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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

N-BOC-2,5-DIAZA-BICYCLO[2.2.1]HEPTANE

Cas:198989-07-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 198989-07-0 with competitive price

Cas:198989-07-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

N-Boc-2,5-diaza-bicyclo[2.2.1]heptane

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

198989-07-0 CAS NO.198989-07-0

Cas:198989-07-0

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Cas:198989-07-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support

N-Boc-2,5-diaza-bicyclo[2.2.1]heptane

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

198989-07-0

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid tert-butyl esterAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylicacid tert-butyl ester

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Send Pharmaceutical Technology Co., Ltd.

stock,low price,high quality,high purity,good sevice Application:R&D

tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:250mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po

2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hunan Russell Chemicals Technology Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 198989-07-0

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shenzhen Foris Technology Co. LTD

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester 198989-07-0

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LEAP CHEM Co., Ltd.

Best Seller, High Quality, Competitive Price, Fast Delivery, Quick ResponseAppearance:powder, or liquid Storage:Stored in room temperature, ventilated place Package:Bottle, barrel, cargo, container, etc. Application:Pharmaceuticals, intermediates, AP

2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid, 1,1-dimethylethyl ester

Cas:198989-07-0

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Changzhou Xuanming Chemical Co., Ltd.

Changzhou Xuanming Chemical Co., Ltd. is dedicated to the technology development, manufacturing, import and export chemicals, which are specialized in pharmaceutical intermediates, pesticide intermediate, industry of fine chemicals and custom synt

2,5-Diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Cas:198989-07-0

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Shanghai AngewChem Co., Ltd.

Shanghai AngewChemCo., Ltd. is an innovative enterprise on fine chemicals and pharmaceuticals. Based on Shanghai R&D center and Hunan chemical manufacturing plant, we offer chemical research, process development, and large-scale production. Com

2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Cas:198989-07-0

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

198989-07-0 CAS NO.198989-07-0

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

N-Boc-2,5-diaza-bicyclo[2.2.1]heptane

Cas:198989-07-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Chemlin Chemical Co., Ltd.

Compound sourcing ServicesAgency of testing serviceFactory audit serviceFounded in Dec. 1999, Nanjing Chemlin Chemical Industrial Co.,Ltd(CHEMLIN) has been covering the business scope from trading of chemicals to custom-synthesis & Manufacturing. Co

198989-07-0

Cas:198989-07-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

2,5-diazabicyclo[2.2.1]heptane dihydrobromide

2,5-diazabicyclo[2.2.1]heptane dihydrobromide

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With triethylamine In methanol at -30 - 25℃;200 mg
1'-(5-(4-acetamidopyridin-2-yl)pyrimidin-2-yl)spiro-[cyclopropane-1,3'-indoline]-6'-carboxylic acid

1'-(5-(4-acetamidopyridin-2-yl)pyrimidin-2-yl)spiro-[cyclopropane-1,3'-indoline]-6'-carboxylic acid

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(1'-(5-(4-acetamidopyridin-2-yl)pyrimidin-2-yl)spiro[cyclopropane-1,3-indolin]-6'-ylcarbonyl)-2,5-diazabicyclo-[2.2.1]heptane-2-carboxylate

tert-butyl 5-(1'-(5-(4-acetamidopyridin-2-yl)pyrimidin-2-yl)spiro[cyclopropane-1,3-indolin]-6'-ylcarbonyl)-2,5-diazabicyclo-[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate In N,N-dimethyl-formamide at 23℃; for 16h;96.5%
Ethyl 4-bromobenzoate
5798-75-4

Ethyl 4-bromobenzoate

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(4-(ethoxycarbonyl)phenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(4-(ethoxycarbonyl)phenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 110℃; for 24h;92%
trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl-2-(trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane-5-carboxylate

tert-butyl-2-(trifluoroacetyl)-2,5-diazabicyclo[2.2.1]heptane-5-carboxylate

Conditions
ConditionsYield
With triethylamine at 0 - 20℃; for 2.5 - 3.5h;87.2%
2-chloropyridine
109-09-1

2-chloropyridine

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With methanesulfonato(2-dicyclohexylphosphino-2’,6’-di-i-propoxy-1,1’-biphenyl)(2’-methylamino-1,1‘-biphenyl-2-yl)palladium(II); sodium t-butanolate In 1,4-dioxane at 100℃; for 12h; Sealed tube; Inert atmosphere;87%
6-chloronicotinonitrile
33252-28-7

6-chloronicotinonitrile

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(5-cyanopyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(5-cyanopyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 1.5h;85%
3-(5-bromo-2-pyrimidinyl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine
651340-91-9

3-(5-bromo-2-pyrimidinyl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-{2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-{2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl}-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium tert-butylate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl In toluene at 60℃;84%
9-ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

9-ethyl-6,6-dimethyl-8-iodo-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

C31H34N4O3

C31H34N4O3

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium(0); sodium hexamethyldisilazane In tetrahydrofuran; 1,4-dioxane at 60℃; Inert atmosphere;59%
7-chlorothiazolo[5,4-d]pyrimidin-5-amine
1211527-74-0

7-chlorothiazolo[5,4-d]pyrimidin-5-amine

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1435954-40-7

tert-butyl 5-(5-aminothiazolo[5,4-d]pyrimidin-7-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 55℃; for 3h;55.5%
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 55℃; for 3h;55.5%
4-Fluoronitrobenzene
350-46-9

4-Fluoronitrobenzene

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

5-(4-nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
877212-94-7

5-(4-nitrophenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
In acetonitrile at 100℃;52%
Stage #1: 4-Fluoronitrobenzene With potassium carbonate In dimethyl sulfoxide at 20℃; for 0.5h;
Stage #2: tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate In dimethyl sulfoxide at 70℃; for 5h;
[(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetic acid
1188374-41-5

[(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetic acid

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

5-{2-[(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetyl}-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester
1232028-17-9

5-{2-[(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetyl}-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
Stage #1: [(5-phenyl-1H-pyrazole-3-carbonyl)-amino]-acetic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.0333333h;
Stage #2: tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate In N,N-dimethyl-formamide at 20℃;
51%
3-bromo-6-chloro-imidazo[1,2-b]pyridazine
13526-66-4

3-bromo-6-chloro-imidazo[1,2-b]pyridazine

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(3-bromoimidazo[1,2-b]pyridazin-6-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
1400874-04-5

tert-butyl 5-(3-bromoimidazo[1,2-b]pyridazin-6-yl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 130℃; for 4h;49%
4-{[(2S,4R)-2-methyl-1-propionyl-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzoic acid

4-{[(2S,4R)-2-methyl-1-propionyl-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzoic acid

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(4-{[(2S,4R)-2-methyl-1-propionyl-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzoyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(4-{[(2S,4R)-2-methyl-1-propionyl-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzoyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;49%
tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

2,3-dimethylbenzoic acid
603-79-2

2,3-dimethylbenzoic acid

5-(2,3-dimethylbenzoyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

5-(2,3-dimethylbenzoyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 17h;42%
2-Fluoro-4-(trifluoromethyl)benzaldehyde
89763-93-9

2-Fluoro-4-(trifluoromethyl)benzaldehyde

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

t-butyl 5-(2-formyl-5-(trifluoromethyl)phenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

t-butyl 5-(2-formyl-5-(trifluoromethyl)phenyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 80℃;34%
para-diiodobenzene
624-38-4

para-diiodobenzene

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

tert-butyl 5-(4-iodophenyl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate
1197294-09-9

tert-butyl 5-(4-iodophenyl)-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylate

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; 1,1'-bi-2-naphthol In N,N-dimethyl-formamide at 80 - 90℃;33%
3-fluoro-2-methylbenzoic acid
699-90-1

3-fluoro-2-methylbenzoic acid

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

5-(3-fluoro-2-methylbenzoyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

5-(3-fluoro-2-methylbenzoyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 17h;31.62%
2-(3-((7-(3-chloropropoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide
722544-46-9

2-(3-((7-(3-chloropropoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

5-(3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

5-(3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl acetamide at 60℃;29%
1-Bromo-2-chloroethane
107-04-0

1-Bromo-2-chloroethane

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate
198989-07-0

tert-butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

5-(2-chloroethyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

5-(2-chloroethyl)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 20℃; for 17h;24.71%

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