2: NaOH View Scheme
Multi-step reaction with 2 steps 1: potassium carbonate; N,N-dimethyl-formamide / 16 h / 50 °C 2: sodium hydroxide / water; methanol; 1,4-dioxane / 5 h View Scheme
Multi-step reaction with 2 steps 1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 50 °C 2: sodium hydroxide; water / methanol; 1,4-dioxane / 5 h View Scheme
Multi-step reaction with 2 steps 1.1: potassium iodide; potassium carbonate / acetone / 16 h / 65 °C / Inert atmosphere 2.1: sodium hydroxide / water; methanol / 2 h / 70 °C / Inert atmosphere 2.2: pH 3 / Inert atmosphere View Scheme

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: 3,5-Bis-(2-amino-ethoxy)-benzoic acid methyl ester; hydrochloride

: 187960-76-5
3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid methyl ester

Conditions

Conditions	Yield
With BOP-peptide	100%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate	100%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1.5h;	95%

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: 3,5-(di-aminoethoxy)-benzoic acid dihydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In diethyl ether; dichloromethane for 2h;	100%
With hydrogenchloride In diethyl ether; dichloromethane; water for 2h;	100%

: 2687-43-6
O-benzylhydoxylamine hydrochloride

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: 1228435-28-6
N-(benzyloxy)-3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzamide

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	86%

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: N-Fmoc-L-Ser(t-But)-OEt

: N-Boc-L-Phe-L-Ser(t-But)-OEt

Conditions

Conditions	Yield
With potassium fluoride; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine In N,N-dimethyl-formamide at 20℃; for 5h; Substitution;	84%

: C18H33NO7P2

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: C39H63N3O14P2

Conditions

Conditions	Yield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 24h; Inert atmosphere;	65%
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; Inert atmosphere;	65%

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: 352426-84-7
3,5-Bis-{2-[3,5-bis-(2-tert-butoxycarbonylamino-ethoxy)-benzoylamino]-ethoxy}-benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 95 percent / BOP; N,N-diisopropylethylamine (DiPEA) / CH2Cl2 / 1.5 h / 20 °C 2: 94 percent / Tesser's base / 20 °C View Scheme
Multi-step reaction with 2 steps 1: 100 percent / BOP 2: NaOH View Scheme
Multi-step reaction with 2 steps 1: 100 percent / BOP-peptide 2: NaOH View Scheme

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: 1185295-67-3
3,5-bis(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride / dichloromethane; diethyl ether / 2 h 2: sodium carbonate / water; acetone / 18 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: hydrogenchloride / dichloromethane; water; diethyl ether / 2 h 2: sodium carbonate / water; acetone / 18 h / 20 °C View Scheme

: C18H33NO7P2

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: C29H47N3O10P2*2C2HF3O2

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C / Inert atmosphere 2: dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere View Scheme

: C10H9N3O

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: C31H39N5O8

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃;	466 mg

: C21H23N5O4

: 187960-74-3
3,5-bis[2-(tert-butoxycarbonylamino)ethoxy]benzoic acid

: C63H83N9O18

Conditions

Conditions	Yield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃;	70 mg

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